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Humatrope (Somatropin) - Published Studies

 


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Humatrope Related Published Studies

Well-designed clinical trials related to Humatrope (Somatropin)

Exercise capacity and hormonal response in adults with childhood onset growth hormone deficiency during long-term somatropin treatment. [1998.10]

Outcome of a four-year randomized study of daily versus three times weekly somatropin treatment in prepubertal naive growth hormone-deficient children. Genentech Study Group. [1996.05]

Well-designed clinical trials possibly related to Humatrope (Somatropin)

Growth hormone treatment for growth failure in pediatric patients with Crohn's disease. [2008.11]

Improved growth velocity during thyroid hormone therapy in children with Fanconi anemia and borderline thyroid function. [2008.11]

A randomized controlled crossover trial of the effect of ginseng consumption on the immune response to moderate exercise in healthy sedentary men. [2008.10]

Immune, endocrine, and behavioral precursors to breast cancer recurrence: a case-control analysis. [2008.10]

Effects of the route of estrogen administration on insulinlike growth factor-I, IGF binding protein-3, and insulin resistance in healthy postmenopausal women: results from a randomized, controlled study. [2008.09.17]

Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation. [2008.09.12]

Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men. [2008.09]

Dose-Dependent Effect of Growth Hormone on Final Height in Children with Short Stature without Growth Hormone deficiency. [2008.08.26]

Low-dose physiological growth hormone in patients with HIV and abdominal fat accumulation: a randomized controlled trial. [2008.08.06]

The Effects of Growth Hormone and/or Testosterone on Whole Body Protein Kinetics and Skeletal Muscle Gene Expression in Healthy Elderly Men: A Randomized Controlled Trial. [2008.08]

Induction of tolerance of dopaminergic responses in man. [2008.08]

Serum ghrelin levels in inflammatory bowel disease with relation to disease activity and nutritional status. [2008.08]

Nocturnal nutritional supplementation improves total body protein status of patients with liver cirrhosis: a randomized 12-month trial. [2008.08]

Recombinant human growth hormone increases albumin and prolongs survival in patients with chronic liver failure: a pilot open, randomized, and controlled clinical trial. [2008.07]

Somatotropic responses to soy protein alone and as part of a meal. [2008.07]

The exon 3-deleted/full-length growth hormone receptor polymorphism does not influence the effect of puberty or growth hormone therapy on glucose homeostasis in short non-growth hormone-deficient small-for-gestational-age children: results from a two-year controlled prospective study. [2008.07]

Treatment of altered body composition in HIV-associated lipodystrophy: comparison of rosiglitazone, pravastatin, and recombinant human growth hormone. [2008.07]

Effects of recombinant bovine somatotropin (rbST) and season on plasma and milk insulin-like growth factors I (IGF-I) and II (IGF-II) in lactating dairy cows. [2008.07]

Pregnancy success of lactating Holstein cows after a single administration of a sustained-release formulation of recombinant bovine somatotropin. [2008.06.26]

Growth Hormone Treatment for Growth Failure in Pediatric Patients with Crohn's Disease. [2008.06.25]

A Randomised Study of Two Doses of Biosynthetic Human Growth Hormone on Final Height of Pubertal Children with Growth Hormone Deficiency. [2008.06.12]

Frequent intravenous pulses of growth hormone together with glutamine supplementation in prolonged critical illness after multiple trauma: effects on nitrogen balance, insulin resistance, and substrate oxidation. [2008.06]

Effects of raloxifene and hormone replacement therapy on serum Th2 and Th3 type cytokine concentrations in healthy postmenopausal women: a randomised controlled trial. [2008.06]

Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin. [2008.05.15]

The Effects of Growth Hormone and/or Testosterone on Whole Body Protein Kinetics and Skeletal Muscle Gene Expression in Healthy Elderly Men: A Randomized Controlled Trial. [2008.05.13]

Lapatinib versus hormone therapy in patients with advanced renal cell carcinoma: a randomized phase III clinical trial. [2008.05.10]

24-hour serum levels of growth hormone, prolactin, and cortisol in pre- and postmenopausal women: the effect of combined estrogen and progestin treatment. [2008.05]

Effect of recombinant human TNF-binding protein-1 and GnRH antagonist on mRNA expression of inflammatory cytokines and adhesion and growth factors in endometrium and endometriosis tissues in baboons. [2008.05]

HER2 status in hormone receptor positive premenopausal primary breast cancer adds prognostic, but not tamoxifen treatment predictive, information. [2008.05]

