DRUG INTERACTIONS
Antibodies in GAMUNEX® may interfere with the response to live viral vaccines such as measles, mumps and rubella. Therefore, use of such vaccines should be deferred until approximately 6 months after GAMUNEX® administration. Please see DOSAGE AND ADMINISTRATION for other drug interactions.
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CONTRAINDICATIONS
GAMUNEX®, Immune Globulin Intravenous (Human), 10% Caprylate/Chromatography Purified, is contraindicated in individuals with known anaphylactic or severe systemic response to Immune Globulin (Human). Individuals with severe, selective IgA deficiencies (serum IgA <0.05 g/L) who have known antibody against IgA (anti-IgA antibody) should only receive GAMUNEX® with utmost cautionary measures, due to the risk of severe immediate hypersensitivity reactions including anaphylaxis. No experience is available on tolerability of GAMUNEX® in subjects with selective IgA deficiency since they were excluded from participation in the clinical trials with GAMUNEX®.
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