HALDOL® Decanoate 50 (haloperidol)
HALDOL® Decanoate 100 (haloperidol)
For IM Injection Only
Haloperidol decanoate is the decanoate ester of the butyrophenone, HALDOL (haloperidol). It has a markedly extended duration of effect.
HALDOL Decanoate 50 and HALDOL Decanoate 100 are indicated for the treatment of schizophrenic patients who require prolonged parenteral antipsychotic therapy.
Media Articles Related to Haldol (Haloperidol)
Antipsychotic Use Increases Mortality in Parkinson's
Source: Medscape NeurologyHeadlines [2015.06.23]
Drugs to treat Parkinson's psychosis conferred excess mortality risk in the first 6 months, a study shows. Atypicals were safer than haloperidol but still conferred 2- to 3-fold excess mortality.
Medscape Medical News
Published Studies Related to Haldol (Haloperidol)
Quetiapine versus haloperidol in the treatment of delirium: a double-blind,
randomized, controlled trial. 
delirious behavior... CONCLUSION: Low-dose quetiapine and haloperidol may be equally effective and safe
Faster onset of antimanic action with haloperidol compared to second-generation
antipsychotics. A meta-analysis of randomized clinical trials in acute mania. 
CONCLUSIONS: haloperidol shows a faster onset of antimanic action than
Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide
in schizophrenia. 
Oxidative stress may be involved in the pathophysiology of schizophrenia...
Efficacy and safety of olanzapine in the treatment of Japanese patients with
bipolar I disorder in a current manic or mixed episode: a randomized,
double-blind, placebo- and haloperidol-controlled study. 
manic/mixed episode... CONCLUSIONS: This was the first study to evaluate an atypical antipsychotic in
Haloperidol prophylaxis decreases delirium incidence in elderly patients after noncardiac surgery: A randomized controlled trial. [2011.11.03]
OBJECTIVES:: To evaluate the efficacy and safety of short-term low-dose intravenous haloperidol for delirium prevention in critically ill elderly patients after noncardiac surgery... CONCLUSIONS:: For elderly patients admitted to intensive care unit after noncardiac surgery, short-term prophylactic administration of low-dose intravenous haloperidol significantly decreased the incidence of postoperative delirium. The therapy was well-tolerated.
Clinical Trials Related to Haldol (Haloperidol)
Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy Volunteers [Not yet recruiting]
RATIONALE: Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into
the skin, may be an effective treatment for nausea and vomiting. PURPOSE: This clinical trial
studies lorazepam, diphenhydramine hydrochloride, and haloperidol gel in healthy volunteers.
Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Patients With Nausea [Recruiting]
This randomized clinical trial studies lorazepam, diphenhydramine hydrochloride, and
haloperidol gel in patients with nausea. Lorazepam, diphenhydramine hydrochloride, and
haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and
Methylphenidate, Rivastigmine or Haloperidol in Hypoactive Delirium in Intensive Care Patients [Terminated]
The purpose of this pilot-trial is the feasibility of a large randomized, placebo controlled,
doubleblind clinical trial to investigate the use of methylphenidate, rivastigmine or
haloperidol in hypoactive ICU-delirium. In addition we will compare duration of delirium,
severity of delirium, length of ICU/hospital stay and side effects between the different
Haloperidol vs Olanzapine for the Management of ICU Delirium [Recruiting]
The purpose of this randomized clinical trial is to determine whether haloperidol is
superior to olanzapine for the treatment of ICU acquired delirium. The hypothesis is that
haloperidol is in fact superior to olanzapine in treating ICU acquired delirium and
sustaining delirium free time.
IM Olanzapine Versus IM Haloperidol Plus Lorazepam for Acute Agitation in Schizophrenia [Recruiting]
The aim of this study was to compare the efficacy and safety of intramuscular 10 mg
olanzapine versus intramuscular 5 mg haloperidol plus lorazepam 2 mg in the treatment of
acute agitated schizophrenic patients of Taiwanese populations.
Reports of Suspected Haldol (Haloperidol) Side Effects
Self Injurious Behaviour (38),
Multiple Drug Overdose Intentional (34),
Psychotic Disorder (27),
Suicide Attempt (27),
Electrocardiogram QT Prolonged (21),
Extrapyramidal Disorder (21),
Death (20), more >>
PATIENT REVIEWS / RATINGS / COMMENTS
Based on a total of 1 ratings/reviews, Haldol has an overall score of 10. The effectiveness score is 10 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst.
Haldol review by medical professional caring for 23 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Highly Effective|
|Side effects:|| || No Side Effects|
|Condition / reason:|| || psychotic out nof control patient|
|Dosage & duration:|| || 5mg taken given on a prn basis for the period of given on a prn basis|
|Other conditions:|| || borderline personality disorder|
|Other drugs taken:|| || ativan,|
|Benefits:|| || Was able to gain control after receiving the injection form of the medication.Was helpful in decreasing aggitation,psychosis,delusions.At the end of the required time in seclusion and after giving medication time to take effect patient was able to return to facility population without any further problems.Was able to maintain in a calm manner,much less aggitated and was able to meet to staff to discuss delional ideas.|
|Side effects:|| || Drownsy but no untoward effects.Patient was able to be put on routine dose of this medication after effectivness of medication was evaluated to help prevent further problems.When routine dosage was begun patient was given routine medications for any side effects.|
|Comments:|| || Patient became aggiatated,delusional and psychotic and needed to be medicated for safty of patient and others.Required seclusion for decrease stimuli for mediation to take effect.Patient was medicated and given the quiet of seclusion and was monitored for saftey.At the end of seclusion time was released and placed back into the facility mileu.|
Page last updated: 2015-06-23