Different responses in postprandial plasma ghrelin and GH levels induced by concentrate or timothy hay feeding in wethers. [2008.05]

Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trial. [2008.05]

The exon 3-deleted/full-length growth hormone receptor polymorphism does not influence the effect of puberty or growth hormone therapy on glucose homeostasis in short non-growth hormone-deficient small-for-gestational-age children: results from a two-year controlled prospective study. [2008.04.29]

Weekly paclitaxel in the adjuvant treatment of breast cancer. [2008.04.17]

Regulation of vascular endothelial growth factor-A and its soluble receptor sFlt-1 by luteinizing hormone in vivo: implication for ovarian follicle angiogenesis. [2008.04]

Effect of growth hormone therapy on nitric oxide formation in cystic fibrosis patients. [2008.04]

An evidence-based approach to hormonal therapies for premenopausal women with fibroids. [2008.04]

Effects of acute prednisolone administration on exercise endurance and metabolism. [2008.04]

Changes in insulin sensitivity and glucose metabolism during therapy with recombinant human growth hormone in short children born small for gestational age show a negative correlation with baseline measurements. [2008.04]

Growth hormone co-treatment within a GnRH agonist long protocol in patients with poor ovarian response: a prospective, randomized, clinical trial. [2008.04]

Randomized controlled growth hormone trial: Effects on anthropometry, body composition, and body proportions in a large group of children with Prader-Willi syndrome. [2008.03.18]

24-h Serum Levels of Growth Hormone, Prolactin and Cortisol in Pre- and Postmenopausal Women. The effect of combined estrogen and progestin treatment. [2008.03.04]

Endocrine and ovarian response after a 2-day controlled suckling and eCG treatment in lactating rabbit does. [2008.03.03]

Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination trial. [2008.03.01]

Growth hormone treatment and fat redistribution in children born small for gestational age. [2008.03]

Anastrozole Increases Predicted Adult Height of Short Adolescent Males Treated with Growth Hormone: A Randomized, Placebo-Controlled, Multicenter Trial for One to Three Years. [2008.03]

The growth hormone response to repeated bouts of sprint exercise with and without suppression of lipolysis in men. [2008.03]

Neuroimmunomodulation in medical oncology: application of psychoneuroimmunology with subcutaneous low-dose IL-2 and the pineal hormone melatonin in patients with untreatable metastatic solid tumors. [2008.03]

Prevention of disuse muscular weakness by restriction of blood flow. [2008.03]

Growth hormone enhances thymic function in HIV-1-infected adults. [2008.03]

A six-month randomized controlled trial of exercise and pyridostigmine in the treatment of fibromyalgia. [2008.02]

Frequent intravenous pulses of growth hormone together with alanylglutamine supplementation in prolonged critical illness after multiple trauma: Effects on glucose control, plasma IGF-I and glutamine. [2008.02]

Estro-progestin supplementation enhances the growth hormone secretory responsiveness to ghrelin infusion in postmenopausal women. [2008.02]

Ghrelin agonist (TZP-101): safety, pharmacokinetics and pharmacodynamic evaluation in healthy volunteers: a phase I, first-in-human study. [2008.02]

Effects of oral ingestion of amino acids and proteins on the somatotropic axis. [2008.02]

Relationship between GH-induced metabolic changes and changes in body composition: a dose and time course study in GH-deficient adults. [2008.02]

Letrozole versus letrozole plus Lapatinib (GW572016) in hormone-sensitive, HER2-negative operable breast cancer: a double-blind, randomized, phase II study with biomarker evaluation (EGF109077-LAP107692/LETLOB). [2008.02]

An examination of the role of feeding regimens in regulating metabolism during the broiler breeder grower period. 2. Plasma hormones and metabolites. [2008.02]

Growth hormone replacement therapy in adults with growth hormone deficiency improves maximal oxygen consumption independently of dosing regimen or physical activity. [2008.01]

Growth hormone isoform responses to GABA ingestion at rest and after exercise. [2008.01]

Effects of acute prednisolone intake on substrate utilization during submaximal exercise. [2008.01]

Human blood neutrophil responses to prolonged exercise with and without a thermal clamp. [2008.01]

Exposure to human chorionic gonadotropin during in vitro maturation does not improve the maturation rate and developmental potential of immature oocytes from patients with polycystic ovary syndrome. [2008.01]

