SUMMARY
HYDROCORTISONE AND ACETIC ACID OTIC SOLUTION, USP
Hydrocortisone and Acetic Acid Otic Solution, USP is a solution containing hydrocortisone (1%) and acetic acid (2%), in a propylene glycol vehicle containing propylene glycol diacetate (3%), benzethonium chloride (0.02%), sodium acetate (0.015%) and citric acid.
Hydrocortisone and Acetic Acid (hydrocortisone/acetic acid OTIC) is indicated for the following:
For the treatment of superficial infections of the external auditory canal caused by organisms susceptible to the action of the antimicrobial, complicated by inflammation.
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NEWS HIGHLIGHTSMedia Articles Related to Hydrocortisone and Acetic Acid (Hydrocortisone / Acetic Acid Otic)
Lung Inflammation Caused By Ubiquitous Engineered Nanomaterials
Source: Respiratory / Asthma News From Medical News Today [2013.05.09]
A consortium of scientists from across the country has found that breathing ultrafine particles from a large family of materials that increasingly are found in a host of household and commercial products, from sunscreens to the ink in copy machines to super-strong but lightweight sporting equipment, can cause lung inflammation and damage...
Researchers Have Discovered Synthetic Agents Used To Treat HIV Inflammation
Source: HIV / AIDS News From Medical News Today [2013.05.07]
HIV can cause serious inflammation, regardless of drug therapy, as it develops slowly in immune cells called macrophages...
Single Session Of Relaxation Response Practice Alters Gene Expression Involved In Inflammation, Energy Metabolism, Insulin Secretion
Source: Anxiety / Stress News From Medical News Today [2013.05.03]
A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) finds that elicitation of the relaxation response - a physiologic state of deep rest induced by practices such as meditation, yoga, deep breathing and prayer - produces immediate changes in the expression of...
Key Initiator To Prion And Parkinson's Disease Is Likely Brain Inflammation
Source: CJD / vCJD / Mad Cow Disease News From Medical News Today [2012.12.03]
Prion diseases represent a family of neurodegenerative disorders associated with the loss of brain cells and caused by proteins called prions (derived from 'protein' and 'infection'). The diseases are found in both humans and animals, such as Creutzfeld-Jakob disease and mad cow disease respectively...
A Molecule Found That Puts The Brakes On Inflammation
Source: Lupus News From Medical News Today [2012.10.02]
We couldn't live without our immune systems, always tuned to detect and eradicate invading pathogens and particles. But sometimes the immune response goes overboard, triggering autoimmune diseases like lupus, asthma or inflammatory bowel disease...
Published Studies Related to Hydrocortisone and Acetic Acid (Hydrocortisone / Acetic Acid Otic)
Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. [1991.08.08]
We have previously shown that chronic sucralfate ingestion stimulates gastric epithelial proliferation in rats, which may explain one of the beneficial effects of sucralfate in healing of peptic ulcers. In a separate study, we have found that chronic steroid administration delays the healing of experimental gastric ulcers in rats...
Effects of prostaglandins on hydrocortisone-induced delayed healing of chronic gastric ulcers in the rat. [1991]
We have previously shown that chronic steroid administration delays the healing of experimental gastric ulcers in rats. This study was designed to test the beneficial effects of 16,16-dimethylprostaglandin E2 or TRY-200, a stable prostaglandin I2 analogue, on the delayed healing by hydrocortisone (HC) of chronic gastric ulcers in rats...
Kinetics of drug release from polylactic acid-hydrocortisone microcapsules. [1986.07]
Polylactic acid microcapsules of similar particle size distribution containing various drug loadings of hydrocortisone were prepared. The microcapsules, which contained randomly dispensed drug particles, showed a dissolution pattern which consists of a fast first-stage and a slow second-stage drug release.
Clinical Trials Related to Hydrocortisone and Acetic Acid (Hydrocortisone / Acetic Acid Otic)
Contribution of Salivary Cortisol in the Detection of Infra-clinic Cortisol Adenoma (ACIC) [Recruiting]
Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response? [Active, not recruiting]
The primary purpose of this study is to examine whether IV hydrocortisone can speed up the
time required for Venlafaxine XR to work.
Trial of Hydrocortisone for Post-Traumatic Stress Disorder (PTSD) [Recruiting]
Developing novel and effective pharmacologic interventions for this post-traumatic stress
disorder is important. The investigators propose to replicate findings of an earlier
published pilot study using low dose hydrocortisone as a treatment for PTSD. In order to do
so in a more meaningful way, the investigators will conduct a larger but similar randomized
double-blind placebo-controlled, cross-over design treatment study examining the use of low
dose hydrocortisone (or placebo) for 4 weeks in combat veterans suffering from PTSD.
The investigators hypothesize that, as described by Aerni et al. (2004), administration of
daily hydrocortisone will lead to a reduction in PTSD symptom severity, but particularly for
re-experiencing types (e. g., flashbacks, nightmares)of symptoms. The investigators also hope
to examine potential predictors and moderators of treatment response based on subjects'
clinical characteristics, as well as serum cortisol and ACTH levels.
Pharmacokinetics of Hydrocortisone After Subcutaneous Administration in Chronic Adrenal Insufficiency [Not yet recruiting]
Patients with chronic adrenal insufficiency need to adapt their hydrocortisone replacement
dose in conditions of physical or psychological stress to prevent life threatening adrenal
crisis. In cases of more severe impairment or unsecure gastrointestinal absorption (e. g.
gastroenteritis, severe infectious disease), parenteral administration of the hydrocortisone
dose is crucial. The study is conducted to offer patients the possibility to perform
hydrocortisone self administration in emergency situations in a way of administration which
is easy to perform and accepted by the patient. Therefore, pharmacokinetics and safety of
subcutaneous hydrocortisone administration will be studied and compared to intramuscular
administration.
Efficacy Study of Low-Dose Hydrocortisone Treatment for Fibromyalgia [Completed]
This study is based on clinical findings that some patients with fibromyalgia have a tendency
towards lower levels of the stress hormone cortisol. The hypothesis to be tested in this
study is that the administration of a very low-dose of cortisol which has no side effects
corrects this deficiency and results in an improvement of symptoms
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