Guaifenesin-DM NR Liquid is a clear yellow liquid with a raspberry flavor.
Each 5 mL (1 teaspoonful) contains:
Guaifenesin 100 mg.
Dextromethorphan Hydrobromide 10 mg.
GUAIFENESIN-DM NR LIQUID (Guaifenesin/Dextromethorphan) is indicated for the following:
Temporarily relieves cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants. Calms the cough control center and relieves coughing. Helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus, drain bronchial tubes, and make coughs more productive.
Media Articles Related to Guaifenesin-DM NR Liquid (Guaifenesin / Dextromethorphan)
California Infants Hit Hard by Whooping Cough Epidemic: Report
Source: MedicineNet Pertussis Specialty [2014.12.05]
Title: California Infants Hit Hard by Whooping Cough Epidemic: Report
Category: Health News
Created: 12/4/2014 12:00:00 AM
Last Editorial Review: 12/5/2014 12:00:00 AM
When to Call the Doctor: Fever, Nausea, Diarrhea, Colds, and Coughs
Source: MedicineNet Bruises Specialty [2014.12.01]
Title: When to Call the Doctor: Fever, Nausea, Diarrhea, Colds, and Coughs
Category: Doctor's Views
Created: 12/20/2010 12:00:00 AM
Last Editorial Review: 12/1/2014 12:00:00 AM
Whooping Cough Vaccine Seems Safe in Pregnancy, Study Finds
Source: MedicineNet Pertussis Specialty [2014.11.12]
Title: Whooping Cough Vaccine Seems Safe in Pregnancy, Study Finds
Category: Health News
Created: 11/11/2014 12:00:00 AM
Last Editorial Review: 11/12/2014 12:00:00 AM
Placebos are 'more effective than no treatment' for children's coughs
Source: Complementary Medicine / Alternative Medicine News From Medical News Today [2014.10.28]
Both agave nectar and a placebo were more effective at reducing cough symptoms among children under 2 years than watchful waiting, according to a new study.
Placebo Treatment May Quiet Kids' Cough
Source: MedicineNet Botulism Specialty [2014.10.28]
Title: Placebo Treatment May Quiet Kids' Cough
Category: Health News
Created: 10/27/2014 12:00:00 AM
Last Editorial Review: 10/28/2014 12:00:00 AM
Published Studies Related to Guaifenesin-DM NR Liquid (Guaifenesin / Dextromethorphan)
Simultaneous determination of dextromethorphan, dextrorphan, and guaifenesin in human plasma using semi-automated liquid/liquid extraction and gradient liquid chromatography tandem mass spectrometry. [2007.01.17]
A method for the simultaneous determination of dextromethorphan (DEX), dextrorphan (DET), and guaifenesin (GG) in human plasma was developed, validated, and applied to determine plasma concentrations of these compounds in samples from six clinical pharmacokinetic (PK) studies... Pharmacokinetic data are also provided to illustrate improvements in systemic drug and metabolite concentration-time profiles that were achieved by formulation optimization.
Clinical Trials Related to Guaifenesin-DM NR Liquid (Guaifenesin / Dextromethorphan)
Placebo Controlled Trial of Dextromethorphan in Rett Syndrome [Recruiting]
Dr. Sakkubai Naidu, Principal Investigator, is initiating a double blinded placebo
controlled clinical drug trial using dextromethorphan (DM) in Rett Syndrome (RTT), at the
Pediatric Clinical Research Unit (PCRU) of the Johns Hopkins Hospital/Kennedy Krieger
Funding Source- FDA OOPD and the Johns Hopkins Institute for Clinical and Translational
It has been shown that receptors for a certain brain chemical called glutamate, in
particular the NMDA type, are increased in the brain of young RTT patients (<10 years of
age). This chemical and its receptors, when in excess, cause harmful over-stimulation of
nerve cells in the brain, contributing in part to the seizures, behavioral problems, and
learning disabilities in RTT.
The investigators propose to initiate a specific treatment using DM to counter/block the
effects of this brain chemical and its excessive receptors to improve the ill effects of
increased glutamate/NMDA receptors, because of DM's identified ability to block NMDA
receptors. DM is available for human consumption. Infants and children with respiratory
infections and cough, as well as non-ketotic hyperglycinemia, are treated with DM, which has
been well tolerated.
Combined Therapy of Methadone and Dextromethrophan [Recruiting]
The purpose of this study is to determine the pharmacological effects and outcomes of DM
therapy with this add-on study.
And to determine the immunological changes between the baseline and the end point of the
Page last updated: 2014-12-05