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Floxin (Ofloxacin) - Published Studies

 



Floxin Related Published Studies

Well-designed clinical trials related to Floxin (Ofloxacin)

Randomized controlled trial comparing oral amoxicillin-clavulanate and ofloxacin with intravenous ceftriaxone and amikacin as outpatient therapy in pediatric low-risk febrile neutropenia. [2009.09]

A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis. [2009.07]

Second-line levofloxacin-based triple schemes for Helicobacter pylori eradication. [2009.07]

Efficacy of levofloxacin-based rescue therapy for Helicobacter pylori infection after standard triple therapy: a randomized controlled trial. [2009.05]

Comparative bioavailability of two oral formulations of levofloxacin in healthy Mexican volunteers. [2009.04]

Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis. [2009.04]

Increased anterior chamber penetration of topical levofloxacin 0.5% after pulsed dosing in cataract patients. [2009.03]

Clinical and microbiological efficacy of levofloxacin administered three times a day for the treatment of bacterial conjunctivitis. [2009.01]

Safety and efficacy of intravenous tigecycline in treatment of community-acquired pneumonia: results from a double-blind randomized phase 3 comparison study with levofloxacin. [2009.01]

Tigecycline versus levofloxacin for the treatment of community-acquired pneumonia: European experience. [2008.10]

Integrated results of 2 phase 3 studies comparing tigecycline and levofloxacin in community-acquired pneumonia. [2008.07]

Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin. [2008.07]

A randomized comparative study of levofloxacin versus amoxicillin/clavulanate for treatment of infants and young children with recurrent or persistent acute otitis media. [2008.06]

A cost-minimisation analysis comparing moxifloxacin with levofloxacin plus ceftriaxone for the treatment of patients with community-acquired pneumonia in Germany: results from the MOTIV trial. [2008.05]

[Efficacy of Levofloxacin-based Triple Therapy as Second-lineHelicobacter pylori Eradication.] [2008.05]

Pharmacokinetics of antofloxacin hydrochloride, a new fluoroquinolone antibiotic, after single oral dose administration in Chinese healthy male volunteers. [2008.04]

Ocular penetration of levofloxacin, ofloxacin and ciprofloxacin in eyes with functioning filtering blebs: investigator masked, randomised clinical trial. [2008.03]

Population pharmacokinetics of levofloxacin, gatifloxacin, and moxifloxacin in adults with pulmonary tuberculosis. [2008.03]

A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis. [2008.02]

A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis. [2008.01]

Is levofloxacin necessary to prevent postoperative infections of auricular second-intention wounds? [2008.01]

A prospective randomized study to determine the efficacy of preoperative topical levofloxacin in reducing conjunctival bacterial flora. [2008.01]

[Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis] [2008.01]

Treatment for chronic prostatitis/chronic pelvic pain syndrome: levofloxacin, doxazosin and their combination. [2008]

The ocular penetration of levofloxacin 1.5% and gatifloxacin 0.3% ophthalmic solutions in subjects undergoing corneal transplant surgery. [2007.12]

A trial of levofloxacin 750 mg once daily for 5 days versus ciprofloxacin 400 mg and/or 500 mg twice daily for 10 days in the treatment of acute pyelonephritis. [2007.11]

Clinical trial: levofloxacin-based quadruple therapy was inferior to traditional quadruple therapy in the treatment of resistant Helicobacter pylori infection. [2007.10.01]

Comparative Study of Levofloxacin in the Treatment of Children With Community-Acquired Pneumonia. [2007.10]

Prospective randomized comparison of 1-day versus 3-day application of topical levofloxacin in eliminating conjunctival flora. [2007.09]

Helicobacter pylori eradication with either quadruple regimen with lactoferrin or levofloxacin-based triple therapy: a multicentre study. [2007.09]

Differential Aqueous and Vitreous Concentrations of Moxifloxacin and Ofloxacin After Topical Administration One Hour before Vitrectomy. [2007.08]

Levofloxacin-Containing Triple Therapy to Eradicate the Persistent H. pylori after a Failed Conventional Triple Therapy. [2007.08]

Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. [2007.08]

Levofloxacin 500 mg once daily versus cefuroxime 250 mg twice daily in patients with acute exacerbations of chronic obstructive bronchitis: clinical efficacy and exacerbation-free interval. [2007.07]

