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Genotropin (Somatropin) - Published Studies


Genotropin Related Published Studies

Well-designed clinical trials related to Genotropin (Somatropin)

Cost-effectiveness of somatropin for the treatment of short children born small for gestational age. [2010.06]

Bioequivalence between novel ready-to-use liquid formulations of the recombinant human GH Omnitrope and the original lyophilized formulations for reconstitution of Omnitrope and Genotropin. [2010.06]

Relative bioavailability of two drug products of somatropin obtained from either the milk of transgenic cows or bacterial culture. [2010]

Cost-effectiveness of somatropin for the treatment of short children born small for gestational age. [2010]

Bioequivalence between novel ready-to-use liquid formulations of the recombinant human GH Omnitrope and the original lyophilized formulations for reconstitution of Omnitrope and Genotropin. [2010]

Effect of the inhaled corticosteroid mometasone on small airway patency in patients with asthma. [2009.05]

Exercise capacity and hormonal response in adults with childhood onset growth hormone deficiency during long-term somatropin treatment. [1998.10]

A low starting dose of genotropin in growth hormone-deficient adults. [1997.01]

Outcome of a four-year randomized study of daily versus three times weekly somatropin treatment in prepubertal naive growth hormone-deficient children. Genentech Study Group. [1996.05]

Well-designed clinical trials possibly related to Genotropin (Somatropin)

Double-blind, placebo-controlled, multicenter, randomized, phase IIb neoadjuvant study of letrozole-lapatinib in postmenopausal hormone receptor-positive, human epidermal growth factor receptor 2-negative, operable breast cancer. [2014]

Endocrine therapy with or without inhibition of epidermal growth factor receptor and human epidermal growth factor receptor 2: a randomized, double-blind, placebo-controlled phase III trial of fulvestrant with or without lapatinib for postmenopausal women with hormone receptor-positive advanced breast cancer-CALGB 40302 (Alliance). [2014]

Ganitumab with either exemestane or fulvestrant for postmenopausal women with advanced, hormone-receptor-positive breast cancer: a randomised, controlled, double-blind, phase 2 trial. [2013]

Association of higher plasma vitamin D binding protein and lower free calcitriol levels with tenofovir disoproxil fumarate use and plasma and intracellular tenofovir pharmacokinetics: cause of a functional vitamin D deficiency? [2013]

Effects of midazolam and nitrous oxide on endocrine and metabolic measurements in children. [2012]

Breast cancer risk during hormone therapy: experimental versus clinical data. [2012]

An effective night slimming topical treatment. [2012]

Hair regrowth with topical triiodothyronine ointment in patients with alopecia areata: a double-blind, randomized pilot clinical trial of efficacy. [2012]

OPPORTUNITY™: a large-scale randomized clinical trial of growth hormone in hemodialysis patients. [2011.12]

Growth hormone to improve short bowel syndrome intestinal autonomy: a pediatric randomized open-label clinical trial. [2011.11]

A multi-center controlled trial of growth hormone treatment in children with cystic fibrosis. [2011.09.08]

Long-acting pegylated human GH in children with GH deficiency: a single-dose, dose-escalation trial investigating safety, tolerability, pharmacokinetics and pharmacodynamics. [2011.09]

Increased serum and bone matrix levels of transforming growth factor {beta}1 in patients with GH deficiency in response to GH treatment. [2011.09]

Effect of a high-protein diet on ghrelin, growth hormone, and insulin-like growth factor-I and binding proteins 1 and 3 in subjects with type 2 diabetes mellitus. [2011.09]

Growth hormone axis treatments for HIV-associated lipodystrophy: a systematic review of placebo-controlled trials. [2011.09]

Effect of intensive insulin therapy on the somatotropic axis of critically ill children. [2011.08]

Cotreatment with pegvisomant and a somatostatin analog (SA) in SA-responsive acromegalic patients. [2011.08]

Fasting, but not exercise, increases adipose triglyceride lipase (ATGL) protein and reduces G(0)/G(1) switch gene 2 (G0S2) protein and mRNA content in human adipose tissue. [2011.08]

Gender, sex-steroid, and secretagogue-selective recovery from growth hormone-induced feedback in older women and men. [2011.08]

Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults. [2011.08]

