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Humira (Adalimumab) - Published Studies

 


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Humira Related Published Studies

Well-designed clinical trials related to Humira (Adalimumab)

Effect of the early use of the anti-tumor necrosis factor adalimumab on the prevention of job loss in patients with early rheumatoid arthritis. [2008.10.15]

Beneficial effects of adalimumab on biomarkers reflecting structural damage in patients with ankylosing spondylitis. [2008.10]

Level of radiographic damage and radiographic progression are determinants of physical function: a longitudinal analysis of the TEMPO trial. [2008.09]

Adalimumab with or without methotrexate in juvenile rheumatoid arthritis. [2008.08.21]

Efficacy of adalimumab in the treatment of axial spondylarthritis without radiographically defined sacroiliitis: results of a twelve-week randomized, double-blind, placebo-controlled trial followed by an open-label extension up to week fifty-two. [2008.07]

Adalimumab reduces pain, fatigue, and stiffness in patients with ankylosing spondylitis: results from the adalimumab trial evaluating long-term safety and efficacy for ankylosing spondylitis (ATLAS). [2008.07]

Adalimumab Reduces Pain, Fatigue, and Stiffness in Patients with Ankylosing Spondylitis: Results from the Adalimumab Trial Evaluating Long-Term Safety and Efficacy for Ankylosing Spondylitis (ATLAS). [2008.05.15]

Impact of adalimumab treatment on health-related quality of life and other patient-reported outcomes: results from a 16-week randomized controlled trial in patients with moderate to severe plaque psoriasis. [2008.03]

Relative efficiencies of physician/assessor global estimates and patient questionnaire measures are similar to or greater than joint counts to distinguish adalimumab from control treatments in rheumatoid arthritis clinical trials. [2008.02]

Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial. [2008.01]

Impact of adalimumab treatment on health-related quality of life and other patient-reported outcomes: results from a 16-week randomized controlled trial in patients with moderate to severe plaque psoriasis. [2007.11.28]

The number needed to treat for adalimumab, etanercept, and infliximab based on ACR50 response in three randomized controlled trials on established rheumatoid arthritis: a systematic literature review. [2007.11]

Adalimumab plus methotrexate or standard therapy is more effective than methotrexate or standard therapies alone in the treatment of fatigue in patients with active, inadequately treated rheumatoid arthritis. [2007.11]

Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial. [2007.10.11]

Adalimumab for maintenance treatment of Crohn's disease: results of the CLASSIC II trial. [2007.09]

Health-related quality of life outcomes in patients with active ankylosing spondylitis treated with adalimumab: results from a randomized controlled study. [2007.08.15]

Health-related quality of life outcomes in patients with active ankylosing spondylitis treated with adalimumab: Results from a randomized controlled study. [2007.07.30]

Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial. [2007.06.19]

Adalimumab Induction Therapy for Crohn Disease Previously Treated with Infliximab. A Randomized Trial. [2007.04.30]

Adalimumab for long-term treatment of psoriatic arthritis: forty-eight week data from the adalimumab effectiveness in psoriatic arthritis trial. [2007.02]

Adalimumab treatment is associated with improvement in health-related quality of life in psoriasis: patient-reported outcomes from a phase II randomized controlled trial. [2007]

Clinical response to adalimumab treatment in patients with moderate to severe psoriasis: double-blind, randomized controlled trial and open-label extension study. [2006.10]

Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double-blind, placebo-controlled trial. [2006.07]

Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA 4 year extended study. [2006.06]

Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. [2006.02]

Safety Analyses of Adalimumab (HUMIRA(R)) in Global Clinical Trials and US Postmarketing Surveillance of Patients With Rheumatoid Arthritis. [2006.01.26]

The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. [2006.01]

Adalimumab for the treatment of patients with moderately to severely active psoriatic arthritis: results of a double-blind, randomized, placebo-controlled trial. [2005.10]

Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis. [2005]

Improvement in health utility among patients with rheumatoid arthritis treated with adalimumab (a human anti-TNF monoclonal antibody) plus methotrexate. [2004.06]

Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. [2004.05]

Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed. [2004.05]

Rapid alleviation of signs and symptoms of rheumatoid arthritis with intravenous or subcutaneous administration of adalimumab in combination with methotrexate. [2004]

