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Gabitril (Tiagabine Hydrochloride) - Published Studies

 
 



Gabitril Related Published Studies

Well-designed clinical trials related to Gabitril (Tiagabine)

Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine. [2011.02]

Tiagabine for social anxiety disorder. [2007.06]

Tiagabine does not attenuate alcohol-induced activation of the human reward system. [2007.05]

Comparison of the cognitive effects of tiagabine and carbamazepine as monotherapy in newly diagnosed adult patients with partial epilepsy: pooled analysis of two long-term, randomized, follow-up studies. [2006.07]

Long-term effects of tiagabine monotherapy on cognition and mood in adult patients with chronic partial epilepsy. [2006.06]

Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement? [2006.04.01]

Effect of tiagabine on sleep in elderly subjects with primary insomnia: a randomized, double-blind, placebo-controlled study. [2006.03.01]

Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia. [2006.03]

Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia. [2006.01.15]

The selective GABA reuptake inhibitor tiagabine for the treatment of generalized anxiety disorder: results of a placebo-controlled study. [2005.11]

Effects of tiagabine in combination with intravenous nicotine in overnight abstinent smokers. [2005.09]

Tiagabine and gabapentin for the management of chronic pain. [2005.07]

Dose-response effects of tiagabine on the sleep of older adults. [2005.06.01]

Efficacy and cognitive side effects of tiagabine and topiramate in patients with epilepsy. [2005.05]

A placebo-controlled screening trial of tiagabine, sertraline and donepezil as cocaine dependence treatments. [2005.03]

A randomised open-label study of tiagabine given two or three times daily in refractory epilepsy. [2005.03]

Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study. [2003.11]

Tiagabine for the treatment of generalized anxiety disorder: a randomized, open-label, clinical trial with paroxetine as a positive control. [2003.10]

Comparison of twice- and three times daily tiagabine for the adjunctive treatment of partial seizures in refractory patients with epilepsy: an open label, randomised, parallel-group study. [2001.06]

Tiagabine: efficacy and safety in adjunctive treatment of partial seizures. [2001.04]

The short-term impact of adjunctive tiagabine on health-related quality of life. [2001]

Tiagabine versus phenytoin and carbamazepine as add-on therapies: effects on abilities, adjustment, and mood. [2000.12]

Population pharmacokinetics of tiagabine in epileptic patients on monotherapy. [2000.09]

Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. [2000.08]

Review of controlled trials of gabitril (tiagabine): a clinician's viewpoint. [1999]

Tiagabine, a novel antiepileptic agent: lack of pharmacokinetic interaction with digoxin. [1998.06]

Development of a limited sampling approach in pharmacokinetic studies: experience with the antiepilepsy drug tiagabine. [1998.04]

A double-blind, placebo-controlled trial of tiagabine given three-times daily as add-on therapy for refractory partial seizures. Northern European Tiagabine Study Group. [1998.03]

Effects of tiagabine monotherapy on abilities, adjustment, and mood. [1998.01]

Tiagabine for complex partial seizures: a randomized, add-on, dose-response trial. [1998.01]

Tiagabine: absence of kinetic or dynamic interactions with ethanol. [1998]

Absence of interaction between tiagabine, a new antiepileptic drug, and the benzodiazepine triazolam. [1998]

[Tiagabine: a GABA-ergic anti-epileptic drug] [1997.10]

Tiagabine therapy for complex partial seizures. A dose-frequency study. The Tiagabine Study Group. [1997.05]

Cognitive and quality of life effects of differing dosages of tiagabine in epilepsy. [1997.04]

Long-term cognitive and EEG effects of tiagabine in drug-resistant partial epilepsy. [1996.11]

Pharmacokinetics of tiagabine, a gamma-aminobutyric acid-uptake inhibitor, in healthy subjects after single and multiple doses. [1995.06]

Adjunctive treatment of partial seizures with tiagabine: a placebo-controlled trial. [1995.05]

Tiagabine monotherapy in the treatment of partial epilepsy. [1995]

International experience with tiagabine add-on therapy. [1995]

Neuropsychological effects of tiagabine, a potential new antiepileptic drug. [1994.03]

Well-designed clinical trials possibly related to Gabitril (Tiagabine)

Effects of antiepileptic drugs on associative LTP-like plasticity in human motor cortex. [2010.10]

Effects of antiepileptic drugs on associative LTP-like plasticity in human motor cortex. [2010]

Seizure-free outcome in randomized add-on trials of the new antiepileptic drugs. [2007.07]

The role of anticonvulsant drugs in anxiety disorders: a critical review of the evidence. [2007.06]

Seizure-Free Outcome in Randomized Add-on Trials of the New Antiepileptic Drugs. [2007.05.23]

Pregabalin exerts oppositional effects on different inhibitory circuits in human motor cortex: a double-blind, placebo-controlled transcranial magnetic stimulation study. [2006.05]