Selenium, thiobarbituric acid reactive substances, and thyroid hormone activation in broilers supplemented with selenium as selenized yeast or sodium selenite. [2011.08]

Sorbic acid improves growth performance and regulates insulin-like growth factor system gene expression in swine. [2011.08]

Sleep after vaccination boosts immunological memory. [2011.07.01]

In vitro viability and secretory capacity of human luteinized granulosa cells after gonadotropin-releasing hormone agonist trigger of oocyte maturation. [2011.07]

Ghrelin modulates sympathetic nervous system activity and stress response in lean and overweight men. [2011.07]

Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study. [2011.07]

Assessment of immune function after short-term administration of recombinant human growth hormone in healthy young males. [2011.07]

Concentration of progesterone during the development of the ovulatory follicle: II. Ovarian and uterine responses. [2011.07]

The reconstitution of the thymus in immunosuppressed individuals restores CD4-specific cellular and humoral immune responses. [2011.07]

A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results. [2011.06.25]

Effects of tesamorelin on inflammatory markers in HIV patients with excess abdominal fat: relationship with visceral adipose reduction. [2011.06.19]

Six-month preoperative octreotide treatment in unselected, de novo patients with acromegaly: effect on biochemistry, tumour volume, and postoperative cure. [2011.06]

GH receptor blocker administration and muscle-tendon collagen synthesis in humans. [2011.06]

Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp. [2011.06]

Effects of once-weekly sustained-release growth hormone: a double-blind, placebo-controlled study in adult growth hormone deficiency. [2011.06]

Long-term response to GH therapy in short children with a delayed infancy-childhood transition (DICT). [2011.06]

Treatment with growth hormone, somatostatin, and insulin in combination with hypocaloric parenteral nutrition in gastrointestinal cancer patients after surgery. [2011.06]

Effects of a dairy supplement and resistance training on lean mass and insulin-like growth factor in women. [2011.06]

Areal and volumetric bone mineral density and geometry at two levels of protein intake during caloric restriction: a randomized, controlled trial. [2011.06]

The acute effects of a low and high dose of oral L-arginine supplementation in young active males at rest. [2011.06]

Comparison of a 24-day and a 21-day pill regimen for the novel combined oral contraceptive, nomegestrol acetate and 17beta-estradiol (NOMAC/E2): a double-blind, randomized study. [2011.06]

Acute and cumulative effects of focused high-frequency vibrations on the endocrine system and muscle strength. [2011.06]

Health-related quality of life of young adults with Turner syndrome following a long-term randomized controlled trial of recombinant human growth hormone. [2011.05.29]

Insulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose load. [2011.05.03]

A preliminary trial of the effect of recombinant human growth hormone on short-term linear growth and glucose homeostasis in children with Crohn's disease. [2011.05]

Levels of the epidermal growth factor-like peptide amphiregulin in follicular fluid reflect the mode of triggering ovulation: a comparison between gonadotrophin-releasing hormone agonist and urinary human chorionic gonadotrophin. [2011.05]

Timing oocyte collection in GnRH agonists down-regulated IVF and ICSI cycles: a randomized clinical trial. [2011.05]

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women. [2011.05]

Leptin is an effective treatment for hypothalamic amenorrhea. [2011.04.19]

Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: randomised, double blind, placebo controlled trial. [2011.04.14]

Supplementation of equine early spring transitional follicles with luteinizing hormone stimulates follicle growth but does not restore steroidogenic activity. [2011.04.01]

Motesanib, or open-label bevacizumab, in combination with paclitaxel, as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: a phase 2, randomised, double-blind, placebo-controlled study. [2011.04]

Progesterone prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women. [2011.04]

Interaction between testosterone and growth hormone on whole-body protein anabolism occurs in the liver. [2011.04]

Effect of recombinant growth hormone on leptin, adiponectin, resistin, interleukin-6, tumor necrosis factor-alpha and ghrelin levels in growth hormone-deficient children. [2011.04]

Alterations in expression of gluconeogenic genes during heat stress and exogenous bovine somatotropin administration. [2011.04]

Effects of exercise training on maternal hormonal changes in pregnancy. [2011.04]

Effect of thermal stress, restricted feeding and combined stresses (thermal stress and restricted feeding) on growth and plasma reproductive hormone levels of Malpura ewes under semi-arid tropical environment. [2011.04]

