Fluvirin (Influenza Virus Vaccine) - Drug Interactions, Contraindications, Overdosage, etc

DRUG INTERACTIONS

Concomitant Administration with Other Vaccines

There are no data to assess the concomitant administration of FLUVIRIN^® with other vaccines. If FLUVIRIN^® is to be given at the same time as another injectable vaccine(s), the vaccines should always be administered at different injection sites.

FLUVIRIN ^® should not be mixed with any other vaccine in the same syringe or vial.

Concurrent Use with Immunosuppressive Therapies

Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids (used in greater than physiologic doses), may reduce the immune response to FLUVIRIN^®.

CONTRAINDICATIONS

Hypersensitivity

FLUVIRIN^® should not be administered to anyone with known systemic hypersensitivity reactions to egg proteins (eggs or egg products), or to any component of FLUVIRIN^®, or who has had a life-threatening reaction to previous influenza vaccinations.

REFERENCES

15.1 Hannoun C, Megas F, Piercy J. Immunogenicity and protective efficacy of influenza vaccination. Virus Res 2004;103:133-138.

15.2 Hobson D, Curry RL, Beare A, et. al. The role of serum hemagglutinin-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses. J Hyg Camb 1972;767-777

15.3 Centers for Disease Control and Prevention. Prevention and Control of Influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2008;57(RR-7):1-64