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Hydroxyzine (Hydroxyzine Hydrochloride) - Side Effects and Adverse Reactions



Side effects reported with the administration of hydrOXYzine hydrochloride are usually mild and transitory in nature.

Anticholinergic: Dry mouth.

Central Nervous System: Drowsiness is usually transitory and may disappear in a few days of continued therapy or upon reduction of dose. Involuntary motor activity including rare instances of tremor and convulsions have been reported, usually with doses considerably higher than those recommended. Clinically significant respiratory depression has not been reported at recommended doses.


Below is a sample of reports where side effects / adverse reactions may be related to Hydroxyzine. The information is not vetted and should not be considered as verified clinical evidence.

Possible Hydroxyzine side effects / adverse reactions in 73 year old female

Reported by a physician from United States on 2011-10-11

Patient: 73 year old female weighing 77.5 kg (170.5 pounds)

Reactions: Multi-Organ Failure, Intentional Overdose, Liver Function Test Abnormal, Vascular Pseudoaneurysm, Intentional Self-Injury

Adverse event resulted in: death, hospitalization

Suspect drug(s):

    Indication: Product Used FOR Unknown Indication

    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Vitamin B Complex CAP; Vitamin A; Ascorbic Acid; Zinc

Possible Hydroxyzine side effects / adverse reactions in 33 year old male

Reported by a health professional (non-physician/pharmacist) on 2011-10-12

Patient: 33 year old male weighing 84.0 kg (184.8 pounds)

Reactions: Rhabdomyolysis, Autonomic Nervous System Imbalance, Mental Disorder, Blood Pressure Abnormal

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
    Dosage: (40 mg),oral
    Administration route: Oral
    Indication: Blood Cholesterol Increased
    Start date: 2010-11-24
    End date: 2010-12-03

    Dosage: 10 mg (10 mg,1 in 1 d)
    Indication: Pruritus
    End date: 2010-12-01

    Dosage: 20 mg (20 mg,1 in 1 d),oral
    Administration route: Oral
    Indication: Schizophrenia

    Dosage: 400 mg (200 mg,2 in 1 d),oral
    Administration route: Oral
    Indication: Acne
    End date: 2010-12-01

Possible Hydroxyzine side effects / adverse reactions in 77 year old male

Reported by a consumer/non-health professional from United States on 2011-10-13

Patient: 77 year old male

Reactions: Drug Ineffective

Suspect drug(s):

See index of all Hydroxyzine side effect reports >>

Drug label data at the top of this Page last updated: 2012-08-02

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