Adalimumab, a fully human anti tumor necrosis factor-alpha monoclonal antibody, and concomitant standard antirheumatic therapy for the treatment of rheumatoid arthritis: results of STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis). [2003.12]

Efficacy and safety of the fully human anti-tumour necrosis factor alpha monoclonal antibody adalimumab (D2E7) in DMARD refractory patients with rheumatoid arthritis: a 12 week, phase II study. [2003.12]

Role of adalimumab in the treatment of early rheumatoid arthritis. [2003.09]

Efficacy, pharmacokinetic, and safety assessment of adalimumab, a fully human anti-tumor necrosis factor-alpha monoclonal antibody, in adults with rheumatoid arthritis receiving concomitant methotrexate: a pilot study. [2003.06]

Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. [2003.01]

A single dose, placebo controlled study of the fully human anti-tumor necrosis factor-alpha antibody adalimumab (D2E7) in patients with rheumatoid arthritis. [2002.11]

Well-designed clinical trials possibly related to Humira (Adalimumab)

Tumor necrosis factor antagonist responsiveness in a United States rheumatoid arthritis cohort. [2008.06]

Evaluation of the patient acceptable symptom state as an outcome measure in patients with ankylosing spondylitis: data from a randomized controlled trial. [2008.04.15]

Biologics for the treatment of juvenile idiopathic arthritis: a systematic review and critical analysis of the evidence. [2008.01]

Relationship between clinical response to therapy and health-related quality of life outcomes in patients with moderate to severe plaque psoriasis. [2008]

Targeting TNFalpha rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation. [2007.11]

[Rituximab in patients with rheumatoid arthritis: systematic review.] [2007.10.07]

Biologics for the treatment of juvenile idiopathic arthritis: a systematic review and critical analysis of the evidence. [2007.06.15]

Validation of the spondyloarthritis research consortium of Canada magnetic resonance imaging spinal inflammation index: is it necessary to score the entire spine? [2007.04.15]

The efficacy of anti-TNF in rheumatoid arthritis, a comparison between randomized controlled trials and clinical practice. [2007.04.10]

Steroid-resistant sarcoidosis: is antagonism of TNF-alpha the answer? [2007.03]

[The role of biological agents in the treatment of psoriatic arthritis, literature review] [2006.10.15]

The validity and responsiveness of three quality of life measures in the assessment of psoriasis patients: results of a phase II study. [2006.09.27]

[A comparison between the Simplified Disease Activity Index (SDAI) and the Disease Activity Score (DAS28) as measure of response to treatment in patients undergoing different therapeutic regimens] [2006.01]

Lefunomide in combination therapy. [2004.06]

Other research related to Humira (Adalimumab)

Effects of Adalimumab Maintenance Therapy on Health-Related Quality of Life of Patients With Crohn's Disease: Patient-Reported Outcomes of the CHARM Trial. [2008.10.03]

Immediate type I hypersensitivity response implicated in worsening injection site reactions to adalimumab. [2008.09]

Short-term influence of adalimumab on work productivity outcomes in patients with rheumatoid arthritis. [2008.09]

Adalimumab effectiveness for the treatment of ankylosing spondylitis is maintained for up to 2 years: long-term results from the ATLAS trial. [2008.08.13]

Adalimumab for long-term treatment of psoriatic arthritis: two-year data from the Adalimumab Effectiveness in Psoriatic Arthritis Trial (ADEPT). [2008.08.06]

Effects of Adalimumab Therapy on Incidence of Hospitalization and Surgery in Crohn's Disease: Results From the CHARM Study. [2008.08.03]

Short-term Influence of Adalimumab on Work Productivity Outcomes in Patients with Rheumatoid Arthritis. [2008.08.01]

A prospective, randomized, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: Effects of adalimumab treatment on synovial tissue. [2008.07.22]

Adalimumab for the treatment of Crohn's disease. [2008.07]

[The use of adalimumab in severe fistulising Crohn's disease] [2008.06.16]

Effectiveness of the combination of a whole-blood interferon-gamma assay and the tuberculin skin test in detecting latent tuberculosis infection in rheumatoid arthritis patients receiving adalimumab therapy. [2008.06.15]

