CLINICAL PHARMACOLOGY
HalfLytely and Bisacodyl Tablets Bowel Prep Kit induces a diarrhea which cleanses the bowel. Bisacodyl is a contact stimulant laxative. After being hydrolyzed by intestinal brush border enzymes and colonic bacteria, its active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2 methane (BHPM) acts directly on the colonic mucosa to produce peristalsis throughout the large intestine.
The osmotic activity of polyethylene glycol 3350 and electrolytes result in virtually no net absorption or excretion of ions or water.
|