News related to Humira (Adalimumab) and/or conditions it is approved for
New Data Suggest Initial Use Of Abbott's HUMIRA® (adalimumab) May Help Prevent Further Joint Damage For Up To Five Years
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.08]
New data show half of patients with moderate to severe early rheumatoid arthritis showed no progression of joint damage at five years. These results were seen in patients who initially received HUMIRA® (adalimumab) in combination with methotrexate (MTX) for two years and continued on HUMIRA for an additional three years in an open-label extension study. These results were presented this week at the American College of Rheumatology annual meeting in San Francisco.
Humira receives FDA approval for psoriatic arthritis
Source: The Doctors Lounge - Rheumatology
The FDA approved HUMIRA® (adalimumab) for reducing signs and symptoms of active arthritis in patients with psoriatic arthritis.
Adalimumab May Reduce Health-Care Costs For Crohn's Disease Patients
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2008.11.14]
Additional study shows further research needed on 5-ASA's chemopreventative role in ulcerative colitis Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD). IBD occurs most frequently in people in their late teens and twenties. There have been cases in children as young as two years old and in older adults in their seventies and eighties; men and women have an equal chance of getting the disease.
Adalimumab plus methotrexate effective for rheumatoid arthritis
Source: The Doctors Lounge - Rheumatology
Adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.
Vitamin E won't prevent rheumatoid arthritis: study (Reuters)
Source: Y! Health Arthritis News [2008.11.20]
Reuters - Taking vitamin E supplements does not reduce a woman's risk of rheumatoid arthritis (RA), an analysis of data from the Women's Health Study indicates.
Rheumatoid Arthritis - Cimzia(R) Studies Show Significant Clinical Benefits For Mono- And Combination Therapy
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.18]
UCB today announced the results of two phase III studies, published in the Annals of the Rheumatic Diseases Online, showing Cimzia® (certolizumab pegol), the only PEGylated anti-TNFalpha (Tumour Necrosis Factor alpha), provided significant clinical benefits as monotherapy, and in combination with methotrexate, in adults with active rheumatoid arthritis (RA).
New Data Points To Long Lasting Beneficial Effects Of CEL-SCI's Rheumatoid Arthritis Vaccine
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.15]
CEL-SCI Corporation (NYSE: CVM) announced the presentation of new rheumatoid arthritis data at the 6th annual GTCbio Vaccine Conference in Vienna, Va. The data, presented by Dr. Daniel Zimmerman, Senior Vice President of Research, Cellular Immunology of CEL-SCI, indicate that CEL-SCI's rheumatoid arthritis treatment vaccine CEL-2000 prevents or retards the permanent tissue damage caused by rheumatoid arthritis.
Rheumatoid Arthritis Exercises Slideshow
Source: MedicineNet Arthritis Specialty [2008.11.14]
Title: Rheumatoid Arthritis Exercises Slideshow
Category: Slideshows
Created: 11/13/2008
Last Editorial Review: 11/14/2008
Rheumatoid Arthritis Pictures Slideshow
Source: MedicineNet Arthritis Specialty [2008.11.13]
Title: Rheumatoid Arthritis Pictures Slideshow
Category: Slideshows
Created: 11/10/2008
Last Editorial Review: 11/13/2008
Rheumatoid Arthritis Breakthrough - Plos Biology
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.11]
Rheumatoid arthritis is a painful, inflammatory type of arthritis that occurs when the body's immune system attacks itself. A new paper, published in this week's issue of PLoS Biology, reports a breakthrough in the understanding of how autoimmune responses can be controlled, offering a promising new strategy for therapy development for rheumatoid arthritis.
New Data Shows ACTEMRA Inhibits Progression Of Joint Destruction And Improves Physical Function Of Patients With Rheumatoid Arthritis
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.06]
Roche announced that the innovative new therapy ACTEMRA (tocilizumab) can significantly inhibit structural damage to joints in patients with rheumatoid arthritis (RA) this is a critical measure of effectiveness of an RA treatment. ACTEMRA was also found to improve the patients' physical function after one year of therapy and to significantly increase the disease remission rate.
New Therapeutic Target Identified For Rheumatoid Arthritis
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.06]
Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis. The study, published online ahead of print, will appear Nov. 14 in the journal Immunity.
