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Hydromorphone (Hydromorphone Hydrochloride) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The major hazards of hydromorphone hydrochloride tablets include respiratory depression and apnea. To a lesser degree, circulatory depression, respiratory arrest, shock and cardiac arrest have occurred.

The most frequently observed adverse effects are light-headedness, dizziness, sedation, nausea, vomiting, sweating, flushing, dysphoria, euphoria, dry mouth, and pruritus. These effects seem to be more prominent in ambulatory patients and in those not experiencing severe pain.

Less Frequently Observed with Opioid Analgesics

General and CNS

Weakness, headache, agitation, tremor, uncoordinated muscle movements, alterations of mood (nervousness, apprehension, depression, floating feelings, dreams), muscle rigidity, paresthesia, muscle tremor, blurred vision, nystagmus, diplopia and miosis, transient hallucinations and disorientation, visual disturbances, insomnia, increased intracranial

Cardiovascular

Flushing of the face, chills, tachycardia, bradycardia, palpitation, faintness, syncope, hypotension, hypertension

Respiratory

Bronchospasm and laryngospasm

Gastrointestinal

Constipation, biliary tract spasm, ileus, anorexia, diarrhea, cramps, taste alteration

Genitourinary

Urinary retention or hesitancy, antidiuretic

Dermatologic

Urticaria, other skin rashes, diaphoresis.



REPORTS OF SUSPECTED HYDROMORPHONE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Hydromorphone. The information is not vetted and should not be considered as verified clinical evidence.

Possible Hydromorphone side effects / adverse reactions in 25 year old female

Reported by a physician from United States on 2011-12-22

Patient: 25 year old female

Reactions: Completed Suicide

Adverse event resulted in: death

Suspect drug(s):
Acetaminophen and Hydrocodone Bitartrate
    Administration route: Oral

Alprazolam
    Administration route: Oral

Acetaminophen
    Administration route: Oral

Lorazepam
    Administration route: Oral

Hydromorphone
    Administration route: Oral



Possible Hydromorphone side effects / adverse reactions in 19 year old female

Reported by a physician from United States on 2012-01-04

Patient: 19 year old female

Reactions: Intentional Overdose, Completed Suicide

Adverse event resulted in: death

Suspect drug(s):
Acetaminophen

Hydrocodone

Hydromorphone

Ibuprofen
    Dosage: 200 mg (max 500 tablets)
    Administration route: Oral

Acetylsalicylic Acid SRT
    Dosage: 325 mg (max 100 tablets)
    Administration route: Oral

Acetaminophen and Hydrocodone Bitartrate
    Dosage: (max 30 tablets)
    Administration route: Oral



Possible Hydromorphone side effects / adverse reactions in 42 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-12

Patient: 42 year old female

Reactions: Death

Adverse event resulted in: death

Suspect drug(s):
Omeprazole
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Ondansetron
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Hydromorphone
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Amitriptyline HCL
    Dosage: unk
    Administration route: Oral

Verapamil HCL
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



See index of all Hydromorphone side effect reports >>

Drug label data at the top of this Page last updated: 2007-01-11

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