DRUG INTERACTIONS
Since adefovir is eliminated by the kidney, co-administration of HEPSERA with drugs that reduce renal function or compete for active tubular secretion may increase serum concentrations of either adefovir and/or these co-administered drugs [see Clinical Pharmacology].
Patients should be monitored closely for adverse events when HEPSERA is co-administered with drugs that are excreted renally or with other drugs known to affect renal function [see Warnings and Precautions
].
HEPSERA should not be administered in combination with VIREAD [see Warnings and Precautions
].
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