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Hydroxyurea (Hydroxyurea) - Current Clinical Trials

 
 



Hydroxyurea Related Clinical Trials

Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant Glioma [Completed]

Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma [Completed]

Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG [Completed]

Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia [Completed]

Phase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG) [Completed]

Therapeutic Effect and Safety of Combined Hydroxyurea With Recombinant Human Erythropoietin. [Not yet recruiting]

Phase II Study of GIVINOSTAT (ITF2357) in Combination With Hydroxyurea in Polycythemia Vera [Completed]

Realizing Effectiveness Across Continents With Hydroxyurea (REACH) [Recruiting]

Sickle Cell Disease - Stroke Prevention in Nigeria Trial [Active, not recruiting]

Inflammatory Response to Hydroxyurea Therapy in Sickle Cell Disease [Completed]

Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma [Completed]

Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET) [Recruiting]

Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma [Completed]

Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease [Recruiting]

Efficacy and Safety of Imatinib Mesylate Plus Hydroxyurea (HU) in Patients With Recurrent Glioblastoma Multiforme (GBM) [Terminated]

Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea [Active, not recruiting]

A Study of Low Dose Interferon Alpha Versus Hydroxyurea in Treatment of Chronic Myeloid Neoplasms [Recruiting]

A Dose Escalation Study of Hydroxyurea in Combination With SCH900776 in Advanced Malignant Solid Tumors [Withdrawn]

Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment [Enrolling by invitation]

Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer [Completed]

Therapeutic Response Evaluation and Adherence Trial (TREAT) [Recruiting]

Hydroxyurea in Pulmonary Arterial Hypertension [Withdrawn]

Pegylated Interferon Alpha-2b Versus Hydroxyurea in Polycythemia Vera [Active, not recruiting]

Novel Dose Escalation to Predict Treatment With Hydroxyurea [Recruiting]

Randomized Phase III Study of Decitabine +/- Hydroxyurea (HY) Versus HY in Advanced Proliferative CMML [Recruiting]

Novel Use Of Hydroxyurea in an African Region With Malaria [Recruiting]

Sparing Conversion to Abnormal TCD (Transcranial Doppler) Elevation (SCATE) [Terminated]

Hydroxyurea in Young Children With Sickle Cell Anemia [Completed]

Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT [Recruiting]

Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease [Active, not recruiting]

Primary Thrombocythaemia 1 Trial [Active, not recruiting]

Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major [Completed]

Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia [Completed]

Stroke With Transfusions Changing to Hydroxyurea [Terminated]

Hydroxyurea in Primary Progressive Multiple Sclerosis [Terminated]

Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators [Recruiting]

The Safety and Effectiveness of Hydroxyurea and ddI Used Individually or Together in HIV-Infected Patients [Completed]

S9811 Hydroxyurea in Treating Patients With Unresectable Benign Meningioma [Completed]

Hydroxyurea With or Without Imatinib Mesylate in Treating Patients With Recurrent or Progressive Meningioma [Recruiting]

Effectiveness of Early or Delayed Addition of Hydroxyurea to a Three-Drug Anti-HIV Drug Combination Including Didanosine, in Advanced HIV Patients Who Failed a First or Second Anti-HIV Triple-Drug Therapy [Withdrawn]

Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease [Terminated]

Effect of Hydroxyurea as Treatment for Primary Desmoid Tumors [Withdrawn]

Treatment of Hemoglobin SC Disease [Recruiting]

Future of Spermatogenesis in Men With Sickle Cell Disease Medically Treated [Completed]

Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease [Recruiting]

Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia [Completed]

Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension [Terminated]

Homoharringtonine Compared With Hydroxyurea for Chronic Myelogenous Leukemia That Has Not Responded to Interferon Alfa [Terminated]

Safety and Effectiveness of an Anti-HIV Drug Combination With and Without Hydroxyurea in Patients With Early HIV Infection [Withdrawn]

A Randomized, Placebo-Controlled Study of the Safety and Efficacy of Efavirenz, Didanosine, and Stavudine in Combination With or Without Hydroxyurea in Antiretroviral Naive or Experienced HIV-Infected Patients [Completed]

Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease [Completed]

A Study of the Safety and Effectiveness of Hydroxyurea in Patients on Potent Antiretroviral Therapy and Who Have Less Than 200 Copies/ml of HIV RNA in Their Blood [Completed]

Treatment of CML Patients With Imatinib and Hydroxyurea (CML2004) [Completed]

Combination of Hydroxyurea and Verapamil for Refractory Meningiomas [Active, not recruiting]

Phase II of Chemotherapy for Relapsed Epstein Barr Virus Associated Lymphoma [Recruiting]

A Study of Anagrelide and Hydroxyurea in High-Risk Essential Thrombocythemia Patients [Active, not recruiting]

Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS (DARH) [Not yet recruiting]

Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea [Completed]

Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia) [Completed]

Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia [Completed]

Hydroxyurea to Prevent Stroke in Children With Sickle Cell Anemia and Elevated TCD Flow Velocity [Completed]

A Study of Chemoradiotherapy for Intermediate Stage/Selected Stage IV Cancers of the Head and Neck [Completed]

Safety and Effectiveness of Combining Hydroxyurea (HU) With Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults [Completed]

A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Recent HIV Infection [Completed]

Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia [Completed]

Hydroxyurea in Treating Patients With Epstein-Barr Virus-Associated Primary CNS Lymphoma and AIDS [Completed]

A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Early Asymptomatic HIV Infection [Completed]

Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol [Enrolling by invitation]

Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH) [Completed]

Hydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma [Active, not recruiting]

Hydroxyurea Plus Combination Chemotherapy in Patients With Non-small Cell Lung Cancer [Active, not recruiting]

A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients [Completed]

A Pilot Therapeutic Trial Using Hydroxyurea in Type II and Type III Spinal Muscular Atrophy Patients [Active, not recruiting]

A Trial of Hydroxyurea in Spinal Muscular Atrophy [Completed]

Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study) [Enrolling by invitation]

PHASE III TRIAL COMPARING, NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY VERSUS THE SAME NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY ASSOCIATED WITH DAILY HYDROXYUREA IN THE TREATMENT OF LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE. [Active, not recruiting]

Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial) [Active, not recruiting]

Adherence to Hydroxyurea in Children With Sickle Cell Anemia [Completed]

A Study of MKC-442 in Combination With Other Anti-HIV Drugs [Completed]

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment [Completed]

Phase 2 Study of Montelukast for the Treatment of Sickle Cell Anemia [Recruiting]

Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer [Recruiting]

Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer [Completed]

Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises [Active, not recruiting]

Safety and Durability ofTenofovir and a Cell Cycle Agent for Viral Suppression [Completed]

Risk-based Therapy for Sickle Cell Anemia: A Feasibility Study [Terminated]

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer [Recruiting]

Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG) [Completed]

Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Locally Advanced Head & Neck Cancer [Active, not recruiting]

Combination Drug Treatment of Pediatric HIV Infection [Completed]

Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes [Completed]

Radiation Therapy in Treating Patients With Glioblastoma [Completed]

Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia [Completed]

Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy. [Active, not recruiting]

TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea [Recruiting]

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