FINACEA SUMMARY
Finacea®
(azelaic acid) Gel, 15%
FINACEA™ (azelaic acid) Gel, 15%, contains azelaic acid, a naturally occurring saturated dicarboxylic acid.
FINACEA™ Gel, 15%, is indicated for topical treatment of inflammatory papules and pustules of mild to moderate rosacea. Patients should be instructed to avoid spicy foods, thermally hot foods and drinks, alcoholic beverages and to use only very mild soaps or soapless cleansing lotion for facial cleansing.
|
NEWS HIGHLIGHTS
Published Studies Related to Finacea (Azelaic Acid)
A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. [2009.07]
This two-phase, multicenter study was undertaken to examine the safety and efficacy of combination therapy with oral doxycycline and topical azelaic acid (AzA) 15% gel in moderate-to-severe papulopustular rosacea and to determine the effect of subsequent maintenance monotherapy with AzA 15% gel alone...
Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea. [2008.06]
BACKGROUND: Twice-daily azelaic acid (AzA) is the conventional regimen for papulopustular rosacea, but once-daily AzA may be equally effective, with greater convenience and dosing flexibility. In order to test this hypothesis, an exploratory study was conducted... CONCLUSION: Based on these findings and those of prior studies, once-daily AzA 15% gel can therefore be utilized as a safe, effective, and economical dosing option for the treatment of mild-to-moderate papulopustular rosacea. Once-daily dosing of AzA 15% gel was well accepted by patients and can offer considerable dosing flexibility and convenience for the patient as well as for the dermatologist.
Cumulative irritation potential among metronidazole gel 1%, metronidazole gel 0.75%, and azelaic acid gel 15%. [2007.04]
Topical therapy for rosacea aims to reduce inflammatory lesions and decrease erythema but can carry side effects such as stinging, pruritus, and burning... Metronidazole gel 1% had a similar profile to white petrolatum.
Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. [2006.08]
CONCLUSIONS: Azelaic acid in 20% cream and 15% gel formulations appears to be effective in the treatment of papulopustular rosacea, particularly in regard to decreases in mean inflammatory lesion count and erythema severity. Compared with metronidazole, azelaic acid appears to be an equally effective, if not better, treatment option.
Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. [2006.04]
Rosacea is an inflammatory dermatologic disorder characterized by the presence of facial erythema, visible blood vessels, papules, and pustules... On average, the efficacy (including reduction in erythema) of the once-daily application of metronidazole 1% gel and twice-daily applications of azelaic acid 15% gel were similar.
Clinical Trials Related to Finacea (Azelaic Acid)
Azelaic Acid Iontophoresis Versus Topical Azelaic Acid Cream in the Treatment of Melasma [Recruiting]
The purpose of this prospective, randomized, controlled, single-blinded investigation is to
study the efficacy, tolerability and safety of azelaic acid iontophoresis (AAI) versus
topical treatment with azelaic acid cream in female patients with melasma.
Azelaic Acid Versus Hydroquinone in Melasma [Recruiting]
Exploratory Study of Azelaic Acid 15% Foam Compared to Vehicle in Patients With Papulopustular Rosacea [Active, not recruiting]
This exploratory study is being performed to determine whether a new form formulation of
azelaic acid 15% is effective in the treatment of papulopustular rosecea.
A Study of Azelaic Acid (AzA) 15% in Topical Treatment of Mild to Moderate Perioral Dermatitis [Completed]
A Multicenter Trial of a Topical Medication for Papulopustular Rosacea Applied Twice Daily Versus Once Daily [Completed]
To assess the efficacy and tolerability of azelaic acid 15% gel applied once daily versus
twice daily in the treatment of patients with papulopustular rosacea.
|
PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 6 ratings/reviews, Finacea has an overall score of 7.50. The effectiveness score is 8 and the side effect score is 8.33. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Finacea review by 36 year old female patient | | | Rating |
| Overall rating: | |   |
| Effectiveness: | | Considerably Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | Acne |
| Dosage & duration: | | applied once a day (dosage frequency: daily) for the period of approx 3 months |
| Other conditions: | | none |
| Other drugs taken: | | birth control ON 777 | | |
Reported Results |
| Benefits: | | I started using Skinoren along with a treatment of benzoil peroxide and alpha hydroxy lotion as part of a regimen to attempt to clear up ongoing, stubborn adult acne. within about five or six days my skin started clearing up. |
| Side effects: | | My skin was already accustomed to high-percentage AHA products, so any stinging scaling or irritation were minimal. After a few days I had no side effects. |
| Comments: | | Nightly, I would put a small amount of Skinoren, Benzoil Peroxide and an AHA cream (with a 10% AHA)in the palm of my hand and combine, and apply to face nightly. The rest of my regimen included a very gentle face cleanser, and a mild and light moisturizer during the day along with an application of the 10% AHA lotion. |
|
| | Finacea review by 50 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Considerably Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | Acne |
| Dosage & duration: | | thin layer (dosage frequency: twice daily) for the period of still using |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | The occurance of medium to large acne on cheeks was almost non existant. There still was the occasional small white head and they generally healed quickly and left little to no scarring. |
| Side effects: | | There were no visible side effects that I was aware of. My only complaint was that it took about 3 months before I noticed that the occurance of medium to large pimples had stopped. |
| Comments: | | pea size amount massaged into cheeks twice daily |
|
| | Finacea review by 46 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Severe Side Effects | | |
Treatment Info |
| Condition / reason: | | ROSACEA |
| Dosage & duration: | | TWICE DAILY (dosage frequency: 6 months) for the period of 6 MONTHS |
| Other conditions: | | NONE |
| Other drugs taken: | | NONE | | |
Reported Results |
| Benefits: | | DECREASED REDNESS |
| Side effects: | | HIGHLY IRRITATED AND DRY SKIN |
| Comments: | | NONE |
|
|
|
Page last updated: 2009-10-20
|
