ADVERSE REACTIONS
Central Nervous System
Sedation, drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, dizziness, psychic dependence, mood changes.
Gastrointestinal System
Nausea and vomiting may occur; they are more frequent in ambulatory than in recumbent patients. Prolonged administration of HYCODAN may produce constipation.
Genitourinary System
Ureteral spasm, spasm of vesicle sphincters and urinary retention have been reported with opiates.
Respiratory Depression
HYCODAN may produce dose-related respiratory depression by acting directly on brain stem respiratory centers (see OVERDOSAGE).
Dermatological
Skin rash, pruritus.
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