Humatrope Related Published Studies
Well-designed clinical trials related to Humatrope (Somatropin)
Effect of the inhaled corticosteroid mometasone on small airway patency in patients with asthma. [2009.05]
Exercise capacity and hormonal response in adults with childhood onset growth hormone deficiency during long-term somatropin treatment. [1998.10]
Outcome of a four-year randomized study of daily versus three times weekly somatropin treatment in prepubertal naive growth hormone-deficient children. Genentech Study Group. [1996.05]
Well-designed clinical trials possibly related to Humatrope (Somatropin)
Addition of growth hormone to gonadotrophins in ovarian stimulation of poor responders treated by in-vitro fertilization: a systematic review and meta-analysis. [2009.11]
Improved thymic index, density and output in HIV-infected patients following low-dose growth hormone therapy: a placebo controlled study. [2009.10.23]
Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH. [2009.10]
Bone mineral density and effects of growth hormone treatment in prepubertal children with Prader-Willi syndrome: a randomized controlled trial. [2009.10]
Randomized Controlled Trial to Determine the Efficacy of Long-Term Growth Hormone Treatment in Severely Burned Children. [2009.09.02]
Growth hormone deficiency in patients with chronic heart failure and beneficial effects of its correction. [2009.09]
Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance. [2009.09]
Effects of growth hormone and free fatty acids on insulin sensitivity in patients with type 1 diabetes. [2009.09]
Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism. [2009.09]
Growth hormone receptor antagonist treatment reduces exercise performance in young males. [2009.09]
Peroxisome proliferator-activated receptor gamma (PPAR) agonism reduces the insulin-stimulated increase in circulating interleukin-6 in GH replaced GH-deficient adults. [2009.09]
Effects of differing antecedent increases of plasma cortisol on counterregulatory responses during subsequent exercise in type 1 diabetes. [2009.09]
Intermittent hormone therapy and its place in the contemporary endocrine treatment of prostate cancer. [2009.09]
Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 (HER2), and epidermal growth factor receptor expression and benefit from lapatinib in a randomized trial of paclitaxel with lapatinib or placebo as first-line treatment in HER2-negative or unknown metastatic breast cancer. [2009.08.20]
Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: a phase 2 randomized study. [2009.08.19]
Regulation of basal, pulsatile, and entropic (patterned) modes of GH secretion in a putatively low-somatostatin milieu in women. [2009.08]
Proteomic profiling of growth hormone-responsive proteins in human peripheral blood leukocytes. [2009.08]
High-dose intramuscular octreotide in patients with acromegaly inadequately controlled on conventional somatostatin analogue therapy: a randomised controlled trial. [2009.08]
Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. [2009.08]
On the alterations in serum concentration of somatotropin and insuline-like growth factor 1 in lactating cows after the treatment with a little studied recombinant bovine somatotropin. [2009.08]
Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. a randomized controlled trial. [2009.07.07]
Short-term administration of a combination of recombinant growth hormone and insulin-like growth factor-I induces anabolism in maintenance hemodialysis. [2009.07]
Hormonal and metabolic responses to slow movement resistance exercise with different durations of concentric and eccentric actions. [2009.07]
Initial body condition score affects hormone and metabolite response to nutritional restriction and repletion in yearling postpubertal beef heifers. [2009.07]
Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp. [2009.07]
Benefits from growth hormone therapy after bariatric surgery. [2009.06]
Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp. [2009.06]
Inhaled growth hormone (GH) compared with subcutaneous GH in children with GH deficiency: pharmacokinetics, pharmacodynamics, and safety. [2009.06]
Treatment for 24 months with recombinant human GH has a beneficial effect on bone mineral density in young adults with childhood-onset GH deficiency. [2009.06]
Effects of exercise training intensity on nocturnal growth hormone secretion in obese adults with the metabolic syndrome. [2009.06]
Testosterone and growth hormone improve body composition and muscle performance in older men. [2009.06]
Free fatty acids inhibit growth hormone/signal transducer and activator of transcription-5 signaling in human muscle: a potential feedback mechanism. [2009.06]
Pharmacodynamic hormonal effects of anamorelin, a novel oral ghrelin mimetic and growth hormone secretagogue in healthy volunteers. [2009.06]
Genetic and epigenetic variability in the gene for IGFBP-3 (IGFBP3): correlation with serum IGFBP-3 levels and growth in short children born small for gestational age. [2009.06]
Blocking AMPA receptor signalling by caroverine infusion does not affect counter-regulation of hypoglycaemia in healthy men. [2009.06]
Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients. [2009.05.01]
Short-term cyproheptadine therapy in underweight children: effects on growth and serum insulin-like growth factor-I. [2009.05]
Effects of amino acids supplement on physiological adaptations to resistance training. [2009.05]
Effect of food on the pharmacokinetics and pharmacodynamics of an oral ghrelin agonist (ARD-07) in healthy subjects. [2009.05]
Dietary protein and calcium interact to influence calcium retention: a controlled feeding study. [2009.05]
Determinants of GH-releasing hormone and GH-releasing peptide synergy in men. [2009.05]
Octreotide LAR vs. surgery in newly diagnosed patients with acromegaly: a randomized, open-label, multicentre study. [2009.05]
Differences in gene expression of granulosa cells from women undergoing controlled ovarian hyperstimulation with either recombinant follicle-stimulating hormone or highly purified human menopausal gonadotropin. [2009.05]
Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone. [2009.05]
An evaluation of the neuroendocrine response to sleep in pediatric burn patients. [2009.05]