Growth hormone plus childhood low-dose estrogen in Turner's syndrome. [2011.03.31]

Durability of the Effects of Testosterone and Growth Hormone Supplementation in Older Community Dwelling Men: The HORMA Trial. [2011.03.04]

Gefitinib or placebo in combination with tamoxifen in patients with hormone receptor-positive metastatic breast cancer: a randomized phase II study. [2011.03.01]

Effect of oral phosphate and alendronate on bone mineral density when given as adjunctive therapy to growth hormone replacement in adult growth hormone deficiency. [2011.03]

A diet high in meat protein and potential renal acid load increases fractional calcium absorption and urinary calcium excretion without affecting markers of bone resorption or formation in postmenopausal women. [2011.03]

Pegylated long-acting human growth hormone possesses a promising once-weekly treatment profile, and multiple dosing is well tolerated in adult patients with growth hormone deficiency. [2011.03]

Effects of growth hormone and nutritional therapy in boys with constitutional growth delay: a randomized controlled trial. [2011.03]

Effects of ghrelin on psychopathology, sleep and secretion of cortisol and growth hormone in patients with major depression. [2011.03]

[Influence of estradiol administration mode on plasma insulin-like growth factor-I (IGF-I) and its binding proteins 1 and 3 concentration in postmenopausal women treated with norethisterone acetate]. [2011.03]

Performance, metabolic, and endocrine responses of periparturient Holstein cows fed 3 sources of fat. [2011.03]

Induced lactation in pubertal heifers: efficacy, response to bovine somatotropin, and profitability. [2011.03]

Effect of the prolactin-release inhibitor quinagolide on lactating dairy cows. [2011.03]

Short-term glucocorticoid intake and metabolic responses during long-lasting exercise. [2011.03]

Effects of short-term treatment with orlistat on growth hormone/insulin-like growth factor-I axis in obese post-menopausal women. [2011.02]

Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise. [2011.02]

Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease. [2011.02]

Effect of oxandrolone on glucose metabolism in growth hormone-treated girls with Turner syndrome. [2011.02]

Hormonal responses to resistance exercise after ingestion of carnosine and anserine. [2011.02]

Influence of acute aerobic exercise on adiponectin oligomer concentrations in middle-aged abdominally obese men. [2011.02]

Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves. [2011.02]

Acute peripheral metabolic effects of intraarterial ghrelin infusion in healthy young men. [2011.02]

FGF-23 as a predictor of renal outcome in diabetic nephropathy. [2011.02]

Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease. [2011.02]

Testosterone threshold levels and lean tissue mass targets needed to enhance skeletal muscle strength and function: the HORMA trial. [2011.01]

Effects of insulin-like growth factor-I administration on in vivo regulation of urea synthesis in normal subjects and patients with cirrhosis. [2011.01]

Interleukin 1 receptor antagonist is associated with changes in body composition during physiological GH substitution in patients with adult-onset growth hormone deficiency. [2011.01]

Moderate doses of hGH (0.64 mg/d) improve lipids but not cardiovascular function in GH-deficient adults with normal baseline cardiac function. [2011.01]

Comparative growth performance of pigs immunised with a gonadotrophin releasing factor vaccine with surgically castrated pigs and entire boars raised under conventionally managed conditions. [2011.01]

Somatotropic axis and concentrate supplementation in grazing dairy cows of genetically diverse origin. [2011.01]

Effect of feeding fat or intrajugular infusion of glucagon-like peptide-1 and cholecystokinin on dry matter intake, digestibility, and digesta rate of passage in growing wethers. [2011.01]

Safety and tolerability of testosterone patch therapy for up to 4 years in surgically menopausal women receiving oral or transdermal oestrogen. [2011.01]

The surgical stress response and postoperative immune function after laparoscopic or conventional total mesorectal excision in rectal cancer: a randomized trial. [2011.01]

Calcitriol and doxercalciferol are equivalent in controlling bone turnover, suppressing parathyroid hormone, and increasing fibroblast growth factor-23 in secondary hyperparathyroidism. [2011.01]

Effects of recombinant human growth hormone on protein turnover in the fasting and fed state in adolescents with Crohn disease. [2011]

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