Alternative Dosing Should Be Considered Due To Wide Variability In Rheumatoid Arthritis Drug
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.05]
Methotrexate (MTX) is commonly used to treat rheumatoid arthritis (RA) and is suggested as the "anchor" drug in treating the disease. Despite its widespread use, the understanding of its mechanism of action and pharmacokinetics is limited. Since joint damage occurs early in the course of RA and is largely irreversible, understanding the time it takes for stable levels of MTX to be reached could be useful in effectively controlling RA and preventing long-term damage.
Wide Variation In Medicaid Policies For Rheumatoid Arthritis Drugs
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.05]
Patients with inflammatory diseases such as rheumatoid arthritis now have many more treatment options than in the past, including biologic disease-modifying antirheumatic drugs (DMARDs). These drugs, derived by modifying substances found in humans or animals, slow progression of the disease rather than simply treating the symptoms. The cost of biologic DMARDs is a major concern because a one month's supply may cost 100 times more than a year's supply of older, non-biologic DMARDs.
Antiangiogenic Role Of 2ME2 Demonstrated In Rheumatoid Arthritis Models
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.04]
EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, announced the publication of preclinical results for 2ME2 (Panzem(R) or 2- methoxyestradiol) in rheumatoid arthritis (RA). The results of the study, conducted by EntreMed collaborator, Dr.
Predicting Depression In People With Rheumatoid Arthritis
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.03]
Disability and a recent diagnosis of rheumatoid arthritis (RA) are associated with a greater risk for depression according to research funded by the Arthritis Foundation and presented this week at the American College of Rheumatology Annual Scientific Meeting in San Francisco. Studies show that people with RA who are depressed have worse outcomes - including death - as compared to people with RA who are not depressed.
Yoga Helpful For People With Rheumatoid Arthritis
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.03]
A program of yoga poses, breathing and relaxation significantly reduces joint tenderness and swelling for people with rheumatoid arthritis (RA), according to research funded in part by the Arthritis Foundation and presented this week at the American College of Rheumatology Annual Scientific Meeting in San Francisco.
ACR: Biologics Seen Safe for Long-Term Use in Juvenile Rheumatoid Arthritis
Source: MedPage Today Rheumatology [2008.10.30]
SAN FRANCISCO (MedPage Today) -- Long-term, continuous use of biologics may be safe for children with rheumatoid arthritis, according to two studies reported here.
ACR: Short-Term Biologics Early in Rheumatoid Arthritis May Have Longer-Term Benefits
Source: MedPage Today Rheumatology [2008.10.30]
SAN FRANCISCO (MedPage Today) -- Incorporating biologics into treatment early in the course of rheumatoid arthritis may keep symptoms at bay for years or even indefinitely, researchers found.
Rheumatoid arthritis on the rise in women: study (Reuters)
Source: Y! Health Arthritis News [2008.10.30]
Reuters - After 40 years of decline, the incidence of rheumatoid arthritis appears to be on the rise among women, according to research conducted at the Mayo Clinic in Rochester, Minnesota.
Gum disease common with rheumatoid arthritis (Reuters)
Source: Y! Health Oral Care News [2008.10.30]
Reuters - Symptoms of gum disease are common in patients with rheumatoid arthritis (RA) and may be an independent marker of RA disease activity, according to research presented this week at the American College of Rheumatology meeting in San Francisco.
ACR: No Cancer Risk with TNF-Inhibitors for Rheumatoid Arthritis
Source: MedPage Today Rheumatology [2008.10.29]
SAN FRANCISCO (MedPage Today) -- Biologic therapies for rheumatoid arthritis do not increase cancer risks despite concerns that inhibiting tumor necrosis factor has that potential, Spanish researchers found.
Biologics Don't Raise Cancer Risk in Rheumatoid Arthritis Patients
Source: MedicineNet Arthritis Specialty [2008.10.29]
Title: Biologics Don't Raise Cancer Risk in Rheumatoid Arthritis Patients
Category: Health News
Created: 10/29/2008 2:00:00 AM
Last Editorial Review: 10/29/2008
Rheumatoid Arthritis May Harm Gums
Source: MedicineNet Dental Injuries Specialty [2008.10.29]
Title: Rheumatoid Arthritis May Harm Gums
Category: Health News
Created: 10/29/2008 2:00:00 AM
Last Editorial Review: 10/29/2008
ACR: Rheumatoid Arthritis Comparable to Diabetes for Heart Risk
Source: MedPage Today Rheumatology [2008.10.28]
SAN FRANCISCO (MedPage Today) -- Rheumatoid arthritis independently raises the risks of cardiovascular disease and heart attacks to the level of diabetes, two research groups reported here.
