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Haldol (Haloperidol) - Summary



HALDOL® Decanoate 50 (haloperidol)
HALDOL® Decanoate 100 (haloperidol)
For IM Injection Only

Haloperidol decanoate is the decanoate ester of the butyrophenone, HALDOL (haloperidol). It has a markedly extended duration of effect.

HALDOL Decanoate 50 and HALDOL Decanoate 100 are indicated for the treatment of schizophrenic patients who require prolonged parenteral antipsychotic therapy.

See all Haldol indications & dosage >>


Published Studies Related to Haldol (Haloperidol)

Quetiapine versus haloperidol in the treatment of delirium: a double-blind, randomized, controlled trial. [2013]
delirious behavior... CONCLUSION: Low-dose quetiapine and haloperidol may be equally effective and safe

Faster onset of antimanic action with haloperidol compared to second-generation antipsychotics. A meta-analysis of randomized clinical trials in acute mania. [2013]
CONCLUSIONS: haloperidol shows a faster onset of antimanic action than

Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide in schizophrenia. [2012]
Oxidative stress may be involved in the pathophysiology of schizophrenia...

Efficacy and safety of olanzapine in the treatment of Japanese patients with bipolar I disorder in a current manic or mixed episode: a randomized, double-blind, placebo- and haloperidol-controlled study. [2012]
manic/mixed episode... CONCLUSIONS: This was the first study to evaluate an atypical antipsychotic in

Haloperidol prophylaxis decreases delirium incidence in elderly patients after noncardiac surgery: A randomized controlled trial. [2011.11.03]
OBJECTIVES:: To evaluate the efficacy and safety of short-term low-dose intravenous haloperidol for delirium prevention in critically ill elderly patients after noncardiac surgery... CONCLUSIONS:: For elderly patients admitted to intensive care unit after noncardiac surgery, short-term prophylactic administration of low-dose intravenous haloperidol significantly decreased the incidence of postoperative delirium. The therapy was well-tolerated.

more studies >>

Clinical Trials Related to Haldol (Haloperidol)

Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy Volunteers [Not yet recruiting]
RATIONALE: Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting. PURPOSE: This clinical trial studies lorazepam, diphenhydramine hydrochloride, and haloperidol gel in healthy volunteers.

Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Patients With Nausea [Recruiting]
This randomized clinical trial studies lorazepam, diphenhydramine hydrochloride, and haloperidol gel in patients with nausea. Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting.

Methylphenidate, Rivastigmine or Haloperidol in Hypoactive Delirium in Intensive Care Patients [Terminated]
The purpose of this pilot-trial is the feasibility of a large randomized, placebo controlled, doubleblind clinical trial to investigate the use of methylphenidate, rivastigmine or haloperidol in hypoactive ICU-delirium. In addition we will compare duration of delirium, severity of delirium, length of ICU/hospital stay and side effects between the different interventions.

Haloperidol vs Olanzapine for the Management of ICU Delirium [Recruiting]
The purpose of this randomized clinical trial is to determine whether haloperidol is superior to olanzapine for the treatment of ICU acquired delirium. The hypothesis is that haloperidol is in fact superior to olanzapine in treating ICU acquired delirium and sustaining delirium free time.

IM Olanzapine Versus IM Haloperidol Plus Lorazepam for Acute Agitation in Schizophrenia [Recruiting]
The aim of this study was to compare the efficacy and safety of intramuscular 10 mg olanzapine versus intramuscular 5 mg haloperidol plus lorazepam 2 mg in the treatment of acute agitated schizophrenic patients of Taiwanese populations.

more trials >>

Reports of Suspected Haldol (Haloperidol) Side Effects

Somnolence (40)Self Injurious Behaviour (38)Fall (34)Multiple Drug Overdose Intentional (34)Sopor (29)Psychotic Disorder (27)Suicide Attempt (27)Electrocardiogram QT Prolonged (21)Extrapyramidal Disorder (21)Death (20)more >>


Based on a total of 1 ratings/reviews, Haldol has an overall score of 10. The effectiveness score is 10 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst.

Haldol review by medical professional caring for 23 year old female patient

Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
Treatment Info
Condition / reason:   psychotic out nof control patient
Dosage & duration:   5mg taken given on a prn basis for the period of given on a prn basis
Other conditions:   borderline personality disorder
Other drugs taken:   ativan,
Reported Results
Benefits:   Was able to gain control after receiving the injection form of the medication.Was helpful in decreasing aggitation,psychosis,delusions.At the end of the required time in seclusion and after giving medication time to take effect patient was able to return to facility population without any further problems.Was able to maintain in a calm manner,much less aggitated and was able to meet to staff to discuss delional ideas.
Side effects:   Drownsy but no untoward effects.Patient was able to be put on routine dose of this medication after effectivness of medication was evaluated to help prevent further problems.When routine dosage was begun patient was given routine medications for any side effects.
Comments:   Patient became aggiatated,delusional and psychotic and needed to be medicated for safty of patient and others.Required seclusion for decrease stimuli for mediation to take effect.Patient was medicated and given the quiet of seclusion and was monitored for saftey.At the end of seclusion time was released and placed back into the facility mileu.

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Page last updated: 2014-11-30

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