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Furosemide Injection (Furosemide) - Summary

 


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WARNING

Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose and dose schedule must be adjusted to the individual patient's needs. (See "DOSAGE AND ADMINISTRATION".)

 

SUMMARY

FUROSEMIDE
INJECTION, USP
10 mg/mL

Furosemide is a diuretic which is an anthranilic acid derivative.

Parenteral therapy should be reserved for patients unable to take oral medication or for patients in emergency clinical situations.

Furosemide is indicated in adults and pediatric patients for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Furosemide is particularly useful when an agent with greater diuretic potential is desired.

Furosemide is indicated as adjunctive therapy in acute pulmonary edema. The intravenous administration of furosemide is indicated when a rapid onset of diuresis is desired, e.g., in acute pulmonary edema.

If gastrointestinal absorption is impaired or oral medication is not practical for any reason, furosemide is indicated by the intravenous or intramuscular route. Parenteral use should be replaced with oral furosemide as soon as practical.


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NEWS HIGHLIGHTS RELATED TO FUROSEMIDE INJECTION

Published Studies Related to Furosemide Injection (Furosemide)

Randomised, placebo controlled trial of nebulised furosemide for breathlessness in patients with cancer. [2008.10]

Furosemide inhalation in dyspnea of mustard gas-exposed patients: a triple-blind randomized study. [2008.07]

Mechanisms of dyspnoea relief and improved exercise endurance after furosemide inhalation in COPD. [2008.07]

Impact of intravenous furosemide on flow rate characteristics and clinic waiting times. [2008.04]

A randomized, controlled trial of the renal effects of ultrafiltration as compared to furosemide in patients with acute decompensated heart failure. [2008.02]

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Clinical Trials Related to Furosemide Injection (Furosemide)

Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure [Completed]

The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride [Active, not recruiting]

Evaluation of Combined Action Between Natrecor and Furosemide on Kidney and Neurohormone Responses in Chronic Heart Failure: A Phase-IV study704.351 / DSS [Completed]

Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients [Completed]

Bumetanide vs. Furosemide in Heart Failure [Not yet recruiting]

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Page last updated: 2008-11-03

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