Follicular and endocrine response to anastrozole versus clomiphene citrate administered in follicular phase to normoovulatory women: a randomized comparison. [2009.05]
Longitudinal one-year study of levels and stoichiometry of neurofilament heavy and light chain concentrations in CSF in patients with multiple system atrophy. [2009.04.15]
Effects of an oral growth hormone secretagogue in older adults. [2009.04]
Randomized controlled trial to investigate the effects of growth hormone treatment on scoliosis in children with Prader-Willi syndrome. [2009.04]
Prospective analysis of serum carotenoids, vitamin A, and tocopherols in adults with short bowel syndrome undergoing intestinal rehabilitation. [2009.04]
Short-term oral oestrogen therapy dissociates the growth hormone/insulin-like growth factor-I axis without altering energy metabolism in premenopausal women. [2009.04]
[Long GnRH agonist vs. GnRH antagonist protocol in randomized controlled trial in unselected patients--hormonal and cycle characteristics--pilot study] [2009.04]
A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer. [2009.04]
Changes in biochemical indices of bone metabolism in post-menopausal women following a dietary intervention with fortified dairy products. [2009.04]
Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial. [2009.04]
GnRH analogue for the prevention of ovarian hyperstimulation syndrome: a pilot study. [2009.04]
Prospective, randomized trial on late steroid withdrawal in pediatric renal transplant recipients under cyclosporine microemulsion and mycophenolate mofetil. [2009.03.27]
Tesamorelin, a human growth hormone releasing factor analogue. [2009.03]
Effects of acute and chronic exercise on disulfide-linked growth hormone variants. [2009.03]
Effects of prolonged fasting and sustained lipolysis on insulin secretion and insulin sensitivity in normal subjects. [2009.03]
Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men. [2009.03]
Pharmacokinetic and pharmacodynamic profile of a new sustained-release GH formulation, LB03002, in children with GH deficiency. [2009.03]
Use of a GH receptor antagonist (GHRA) to explore the relationship between GH and IGF-I in adults with severe GH deficiency (GHD). [2009.03]
Impact of fasting on growth hormone signaling and action in muscle and fat. [2009.03]
Growth hormone treatment prevents loss of lean mass after bariatric surgery in morbidly obese patients: results of a pilot, open, prospective, randomized, controlled study. [2009.03]
A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome. [2009.03]
Hormonal and cardiovascular response to low-intensity exercise with atropine administration. [2009.03]
Follicular development in a 7-day versus 4-day hormone-free interval with an oral contraceptive containing 20 mcg ethinyl estradiol and 1 mg norethindrone acetate. [2009.03]
The influence of liberal alcohol consumption on glucose metabolism in patients with type 1 diabetes: a pilot study. [2009.03]
Short-term aromatase inhibition: effects on glucose metabolism and serum leptin levels in young and elderly men. [2009.03]
No ghrelin response to oral glucose in diabetes mellitus with gastroparesis. [2009.03]
Growth response to an individualized versus fixed dose GH treatment in short children born small for gestational age: the OPTIMA study. [2009.02]
r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans. [2009.02]
Sleep architecture in Sheehan's syndrome before and 6 months after growth hormone replacement therapy. [2009.02]
Short-term effects of two continuous combined oestrogen-progestogen therapies on several cardiovascular risk markers in healthy postmenopausal women: a randomised controlled trial. [2009.02]
Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements. [2009.02]
Randomized controlled trial to investigate the effects of growth hormone treatment on scoliosis in children with Prader-Willi syndrome. [2009.01.21]
Phosphorylated ERalpha, HIF-1alpha, and MAPK signaling as predictors of primary endocrine treatment response and resistance in patients with breast cancer. [2009.01.10]
Influence of modified transdermal hormone replacement therapy on the concentrations of hormones, growth factors, and bone mineral density in women with osteopenia. [2009.01]
Coexpression of alpha6beta4 integrin and guanine nucleotide exchange factor Net1 identifies node-positive breast cancer patients at high risk for distant metastasis. [2009.01]
Effect of aromatizable and unaromatizable androgen replacement in hypogonadal men on GH responsiveness. [2009.01]
Long-term follow-up of GH-treated girls with Turner syndrome: metabolic consequences. [2009]
Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. [2008.12]
Predictors of calcium retention in adolescent boys. [2008.12]
Increases in bone mineral density in response to oral dehydroepiandrosterone replacement in older adults appear to be mediated by serum estrogens. [2008.12]
Short-term glucocorticoid intake combined with intense training on performance and hormonal responses. [2008.12]
Beta-alanine and the hormonal response to exercise. [2008.12]
Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial. [2008.11.18]
Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. [2008.11.04]
Growth hormone treatment for growth failure in pediatric patients with Crohn's disease. [2008.11]
Improved growth velocity during thyroid hormone therapy in children with Fanconi anemia and borderline thyroid function. [2008.11]
OPPORTUNITY: a randomized clinical trial of growth hormone on outcome in hemodialysis patients. [2008.11]
Dose-dependent effect of growth hormone on final height in children with short stature without growth hormone deficiency. [2008.11]
Estrogen elevates the peak overnight production rate of acylated ghrelin. [2008.11]
Dehydroepiandrosterone replacement therapy in hypoadrenal women: protein anabolism and skeletal muscle function. [2008.11]
Effects of the route of estrogen administration on insulinlike growth factor-I, IGF binding protein-3, and insulin resistance in healthy postmenopausal women: results from a randomized, controlled study. [2008.11]
Combination of bevacizumab and docetaxel in docetaxel-pretreated hormone-refractory prostate cancer: a phase 2 study. [2008.11]
Intravenous calcitriol therapy in an early stage prevents parathyroid gland growth. [2008.11]
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