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HMS (Medrysone Ophthalmic) - Description and Clinical Pharmacology

 
 



HMS®
(medrysone ophthalmic suspension) 1%

Sterile

DESCRIPTION

HMS® (medrysone ophthalmic suspension) 1% is a topical anti-inflammatory agent for ophthalmic use.

Chemical Name:

11β-hydroxy-6α-methylpregn-4-ene-3,20-dione

Structural Formula:

Contains: Active: Medrysone 1%. Preservative: benzalkonium chloride 0.004%.

Inactives: edetate disodium; hypromellose; polyvinyl alcohol 1.4%; potassium chloride; purified water; sodium chloride; sodium phosphate, dibasic; sodium phosphate, monobasic; and sodium hydroxide to adjust the pH (6.2 - 7.5).

CLINICAL PHARMACOLOGY

HMS® (medrysone ophthalmic suspension) is a synthetic corticosteroid with topical anti-inflammatory activity. Glucocorticoids inhibit the edema, fibrin deposition, capillary dilation and phagocytic migration of the acute inflammatory response as well as capillary proliferation, deposition of collagen, and scar formation. HMS® (medrysone ophthalmic suspension) has less anti-inflammatory potency than 0.1% dexamethasone.

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