Cocaine Rapid Efficacy Screening Trial (CREST): a paradigm for the controlled evaluation of candidate medications for cocaine dependence. [2005.03]

Trauma, resilience and saliostasis: effects of treatment in post-traumatic stress disorder. [2005.01]

Evidence-based medicine and antiepileptic drugs. [1999]

Does percent reduction in seizure frequency correlate with plasma concentration of anticonvulsant drugs? Experience with four anticonvulsant drugs. [1998.11]

Other research related to Gabitril (Tiagabine)

Tiagabine add-on for drug-resistant partial epilepsy. [2012]

Chronic tiagabine administration and aggressive responding in individuals with a history of substance abuse and antisocial behavior. [2011.07.05]

Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol. [2011.07]

An open pilot study of tiagabine in alcohol dependence: tolerability and clinical effects. [2010.09]

Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice. [2010.05]

[Therapeutic drug monitoring of tiagabine] [2010.01]

An open pilot study of tiagabine in alcohol dependence: tolerability and clinical effects. [2010]

Effects of the GABA-reuptake inhibitor tiagabine on panic and anxiety in patients with panic disorder. [2009.11]

Changes in CCK-4 induced panic after treatment with the GABA-reuptake inhibitor tiagabine are associated with an increase in 3alpha,5alpha-tetrahydrodeoxycorticosterone concentrations. [2009.11]

Effect of caffeine on the anticonvulsant effects of oxcarbazepine, lamotrigine and tiagabine in a mouse model of generalized tonic-clonic seizures. [2009.09]

Synergistic interaction of gabapentin with tiagabine in the hot-plate test in mice: an isobolographic analysis. [2009.05]

An open pilot study of tiagabine in alcohol dependence: tolerability and clinical effects. [2009.04.03]

Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis. [2009.03.01]

Increase in tiagabine serum concentration with coadministration of gemfibrozil. [2009.02]

A PET study of tiagabine treatment implicates ventral medial prefrontal cortex in generalized social anxiety disorder. [2009.01]

Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves. [2009]

Tiagabine augmentation to fluvoxamine-risperidone combination in the treatment of obsessive-compulsive disorder. [2009]

Interactions of tiagabine with ethosuximide in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves. [2008.11]

GABI-balance--a non-interventional observational study on the effectiveness of tiagabine in add-on therapy in partial epilepsy. [2008.07]

Tiagabine in adult patients with generalized anxiety disorder: results from 3 randomized, double-blind, placebo-controlled, parallel-group studies. [2008.06]

Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease. [2008.06]

Status epilepticus due to tiagabine ingestion. [2008.05]

Interactions between tiagabine and conventional antiepileptic drugs in the rat model of complex partial seizures. [2008.05]

Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats. [2008.04.01]

Effects of acute tiagabine administration on aggressive responses of adult male parolees. [2008.03]

Pilot study of lorazepam and tiagabine effects on sleep, motor learning, and impulsivity in cocaine abstinence. [2008]

A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence. [2007.12.01]

Deliberate self-poisoning with tiagabine: an unusual toxidrome. [2007.12]

[Treatment of epilepsy with third-line antiepileptic drugs: felbamate, tiagabine, and sulthiame] [2007.12]

A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence. [2007.07.13]

Influence of tiagabine on the antinociceptive action of morphine, metamizole and indomethacin in mice. [2007.05]

Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy. [2007.03.30]

Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. [2007.02.23]

The efficacy and tolerability of tiagabine in adult patients with post-traumatic stress disorder. [2007.02]

An open-label study to evaluate switching from an SSRI or SNRI to tiagabine to alleviate antidepressant-induced sexual dysfunction in generalized anxiety disorder. [2007.01]

[Tiagabine overdose--report of two cases] [2007]

Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor potentiates the anticonvulsant activity of tiagabine against pentylenetetrazol-induced convulsions in mice. [2006.12]

Effect of combined administration of ethanol and tiagabine on rabbit EEG. [2006.11]

Tiagabine in anxiety disorders. [2006.10]

Effect of the administration of tiagabine and gabapentin on rabbit electroencephalogram activity. [2006.10]

Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. [2006.08.21]

Tiagabine in the maintenance treatment of bipolar disorders. [2006.07.19]

The use of tiagabine in pediatric spasticity management. [2006.06]

Transient athetosis induced by tiagabine. [2006.04]

Tiagabine for posttraumatic stress disorder: effects of open-label and double-blind discontinuation treatment. [2006.01]

Open-label tiagabine monotherapy for major depressive disorder with anxiety. [2006.01]

Color vision and contrast sensitivity in epilepsy patients treated with initial tiagabine monotherapy. [2005.12]

A retrospective chart review comparing tiagabine and benzodiazepines for the treatment of alcohol withdrawal. [2005.12]

[GEOS (Gabitril Epilepsy Observational Study) - Polish results of the international study of tiagabine in partial epilepsy.] [2005.11]

Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia. [2005.10.28]

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