Adalimumab therapy for refractory uveitis: a pilot study. [2008.06]

Exacerbation of psoriatic skin lesions in a patient with psoriatic arthritis receiving adalimumab. [2008.06]

Treating psoriasis with adalimumab. [2008.04]

Clinical investigation in highly disease-affected rheumatoid arthritis patients in Japan with adalimumab applying standard and general evaluation: the CHANGE study. [2008.03.12]

Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis. [2008.03]

Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION). [2008.03]

The use of adalimumab in the management of refractory Crohn's disease. [2008.02.15]

Organ-specific autoantibodies in patients with rheumatoid arthritis treated with adalimumab: a prospective long-term follow-up. [2008.02]

Personal and economic burden of late-stage rheumatoid arthritis among patients treated with adalimumab: an evaluation from a patient's perspective. [2008.02]

Adalimumab plus methotrexate improved SF-36 scores and reduced the effect of rheumatoid arthritis (RA) on work activity for patients with early RA. [2008.02]

[What is special about adalimumab?] [2008.02]

[Practical management of adalimumab] [2008.02]

[Safety of adalimumab] [2008.02]

[Efficacy of adalimumab] [2008.02]

Clinical remission and/or minimal disease activity in patients receiving adalimumab treatment in a multinational, open-label, twelve-week study. [2008.01.15]

Clinical and ultrasonographic monitoring of response to adalimumab treatment in rheumatoid arthritis. [2008.01]

Clinical remission and/or minimal disease activity in patients receiving adalimumab treatment in a multinational, open-label, twelve-week study. [2007.12.28]

Adalimumab plus Methotrexate Improved SF-36 Scores and Reduced the Effect of Rheumatoid Arthritis (RA) on Work Activity for Patients with Early RA. [2007.12.15]

Adalimumab effectively reduces the signs and symptoms of active ankylosing spondylitis in patients with total spinal ankylosis. [2007.12.04]

Adalimumab significantly reduces both spinal and sacroiliac joint inflammation in patients with ankylosing spondylitis: A multicenter, randomized, double-blind, placebo-controlled study. [2007.12]

Infliximab dose escalation vs. initiation of adalimumab for loss of response in Crohn's disease: a cost-effectiveness analysis. [2007.12]

Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION). [2007.11.28]

Adalimumab, etanercept and infliximab for the treatment of ankylosing spondylitis: a systematic review and economic evaluation. [2007.08]

Adalimumab for severe psoriasis and psoriatic arthritis: an open-label study in 30 patients previously treated with other biologics. [2007.08]

[Crohn's disease--infliximab, adalimumab and certolizumab-pegol: clinical value of anti-TNF-alpha treatment] [2007.08]

Effectiveness of adalimumab for rheumatoid arthritis in patients with a history of TNF-antagonist therapy in clinical practice. [2007.07]

[Fully human anti TNF-alpha monoclonal antibodies (adalimumab, golimumab)] [2007.07]

Safety and efficacy of adalimumab in treatment of patients with psoriatic arthritis who had failed disease modifying antirheumatic drug therapy. [2007.05]

Adalimumab induction therapy for ulcerative colitis with intolerance or lost response to infliximab: an open-label study. [2007.04.28]

Safety and Efficacy of Adalimumab in Treatment of Patients with Psoriatic Arthritis Who Had Failed Disease Modifying Antirheumatic Drug Therapy. [2007.04.15]

Adalimumab for the treatment of ankylosing spondylitis. [2007.04]

Adalimumab alone and in combination with disease- modifying antirheumatic drugs for the treatment of rheumatoid arthritis in clinical practice: The Research in Active Rheumatoid Arthritis (ReAct) trial. [2007.03.20]

Adalimumab maintenance therapy for Crohn's disease with intolerance or lost response to infliximab: an open-label study. [2007.03.15]

HUMIRA pen: a novel autoinjection device for subcutaneous injection of the fully human monoclonal antibody adalimumab. [2007.03]

Decrease of fructosamine levels during treatment with adalimumab in patients with both diabetes and rheumatoid arthritis. [2007.03]

Adalimumab in the therapy of uveitis in childhood. [2007.03]

Tuberculous peritonitis in a patient with rheumatoid arthritis treated with adalimumab. [2007.03]

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