Rheumatoid Arthritis May Harm Gums (HealthDay)
Source: Y! Health Arthritis News [2008.10.28]
HealthDay - TUESDAY, Oct. 28 (HealthDay News) -- Rheumatoid arthritis (RA)
may increase the risk of gum disease, a U.S. study finds.
Biologics Don't Raise Cancer Risk in Rheumatoid Arthritis
Patients (HealthDay)
Source: Y! Health Arthritis News [2008.10.28]
HealthDay - TUESDAY, Oct. 28 (HealthDay News) -- TNF-antagonists, drugs
widely used to treat rheumatoid arthritis (RA), don't appear to cause
cancer, say Spanish researchers who analyzed data on more than 4,000 RA
patients treated with the biologics.
Rheumatoid Arthritis Rising Among U.S. Women
Source: MedicineNet Arthritis Specialty [2008.10.28]
Title: Rheumatoid Arthritis Rising Among U.S. Women
Category: Health News
Created: 10/28/2008 2:00:00 AM
Last Editorial Review: 10/28/2008
Rheumatoid Arthritis a Threat to the Heart
Source: MedicineNet Rheumatoid Arthritis Specialty [2008.10.28]
Title: Rheumatoid Arthritis a Threat to the Heart
Category: Health News
Created: 10/28/2008 2:00:00 AM
Last Editorial Review: 10/28/2008
Rheumatoid Arthritis Rising Among U.S. Women (HealthDay)
Source: Y! Health Arthritis News [2008.10.27]
HealthDay - MONDAY, Oct. 27 (HealthDay News) -- The number of American women
with rheumatoid arthritis (RA) is growing again after four decades of
decline, according to a Mayo Clinic study.
Rheumatoid Arthritis a Threat to the Heart (HealthDay)
Source: Y! Health Arthritis News [2008.10.27]
HealthDay - MONDAY, Oct. 27 (HealthDay News) -- People newly diagnosed with
rheumatoid arthritis face twice the risk of a heart attack, and those who
do suffer a heart attack tend to have more heart-related complications,
new research says.
Drug Combo Fights Rheumatoid Arthritis
Source: MedicineNet etanercept Specialty [2008.07.16]
Title: Drug Combo Fights Rheumatoid Arthritis
Category: Health News
Created: 7/16/2008
Last Editorial Review: 7/16/2008
Females With High Birth Weight More Likely To Develop Rheumatoid Arthritis
Source: Body Aches News From Medical News Today [2008.07.01]
A new study published in the Annals of the Rheumatic Diseases finds that compared to females born with average birth weight, those born with heavy birth weight are two times as likely to develop rheumatoid arthritis when they become adults. Rheumatoid arthritis is a condition that occurs when the immune system attacks the joints, lungs or skin and results in inflammation, pain, and loss of functioning mobility.
