DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Hexalen (Altretamine) - Summary

 

-- advertisement --

WARNINGS

  1. HEXALEN® capsules should only be given under the supervision of a physician experienced in the use of antineoplastic agents.
  2. Peripheral blood counts should be monitored at least monthly, prior to the initiation of each course of HEXALEN® capsules, and as clinically indicated (see Adverse Reactions).
  3. Because of the possibility of HEXALEN® capsules-related neurotoxicity, neurologic examination should be performed regularly during HEXALEN® capsules administration (see Adverse Reactions).
 

HEXALEN SUMMARY

HEXALEN®
(ALTRETAMINE) CAPSULES 50 mg

HEXALEN (altretamine), is a synthetic cytotoxic antineoplastic s-triazine derivative. HEXALEN capsules contain 50 mg of altretamine for oral administration. Inert ingredients include lactose, anhydrous and calcium stearate.

HEXALEN is indicated for use as a single agent in the palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent-based combination.

HEXALEN NEWS HIGHLIGHTS

Media Articles Related to Hexalen (Altretamine)

FDA Warns LabCorp About Illegal Sales Of Ovarian Cancer Test
Source: Medical Devices / Diagnostics News From Medical News Today [2008.10.09]

FDA Says Ovarian Cancer Test is Marketed Illegally
Source: MedPageToday.com - medical news plus CME for physicians [2008.10.09]

Researchers ID Ovarian Cancer Biomarker
Source: MedicineNet Ovarian Cancer Specialty [2008.09.24]

Drug Combo Fights Recurrent Ovarian Cancer Cell Growth
Source: MedicineNet Cervical Cancer Specialty [2008.09.19]

Ovarian Cancer
Source: MedicineNet Cancer Causes Specialty [2008.07.10]

more>>

Published Studies Related to Hexalen (Altretamine)

The bioavailability of three altretamine formulations. [1989.12.15]

Long-term follow-up of a phase II trial of oral altretamine for consolidation of clinical complete remission in women with stage III epithelial ovarian cancer in the Southwest Oncology Group. [2004.03]

Oral altretamine used as salvage therapy in recurrent ovarian cancer. [2004.01]

Altretamine (hexamethylmelamine) in the treatment of platinum-resistant ovarian cancer: a phase II study. [2003.02]

A phase I study of paclitaxel and altretamine as second-line therapy to cisplatin regimens for ovarian cancer. [2001.08]

more>>

Clinical Trials Related to Hexalen (Altretamine)

Altretamine and Etoposide in Treating Patients With HIV-Related Cancer [Completed]

more>>

Page last updated: 2008-10-09

-- advertisement -- The American Red Cross

We comply with
HONcode standard.
Verify here.
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2008