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Gastromark (Ferumoxsil) - Summary



[ferumoxsil, oral suspension]
Mallinckrodt Inc.
mL 175 μg Fe/mL

GastroMARK (ferumoxsil, oral suspension) is an aqueous suspension of silicone-coated, superparamagnetic iron oxide, intended for oral administration as a magnetic resonance imaging contrast media.

GastroMARK is indicated in adult patients for oral use with magnetic resonance imaging to enhance the delineation of the bowel to distinguish it from organs and tissues that are adjacent to the upper regions of the gastrointestinal tract.

GastroMARK’s usefulness in the lower gastrointestinal tract and retroperitoneal region is limited (by transit time and dilution).

GastroMARK is not recommended for iron supplementation.

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Published Studies Related to Gastromark (Ferumoxsil)

MR colonography with fecal tagging: barium vs. barium ferumoxsil. [2008.05]
RATIONALE AND OBJECTIVES: Both magnetic resonance (MR) and computed tomographic (CT) colonography are useful for colon examination. With sensitivities close to those for conventional colonoscopy (CC) for polyps, colonography has been proposed as an alternative to diagnostic CC. MR colonography (MRC) with fecal tagging may be a method of gaining further patient acceptance and widespread use, but the method has to be optimized. The aim of our study was to evaluate the quality of a new contrast agent mixture and to validate a new method for evaluating the tagging efficiency of contrast agents... CONCLUSION: MRC with fecal tagging using barium sulfate/ferumoxsil as contrast agent will give better overall assessment of the colon wall compared to barium sulfate alone. Furthermore, the VAS method of evaluating fecal tagging efficiency correlated with the standard method of calculating the contrast-to-wall ratio.

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Page last updated: 2008-11-03

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