Rheumatoid Arthritis Treatment Guidelines Updated
Source: MedicineNet adalimumab Specialty [2008.06.27]
Title: Rheumatoid Arthritis Treatment Guidelines Updated
Category: Health News
Created: 6/27/2008 2:00:00 AM
Last Editorial Review: 6/27/2008
Rheumatoid Arthritis Drug Boosts Melanoma Incidence
Source: MedicineNet methotrexate Specialty [2008.06.23]
Title: Rheumatoid Arthritis Drug Boosts Melanoma Incidence
Category: Health News
Created: 6/21/2008 2:00:00 AM
Last Editorial Review: 6/23/2008
Golimumab Eases Rheumatoid Arthritis Symptoms
Source: MedicineNet methotrexate Specialty [2008.06.12]
Title: Golimumab Eases Rheumatoid Arthritis Symptoms
Category: Health News
Created: 6/12/2008 2:00:00 AM
Last Editorial Review: 6/12/2008
Rheumatoid Arthritis
Source: MedicineNet Baker Cyst Specialty [2008.03.25]
Title: Rheumatoid Arthritis
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 3/25/2008
Juvenile Arthritis (Juvenile Rheumatoid Arthritis)
Source: MedicineNet Reactive Arthritis Specialty [2008.03.25]
Title: Juvenile Arthritis (Juvenile Rheumatoid Arthritis)
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 3/25/2008
Rheumatoid Arthritis Drugs May Lower Heart Attack, Stroke Risk
Source: MedicineNet leflunomide Specialty [2008.03.07]
Title: Rheumatoid Arthritis Drugs May Lower Heart Attack, Stroke Risk
Category: Health News
Created: 3/7/2008 2:00:00 AM
Last Editorial Review: 3/7/2008
Drug Combos Effective Against Rheumatoid Arthritis
Source: MedicineNet anakinra Specialty [2007.11.27]
Title: Drug Combos Effective Against Rheumatoid Arthritis
Category: Health News
Created: 11/27/2007 2:00:00 AM
Last Editorial Review: 11/27/2007
Rituximab Improves Symptoms of Rheumatoid Arthritis
Source: Medscape Pharmacotherapy Headlines [2004.06.16]
In a randomized, double-blind trial, a single course of two infusions of rituximab, alone or with cyclophosphamide or continued methotrexate, improved symptoms at weeks 24 and 48. (CME)
Medscape Medical News
Désirée Lie,Laurie Barclay
DMARDs May Protect Against Cardiovascular Disease in Rheumatoid Arthritis Patients
Source: Medscape Pharmacotherapy Headlines [2004.06.11]
Using U.S. health insurance claims, the investigators show a cardiac benefit for DMARDs and confirm potential harm from COX-2 inhibitors.
Medscape Medical News
Paula Moyer
The impact of smoking and genes on rheumatoid arthritis
Source: The Doctors Lounge - Orthopedics
New insight into the autoimmune triggers for rheumatoid arthritis among smokers with shared epitope genes.
The impact of smoking and genes on rheumatoid arthritis
Source: The Doctors Lounge - Rheumatology
New insight into the autoimmune triggers for rheumatoid arthritis among smokers with shared epitope genes.
Musculoskeletal Center Wins $2.2 Million For Drug Safety
Source: Arthritis / Rheumatology News From Medical News Today [2008.11.19]
The University of Alabama at Birmingham (UAB) Center for Education and Research on Therapeutics (CERTs) has won a $2.2 million federal grant to study the risks and benefits of a newer class of medicines called biologics. These are genetically engineered therapies that target the immune system of patients who have rheumatoid arthritis, Crohn's disease, psoriasis and other autoimmune disorders.
New Therapy Could Transform Arthritis Treatment (HealthDay)
Source: Y! Health Arthritis News [2008.11.13]
HealthDay - THURSDAY, Nov. 13 (HealthDay News) -- New understanding about how
to control autoimmune responses offers promise in efforts to develop
treatments for rheumatoid arthritis (RA), British researchers say.
Variable Oral Methotrexate Cell Concentrations in RA Confound Therapy
Source: MedPage Today Rheumatology [2008.11.11]
CHRISTCHURCH, New Zealand (MedPage Today) -- Wide variability in the way oral methotrexate accumulates and is eliminated makes monitoring and dosing decisions for rheumatoid arthritis patients difficult, a pharmacokinetic study found.
ACR: RA Incidence Trend Seen Rising, Particularly for Women
Source: MedPage Today Rheumatology [2008.10.28]
SAN FRANCISCO (MedPage Today) -- Rheumatoid arthritis rates may be rising for the first time in 40 years, driven by an increase among women, researchers found in a population-based cohort study.
B Cells Can Act Alone In Autoimmune Disease, Yale Researchers Report
Source: Lupus News From Medical News Today [2008.08.07]
B cells, the source of damaging autoantibodies, have long been thought to depend upon T cells for their activation and were not considered important in the initiation of autoimmune diseases like lupus or rheumatoid arthritis. In the Aug. 7 online issue of the journal of Immunity, Yale University researchers turn this paradigm on its head by showing that in systemic autoimmune diseases B cells can be activated the absence of T cells.
TNF-alpha Inhibition Shows Marked Benefits in Ankylosing Spondylitis
Source: Medscape Pharmacotherapy Headlines [2004.06.15]
Although reimbursement is less likely, benefits are more marked than in rheumatoid arthritis.
Medscape Medical News
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