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GUANFACINE TABLETS, USP
1 mg and 2 mg
Rx only
DESCRIPTION
Guanfacine hydrochloride is a centrally acting antihypertensive with α2-adrenoceptor agonist properties in tablet form for oral administration.
The structural formula is:
The chemical name of guanfacine hydrochloride is N-amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride and its molecular weight is 282.56.
Guanfacine hydrochloride is a white to off-white powder; sparingly soluble in water and alcohol and slightly soluble in acetone.
Each tablet, for oral administration, contains guanfacine hydrochloride equivalent to 1 or 2 mg of guanfacine and the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose and sodium lauryl sulfate. In addition, the 2 mg tablets contain the following ingredient: FD&C Blue #1 Aluminum Lake.
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