The use of gonadotropin-releasing hormone (GnRH) agonist to induce oocyte maturation after cotreatment with GnRH antagonist in high-risk patients undergoing in vitro fertilization prevents the risk of ovarian hyperstimulation syndrome: a prospective randomized controlled study. [2008.01]

Evaluation of the pituitary function with insulin tolerance (hypoglycaemia) testing: are there any differences using insulin lispro compared to regular insulin? [2008]

A randomised study of the effect of two doses of biosynthetic human growth hormone on final height of children with familial short stature. [2008]

A randomised study of two doses of biosynthetic human growth hormone on final height of pubertal children with growth hormone deficiency. [2008]

Prednisone plus gefitinib versus prednisone plus placebo in the treatment of hormone-refractory prostate cancer: a randomized phase II trial. [2008]

Anastrozole Increases Predicted Adult Height of short adolescent males treated with growth hormone: A Randomized, Placebo-Controlled, Multicenter Trial for One to Three Years. [2007.12.28]

Recombinant human growth hormone increases albumin and prolongs survival in patients with chronic liver failure: A pilot open, randomized, and controlled clinical trial. [2007.12.27]

Metabolic effects of a growth hormone-releasing factor in patients with HIV. [2007.12.06]

Overture for growth hormone: requiem for interleukin-6? [2007.12]

Effects of an amino acid/creatine energy supplement on the acute hormonal response to resistance exercise. [2007.12]

Effect of protein-rich feeding on recovery after intense exercise. [2007.12]

Early elective insulin therapy can reduce hyperglycemia and increase insulin-like growth factor-I levels in very low birth weight infants. [2007.12]

Growth hormone as concomitant treatment in severe fibromyalgia associated with low IGF-1 serum levels. A pilot study. [2007.11.30]

Lipolysis and fatty acid metabolism in men and women during the postexercise recovery period. [2007.11.01]

Pregnancy rates in lactating dairy cattle following supplementation of progesterone after artificial insemination. [2007.11]

Modulation of the acoustic startle response by the level of arousal: comparison of clonidine and modafinil in healthy volunteers. [2007.11]

Effects of a multi-nutrient supplement on exercise performance and hormonal responses to resistance exercise. [2007.11]

Effect of growth hormone on body composition and visceral adiposity in middle-aged men with visceral obesity. [2007.11]

Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride. [2007.11]

Triggering final oocyte maturation using different doses of human chorionic gonadotropin: a randomized pilot study in patients with polycystic ovary syndrome treated with gonadotropin-releasing hormone antagonists and recombinant follicle-stimulating hormone. [2007.11]

Reduction in proliferation with six months of letrozole in women on hormone replacement therapy. [2007.11]

The effect of red wine on plasma leptin levels and vasoactive factors from adipose tissue: a randomized crossover trial. [2007.11]

Pharmacokinetics of recombinant human growth hormone administered by cool.click 2, a new needle-free device, compared with subcutaneous administration using a conventional syringe and needle. [2007.10.08]

Efficacy of hCG and GnRH for inducing ovulation in the jenny. [2007.10.01]

Validation of the growth hormone (GH)-dependent marker method of detecting GH abuse in sport through the use of independent data sets. [2007.10]

Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women. [2007.10]

Long-term effects of growth hormone (GH) treatment on body composition and bone mineral density in short children born small-for-gestational-age: six-year follow-up of a randomized controlled GH trial. [2007.10]

Behavioural effects of rapid intravenous administration of meta-chlorophenylpiperazine (m-CPP) in patients with generalized social anxiety disorder, panic disorder and healthy controls. [2007.10]

Bacterial endotoxin induces biphasic changes in plasma ghrelin in healthy humans. [2007.10]

Longitudinal measures of circulating leptin and ghrelin concentrations are associated with the growth of young Peruvian children but are not affected by zinc supplementation. [2007.10]

Milk consumption and the prepubertal somatotropic axis. [2007.09.27]

Randomized dose-ranging trial of tamoxifen at low doses in hormone replacement therapy users. [2007.09.20]

A phase II placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer. [2007.09.01]

Lack of an acute effect of ghrelin on markers of bone turnover in healthy controls and post-gastrectomy subjects. [2007.09]

Estimation of the size and shape of GH secretory bursts in healthy women using a physiological estradiol clamp and variable-waveform deconvolution model. [2007.09]

Dopamine versus dobutamine in very low birthweight infants: endocrine effects. [2007.09]

Growth hormone treatment of early growth failure in toddlers with Turner syndrome: a randomized, controlled, multicenter trial. [2007.09]

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