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Hycodan (Hydrocodone Bitartrate / Homatropine Methylbromide) - Summary

 


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HYCODAN SUMMARY

ANTITUSSIVE

HYCODAN®
(Hydrocodone Bitartrate and Homatropine Methylbromide)
TABLETS AND SYRUP

CIII

Rx only

HYCODAN contains hydrocodone (dihydrocodeinone) bitartrate, a semisynthetic centrally-acting opioid antitussive. Homatropine methylbromide is included in a subtherapeutic amount to discourage deliberate overdosage.

HYCODAN (hydrocodone bitartrate and homatropine methylbromide) is indicated for the symptomatic relief of cough.


See all Hycodan indications & dosage >>

HYCODAN NEWS HIGHLIGHTS

Media Articles Related to Hycodan (Hydrocodone / Homatropine)

Unvaccinated Kids Getting Whooping Cough
Source: MedicineNet Pertussis Specialty [2009.05.26]
Title: Unvaccinated Kids Getting Whooping Cough
Category: Health News
Created: 5/26/2009
Last Editorial Review: 5/26/2009

Earlier Vaccination Could Cut Whooping Cough Deaths
Source: MedicineNet Pertussis Specialty [2008.11.04]
Title: Earlier Vaccination Could Cut Whooping Cough Deaths
Category: Health News
Created: 11/4/2008 2:00:00 AM
Last Editorial Review: 11/4/2008

Cover Your Cough!
Source: MedicineNet Severe Acute Respiratory Syndrome (SARS) Specialty [2008.10.07]
Title: Cover Your Cough!
Category: Health Fact Tool
Created: 11/15/2004
Last Editorial Review: 10/7/2008

Chronic Cough
Source: MedicineNet Alpha 1 Antitrypsin Deficiency Specialty [2007.12.07]
Title: Chronic Cough
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 12/7/2007

What Is Croup? What Causes Croup?
Source: Respiratory / Asthma News From Medical News Today [2009.07.01]
Croup is a common respiratory condition characterized by inflammation of the upper airways that often occurs in infants and children. The result is a swelling and narrowing of the larynx (voice box) and trachea (wind pipe) that results in a harsh, barking cough. Although croup is usually not a serious condition, it can be scary for children and parents. When combined with breathing difficulties, croup can become a severe and life-threatening condition.

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Published Studies Related to Hycodan (Hydrocodone / Homatropine)

Hydrocodone/acetaminophen and tramadol chlorhydrate combination tablets for the management of chronic cancer pain: a double-blind comparative trial. [2008.01]
OBJETIVES: The purpose of this study was to compare the analgesic efficacy and tolerability of opioids hydrocodone and tramadol in the relief of cancer pain... CONCLUSIONS: There was no superior analgesic efficacy with the administration of hydrocodone/acetaminophen when compared to patients receiving tramadol in the relief of cancer pain. Tramadol produced more mild side effects than hydrocodone.

Tramadol/acetaminophen or hydrocodone/acetaminophen for the treatment of ankle sprain: a randomized, placebo-controlled trial. [2007.04]
STUDY OBJECTIVE: This randomized, multicenter study compares the analgesic efficacy and safety of tramadol/acetaminophen versus hydrocodone/acetaminophen versus placebo for the treatment of acute musculoskeletal pain caused by ankle sprain... CONCLUSION: One or 2 capsules of 37.5 mg tramadol/325 mg acetaminophen and 1 capsule of 7.5 mg hydrocodone/650 mg acetaminophen were well tolerated, had comparable clinical utility, and were more effective than placebo in the management of acute musculoskeletal pain caused by ankle sprain.

Tramadol/Acetaminophen or Hydrocodone/Acetaminophen for the Treatment of Ankle Sprain: A Randomized, Placebo-Controlled Trial. [2006.11.17]
STUDY OBJECTIVE: This randomized, multicenter study compares the analgesic efficacy and safety of tramadol/acetaminophen versus hydrocodone/acetaminophen versus placebo for the treatment of acute musculoskeletal pain caused by ankle sprain... CONCLUSION: One or 2 capsules of 37.5 mg tramadol/325 mg acetaminophen and 1 capsule of 7.5 mg hydrocodone/650 mg acetaminophen were well tolerated, had comparable clinical utility, and were more effective than placebo in the management of acute musculoskeletal pain caused by ankle sprain.

A comparison of the abuse liability of tramadol, NSAIDs, and hydrocodone in patients with chronic pain. [2006.05]
Concern about abuse/dependence in chronic pain patients taking opioid analgesics may lead to undertreatment of pain, yet little is known about the prevalence of abuse/dependence in these patients and how it differs among analgesic agents. The objective of this study was to assess the prevalence of tramadol abuse compared to nonsteroidal anti-inflammatory drugs (NSAIDs) and hydrocodone-containing analgesics in patients with chronic noncancer pain (CNP).

Rofecoxib versus hydrocodone/acetaminophen for postoperative analgesia in functional endoscopic sinus surgery. [2006.04]
OBJECTIVES/HYPOTHESIS: Functional endoscopic sinus surgery (FESS) is less invasive and more tissue sparing than extirpative techniques, with an assumed benefit of diminished postoperative pain. Oral opioids are commonly prescribed after sinus surgery but are associated with adverse effects, including gastrointestinal and neurologic symptoms. Nonopioid analgesics have been suggested to offer similar pain control efficacy with fewer adverse effects. STUDY DESIGN: To investigate postoperative analgesia in FESS, a prospective randomized, double-blinded comparison of hydrocodone/acetaminophen 7.5/750 mg (an opioidderivative) with rofecoxib 50 mg (a cyclooxygenase-2 inhibitor) was performed... CONCLUSIONS: The use of nonopioid analgesics after FESS may provide similar pain control to oral opioids.

more studies >>

Clinical Trials Related to Hycodan (Hydrocodone / Homatropine)

A CCRC Study: A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine [Active, not recruiting]

A Study Comparing VicodinŽ CR and NORCOŽ to Placebo in Subjects With Acute Pain Following Bunionectomy [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of Extended Release Hydrocodone/Acetaminophen and Immediate Release Hydrocodone/Acetaminophen with placebo over a 12 hour dosing period in patients who have had a bunionectomy, and to assess the safety of the drug for 7 days after patients are discharged from the hospital.

A Study Comparing the Analgesic Activity of Extended Release Hydrocodone/Acetaminophen (VicodinŽ CR) and Placebo in Subjects With Pain Following Bunionectomy Surgery [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of 2 different dose levels of Extended Release Hydrocodone/Acetaminophen with placebo over a 48 hour dosing period in patients who have had bunionectomy surgery, and to assess the safety of the drug for 7 days after patients are discharged from the hospital.

A Study Comparing the Analgesic Efficacy and Safety of Extended Release Hydrocodone/Acetaminophen (VicodinŽ CR)and Placebo in Subjects With Osteoarthritis [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of Extended Release Hydrocodone/Acetaminophen with placebo over a 5-week dosing period in patients with osteoarthritis.

A Study of Extended-Release Hydrocodone/Acetaminophen (Vicodin CRŽ) in Subjects With Acute Pain Following Bunionectomy [Completed]
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of Extended-Release Hydrocodone/Acetaminophen compared to placebo over a 48 hour dosing period in patients who have had bunionectomy surgery and to assess the safety of the drug for 7 days after patients are discharged from the hospital.

more trials >>

Page last updated: 2009-07-01

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