NEWS HIGHLIGHTSMedia Articles Related to Gastrografin (Diatrizoate Meglumine / Diatrizoate Sodium)
New Drugs, Diagnostic Approved for Advanced Melanoma
Source: MedicineNet Melanoma Specialty [2013.05.30]
Title: New Drugs, Diagnostic Approved for Advanced Melanoma
Category: Health News
Created: 5/29/2013 6:35:00 PM
Last Editorial Review: 5/30/2013 12:00:00 AM
FDA Approves New Lung Cancer Diagnostic "Cobas EGFR Mutation Test"
Source: Lung Cancer News From Medical News Today [2013.05.15]
The U.S. Food and Drug Administration (FDA) has approved the cobas EGFR Mutation Test, a companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved companion diagnostic that detects epidermal growth factor receptor (EGFR) gene mutations, which are present in approximately 10 percent of non-small cell lung cancers (NSCLC)...
Diagnostic Errors Cause Up To 160,000 Deaths Annually, USA
Source: Litigation / Medical Malpractice News From Medical News Today [2013.04.24]
Misdiagnosing patients or making diagnostic errors is one of the most costly and dangerous mistakes made by doctors in the U.S., resulting in up to 160,000 deaths per year. Johns Hopkins researchers have reviewed over 350,000 malpractice claim payouts in the U.S over the past 25 years...
Patients Often Dissatisfied When Doctors Utilize Digital Diagnostic Tools
Source: Compliance News From Medical News Today [2013.01.29]
Health care practitioners now can access patients' data using electronic medical records, which often include information systems that assess individuals' medical histories and clinical research to facilitate doctors' diagnoses...
Brain MRIs May Provide An Early Diagnostic Marker For Dyslexia
Source: Dyslexia News From Medical News Today [2012.01.24]
Children at risk for dyslexia show differences in brain activity on MRI scans even before they begin learning to read, finds a study at Children's Hospital Boston. Since developmental dyslexia responds to early intervention, diagnosing children at risk before or during kindergarten could head off difficulties and frustration in school, the researchers say...
Published Studies Related to Gastrografin (Diatrizoate Meglumine / Diatrizoate Sodium)
Prospective randomized trial of iohexol 350 versus meglumine sodium diatrizoate as an oral contrast agent for abdominopelvic computed tomography. [2011.03]
CONCLUSION: Iohexol 350 is a satisfactory oral contrast agent for abdominopelvic CT. It opacifies the gastrointestinal tract as well as meglumine sodium diatrizoate does, and patients prefer the taste of iohexol to that of diatrizoate.
Clinical impacts of oral gastrografin follow-through in adhesive small bowel obstruction (SBO). [2010.08]
BACKGROUND: Many studies have shown that gastrografin can be used for diagnosis of adhesive small bowel obstruction (ASBO) and for assessing the need for surgical intervention. However, several studies have reported conflicting results. Therefore, the aim of this study is to assess the diagnostic and therapeutic effect of gastrografin in ASBO... CONCLUSIONS: Oral gastrografin helps in the management of ASBO. Oral gastrografin is safe and reduces the operative rate and time of resolution as well as hospital stay. Copyright 2010 Elsevier Inc. All rights reserved.
Water-soluble contrast medium (gastrografin) value in adhesive small intestine obstruction (ASIO): a prospective, randomized, controlled, clinical trial. [2008.10]
BACKGROUND: Patients with adhesive small intestine obstruction (ASIO) are difficult to evaluate and to manage and their treatment is still controversial. The diagnostic and therapeutic role of water-soluble contrast medium (Gastrografin) in ASIO is still debated. This study was designed to determine the therapeutic role of Gastrografin in patients with ASIO... CONCLUSIONS: Data showed that the use of Gastrografin in ASIO is safe and reduces the operative rate and the time to resolution of obstruction, as well as the hospital stay.
Water-Soluble Contrast Medium (Gastrografin) Value in Adhesive Small Intestine Obstruction (Asio): A Prospective, Randomized, Controlled, Clinical Trial. [2008.08.08]
BACKGROUND: Patients with adhesive small intestine obstruction (ASIO) are difficult to evaluate and to manage and their treatment is still controversial. The diagnostic and therapeutic role of water-soluble contrast medium (Gastrografin) in ASIO is still debated. This study was designed to determine the therapeutic role of Gastrografin in patients with ASIO... CONCLUSIONS: Data showed that the use of Gastrografin in ASIO is safe and reduces the operative rate and the time to resolution of obstruction, as well as the hospital stay.