An open-label, randomized comparison of levofloxacin and amoxicillin/clavulanate plus clarithromycin for the treatment of hospitalized patients with community-acquired pneumonia. [2007.07]

Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial. [2007.06]

Levofloxacin vs. ciprofloxacin plus phenethicillin for the prevention of bacterial infections in patients with haematological malignancies. [2007.05]

Aqueous and vitreous penetration of levofloxacin after topical and/or oral administration. [2007.05]

[Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis] [2007.04]

Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever. [2007.03]

Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen. [2007.02.01]

Levofloxacin treatment in patients with rheumatoid arthritis receiving methotrexate. [2007.02]

Levofloxacin- vs. Ranitidine Bismuth Citrate-Containing Therapy After H. pylori Treatment Failure. [2007.02]

Open-label, randomized comparison trial of long-term outcomes of levofloxacin versus standard antibiotic therapy in acute exacerbations of chronic obstructive pulmonary disease. [2007.01]

Time of administration of a single dose of oral levofloxacin and its effect in infectious complications from transrectal prostate biopsy. [2007]

Ofloxacin otic drops vs neomycin-polymyxin B otic drops as prophylaxis against early postoperative tympanostomy tube otorrhea. [2006.12]

Moxifloxacin versus ofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: results of a multicentre, double blind, randomised trial. [2006.12]

Two open-label, randomized, crossover studies assessing the bioequivalence of ofloxacin administered as immediate-and extended-release formulations in healthy subjects. [2006.12]

Levofloxacin 750-mg for 5 days for the treatment of hospitalized Fine Risk Class III/IV community-acquired pneumonia patients. [2006.12]

Penetration of topically applied levofloxacin 0.5% and ofloxacin 0.3% into the vitreous of the non-inflamed human eye. [2006.12]

Urinary bactericidal activity of extended-release ciprofloxacin (1,000 milligrams) versus levofloxacin (500 milligrams) in healthy volunteers receiving a single oral dose. [2006.11]

Levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori eradication. [2006.09]

The effect of ofloxacin on bacillus calmette-guerin induced toxicity in patients with superficial bladder cancer: results of a randomized, prospective, double-blind, placebo controlled, multicenter study. [2006.09]

Early discharge of hospitalised patients with community-acquired urosepsis when treated with levofloxacin in sequential therapy. [2006.09]

Moxifloxacin versus levofloxacin against acute exacerbations of chronic bronchitis: the Latin American Cohort. [2006.09]

Levofloxacin 750 mg QD for five days versus amoxicillin/clavulanate 875 mg/125 mg BID for ten days for treatment of acute bacterial exacerbation of chronic bronchitis: a post hoc analysis of data from severely ill patients. [2006.08]

Altered steady state pharmacokinetics of levofloxacin in adult cystic fibrosis patients receiving calcium carbonate. [2006.08]

Can Helicobacter pylori eradication regimens be shortened in clinical practice? An open-label, randomized, pilot study of 4 and 7-day triple therapy with rabeprazole, high-dose levofloxacin, and tinidazole. [2006.07]

Pharmacokinetics of ofloxacin in broiler chicken. [2006.06]

Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis. [2006.06]

Prospective randomized study determining whether a 3-day application of ofloxacin results in the selection of fluoroquinolone-resistant coagulase-negative Staphylococcus. [2006.05]

Lansoprazole, levofloxacin and amoxicillin triple therapy vs. quadruple therapy as second-line treatment of resistant Helicobacter pylori infection. [2006.02.01]

7-day triple therapy of Helicobacter pylori infection with levofloxacin, amoxicillin, and high-dose esomeprazole in patients with known antimicrobial sensitivity. [2006.02]

Levofloxacin does not decrease mortality in Staphylococcus aureus bacteraemia when added to the standard treatment: a prospective and randomized clinical trial of 381 patients. [2006.02]

A study of 4- and 7-day triple therapy with rabeprazole, high-dose levofloxacin and tinidazole rescue treatment for Helicobacter pylori eradication. [2006.01.15]

Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE): efficacy and safety of moxifloxacin therapy versus that of levofloxacin therapy. [2006.01.01]

[Levofloxacin-Azithromycin Combined Triple Therapy for Helicobacter pylori Eradication.] [2006.01]

A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. [2006.01]

