Gastrografin (Diatrizoate Meglumine / Diatrizoate Sodium) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Most adverse reactions to enteral diagnostic radiopaque agents are mild and transitory. Nausea, vomiting and/or diarrhea, urticaria with erythema, hypoxia, acute dyspnea, tachyarrhythmia, and anaphylaxis have occurred following ingestion of the contrast medium, particularly when high concentrations of large volumes of solution are administered. Severe changes in serum osmolarity and electrolyte concentrations may produce shock-like states (see WARNINGS). It should be kept in mind that serious or anaphylactoid reactions that may occur with intravascular administration of radiopaque contrast agents are theoretically possible following administration by other routes.

REPORTS OF SUSPECTED GASTROGRAFIN SIDE EFFECTS / ADVERSE REACTIONS

Possible Gastrografin side effects / adverse reactions in 58 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-14

Patient: 58 year old male weighing 55.0 kg (121.0 pounds)

Reactions: Bile Output, Hypotension, Tachycardia, Blood Calcium Increased, Blood Potassium Increased, Respiratory Distress, Diarrhoea, Blood Sodium Increased, Pulseless Electrical Activity

Adverse event resulted in: death

Suspect drug(s):
Gastrografin
    Indication: Small Intestinal Obstruction
    Start date: 2011-12-06
    End date: 2011-12-06

Gastrografin
    Indication: X-RAY With Contrast Upper Gastrointestinal Tract
    Start date: 2011-12-06
    End date: 2011-12-06

Other drugs received by patient: Dilaudid; Toprol-XL; Argatroban; Methadone HCL; Insulin; Aldactone; Ativan; Decadron; Coreg

Possible Gastrografin side effects / adverse reactions in 58 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-17

Patient: 58 year old male weighing 55.0 kg (121.0 pounds)

Reactions: Bile Output, Tachycardia, Hypotension, Blood Calcium Increased, Blood Potassium Increased, Respiratory Distress, Diarrhoea, Blood Sodium Increased, Pulseless Electrical Activity

Adverse event resulted in: death

Suspect drug(s):
Gastrografin
    Indication: Small Intestinal Obstruction
    Start date: 2011-12-06
    End date: 2011-12-06

Gastrografin
    Indication: X-RAY With Contrast Upper Gastrointestinal Tract
    Start date: 2011-12-06
    End date: 2011-12-06

Other drugs received by patient: Dilaudid; Toprol-XL; Aldactone; Insulin; Methadone HCL; Decadron; Coreg; Ativan; Argatroban

Possible Gastrografin side effects / adverse reactions in 34 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-09

Patient: 34 year old female

Reactions: Aspiration

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gastrografin
    Administration route: Oral
    Indication: Oesophageal Perforation
    Start date: 2012-03-26
    End date: 2012-03-26

Gastrografin
    Administration route: Oral
    Indication: X-RAY
    Start date: 2012-03-26
    End date: 2012-03-26