Randomized controlled trial of Gastrografin in adhesive small bowel obstruction. [2005.08]
BACKGROUND: Several previous studies have shown that Gastrografin can be utilized to triage patients with adhesive small bowel obstruction (ASBO) to an operative or a non-operative course. Previous studies assessing the therapeutic effect of Gastrografin have been confounded by post-administration radiology alerting the physician to the treatment group of the patient. Therefore the aim of the present paper was to test the hypothesis that Gastrografin hastens the non-operative resolution of (ASBO)... CONCLUSIONS: Gastrografin accelerates resolution of ASBO by a specific therapeutic effect.
Clinical Trials Related to Gastrografin (Diatrizoate Meglumine / Diatrizoate Sodium)
Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery [Recruiting]
The purpose of this trial is to determine whether the water-soluble contrast (gastrografin)
is more effective in the treatment of postoperative ileus than the conventional one.
(Gastrografin Use in Small Bowel Obstruction Caused by Adherences) [Completed]
Adhesive small intestine obstruction (ASIO) is an important cause of hospital admission and a
very common disease. Any improvement in this field will benefit many patients by reducing the
operative rate. Patients with this disease are difficult to evaluate and to manage and their
treatment is controversial. Emergency surgery is mandatory when strangulation is suspected or
in the case of total obstruction. On the other hand, conservative non-operative treatment is
indicated in the case of partial obstruction. The role of water-soluble contrast medium
(Gastrografin®: GG) in ASIO is still debated with regard to the therapeutic value.
The aim of our study was to determine the therapeutic role of Gastrografin in patients with
small intestine obstruction without strangulation caused by adherences (ASIO).
Gastrografin in Postoperative Ileus [Recruiting]
After abdominal surgery there is a period of unavoidable dysfunction of the gut. During this
time patients are often unable to eat and drink, and do not pass any flatus or stool. Though
this resolves within a few days for most, there are a significant number (around 30%) who go
on to have a prolonged period of this dysfunction known clinically as postoperative ileus.
It has been clearly shown that this group of patients have worse health outcomes and spend a
longer time in hospital.
The aim of this study is to trial a drug - gastrografin - in the management of prolonged
postoperative ileus. Gastrografin is safe, economical, readily available, and has been used
with great success in the similar condition of bowel obstruction. It is predicted that
gastrografin will shorten the duration of a prolonged postoperative ileus, thus affording
affected patients a better outcome from surgery.
Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction [Recruiting]
Small bowel obstructions are responsible for 2 to 5% of emergency hospital admissions and
20% of all emergency surgical procedures. In 60 to 80% of cases, acute small bowel
obstructions are the consequence of intraperitoneal postoperative adhesions. They constitute
an extremely frequent pathology, leading to a high rate of hospital admissions and money
expense.
Management of small bowel obstruction is based on 2 options: either a surgical approach
where all patients are operating on, or a conservative treatment in which surgery is
proposed in case of failure of medical treatment. The surgical approach leads to operate on
an excessive rate of patients while the medical approach increases the risk of increased
small bowel resection, morbidity rate or hospitalization duration.
In order to improve the management of small bowel obstruction, it seems necessary to better
distinguish patients that need an emergency surgical procedure from patients in which
medical treatment will be useful. Many studies have been performed to investigate the value
of imaging in the management of small bowel obstruction, using abdominal X-ray, oral
gastrografin administration or CT-Scan.
The aim of this study is to analyse the effect of a systematic performance of imaging
investigation on the management of patients presenting with a postoperative small bowel
obstruction.
All patients suffering from a postoperative small bowel obstruction will be included in this
study. They will be randomised in 2 groups. In group S, patients will have CT-Scan and oral
water administration while in group SG, Patients will have CT-Scan and oral gastrografin
administration The major end point of this study is to analyse whether imaging examination
can reduce the need for a surgical approach or the rate of small bowel resection and to
determine its influence on fasting time or hospitalization duration
Omnipaque Versus Gastroview as Oral Contrast for Abdominal and Pelvic CT [Recruiting]
Patients who are scheduled by their health care provider for routine CT scan will be asked
to participate in this study. The primary purpose is to determine if there is a difference
in patient preference for Omnipaque versus Gastroview as oral contrast for abdominal pelvic
CT. A secondary objective is to evaluate if there is significant difference in bowel
opacification for the two agents.
Reports of Suspected Gastrografin (Diatrizoate Meglumine / Diatrizoate Sodium) Side Effects
Aspiration (3),
Tachycardia (2),
Blood Calcium Increased (2),
Blood Sodium Increased (2),
Bile Output (2),
Hypotension (2),
Blood Potassium Increased (2),
Respiratory Distress (2),
Diarrhoea (2),
Pulseless Electrical Activity (2), more >>
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