Pharmacokinetics of ciprofloxacin XR (1000mg) versus levofloxacin (500mg) in plasma and urine of male and female healthy volunteers receiving a single oral dose. [2006.01]

A randomized trial comparing the cardiac rhythm safety of moxifloxacin vs levofloxacin in elderly patients hospitalized with community-acquired pneumonia. [2005.11]

A cost-minimization analysis comparing azithromycin-based and levofloxacin-based protocols for the treatment of patients hospitalized with community-acquired pneumonia: results from the CAP-IN trial. [2005.11]

Levofloxacin- versus metronidazole-based rescue therapy for H. pylori infection in Japan. [2005.11]

Novel, single-dose microsphere formulation of azithromycin versus 7-day levofloxacin therapy for treatment of mild to moderate community-acquired Pneumonia in adults. [2005.10]

Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia. [2005.09.08]

Efficacy and safety of a novel, single-dose azithromycin microsphere formulation versus 10 days of levofloxacin for the treatment of acute bacterial sinusitis in adults. [2005.08]

Pharmacokinetics of levofloxacin after single intravenous and repeat oral administration to cats. [2005.08]

One-week once-daily triple therapy with esomeprazole, levofloxacin and azithromycin compared to a standard therapy for Helicobacter pylori eradication. [2005.08]

A multicenter, randomized, double-blind, retrospective comparison of 5- and 10-day regimens of levofloxacin in a subgroup of patients aged >/=65 years with community-acquired pneumonia. [2005.08]

Corneal penetration of fluoroquinolones: aqueous humor concentrations after topical application of levofloxacin 0.5% and ofloxacin 0.3% eyedrops. [2005.07]

Comparison of levofloxacin and cefotaxime combined with ofloxacin for ICU patients with community-acquired pneumonia who do not require vasopressors. [2005.07]

Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen. [2005.07]

Patient stratification in the management of acute bacterial exacerbation of chronic bronchitis: the role of levofloxacin 750 mg. [2005.06]

A randomized comparison of oral chloramphenicol versus ofloxacin in the treatment of uncomplicated typhoid fever in Laos. [2005.06]

Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances. [2005.04]

Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate. [2005.04]

Comparative trial of short-course ofloxacin for uncomplicated typhoid fever in Vietnamese children. [2005.03]

Levofloxacin for treatment of ventilator-associated pneumonia: a subgroup analysis from a randomized trial. [2005.02.15]

Pharmacokinetics and intrapulmonary diffusion of levofloxacin in critically ill patients with severe community-acquired pneumonia. [2005.01]

[Levofloxacin (oftaquix) a fluoroquinolone of a new generation in prevention of the postoperative endophthalmitis following uncomplicated cataract surgery--the study of the European Society of Cataract and Refractive Surgeons (ESCRS)] [2005]

Comparative bioavailability of two formulations of levofloxacin and effect of sex on bioequivalence analysis. Data from a randomised, 2 x 2 crossover trial in healthy volunteers. [2005]

Cefdinir versus levofloxacin in patients with acute rhinosinusitis of presumed bacterial etiology: a multicenter, randomized, double-blind study. [2004.12]

Levofloxacin versus clarithromycin in COPD exacerbation: focus on exacerbation-free interval. [2004.12]

Pharmacokinetics and pharmacodynamics of intravenous levofloxacin at 750 milligrams and various doses of metronidazole in healthy adult subjects. [2004.12]

[Prevention of clogging of biliary stents by administration of levofloxacin and ursodeoxycholic acid] [2004.11]

A 10-day levofloxacin-based therapy in patients with resistant Helicobacter pylori infection: a controlled trial. [2004.11]

Cost-effectiveness of full-course oral levofloxacin in severe community-acquired pneumonia. [2004.10]

Open, randomized multicenter comparative trial of rabeprazole, ofloxacin and amoxicillin therapy for Helicobacter pylori eradication: 7 vs. 14 day treatment. [2004.10]

Clinical implications of 750 mg, 5-day levofloxacin for the treatment of community-acquired pneumonia. [2004.09]

A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis. [2004.08]

Three-day application of topical ofloxacin reduces the contamination rate of microsurgical knives in cataract surgery: a prospective randomized study. [2004.07]

Ofloxacin plus rifampicin versus doxycycline plus rifampicin in the treatment of brucellosis: a randomized clinical trial [ISRCTN11871179]. [2004.06.23]

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