FINACEA SUMMARY
FINACEA® (azelaic acid) Gel, 15%, contains azelaic acid,
a naturally occurring saturated dicarboxylic acid.
FINACEA Gel, 15%, is indicated for topical treatment of inflammatory papules and
pustules of mild to moderate rosacea. Although some reduction of erythema which
was present in patients with papules and pustules of rosacea occurred in
clinical studies, efficacy for treatment of erythema in rosacea in the absence
of papules and pustules has not been evaluated. Patients should be instructed to
avoid spicy foods, thermally hot foods and drinks, alcoholic beverages and to
use only very mild soaps or soapless cleansing lotion for facial cleansing.
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NEWS HIGHLIGHTS
Published Studies Related to Finacea (Azelaic Acid)
Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne
vulgaris. [2011]
vulgaris... CONCLUSION: The profound reduction in lesion count and ASI by
Efficacy of 15% azelaic acid in psoriasis vulgaris: a randomized, controlled clinical trial. [2010.08]
BACKGROUND: Psoriasis is a common disorder affecting 1-3 percent of the general global population...
Efficacy of topical azelaic acid (AzA) gel 15% plus oral doxycycline 40 mg versus metronidazole gel 1% plus oral doxycycline 40 mg in mild-to-moderate papulopustular rosacea. [2010.06]
Rosacea is a leading reason why people seek the care of a dermatologist, accounting for nearly 7 million office visits annually. Pharmacologic treatments include both topical and oral medications, which are increasingly being used in combination, especially at the outset of therapy... These findings warrant further investigation in a sufficiently powered study.
Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. [2010.05]
INTRODUCTION: Acne vulgaris is a common problem, particularly among adolescents, which is usually resistant to monotherapy. We evaluated the efficacy and safety of a combination of azelaic acid (AA) 5% and erythromycin 2% gel (AzE) compared with AA 20% or erythromycin 2% gels in facial acne vulgaris... CONCLUSIONS: The combination of AA 5% and erythromycin 2% produced more potent therapeutic effects in comparison with erythromycin 2% or AA 20% alone, and with fewer side effects.
A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. [2009.07]
This two-phase, multicenter study was undertaken to examine the safety and efficacy of combination therapy with oral doxycycline and topical azelaic acid (AzA) 15% gel in moderate-to-severe papulopustular rosacea and to determine the effect of subsequent maintenance monotherapy with AzA 15% gel alone...
Clinical Trials Related to Finacea (Azelaic Acid)
Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study [Active, not recruiting]
The pilot study will investigate whether combination treatment of Finacea 15% Gel and
Brimonidine 0. 33% Gel could be more effective than Brimonidine 0. 33% Gel monotherapy in
treating both the papules/pustules and erythema associated with rosacea.
Combination Gel and Vascular ND in Mild to Moderate Rosacea [Completed]
The purpose of this study is to compare efficacy and outcomes of treatment with azelaic acid
(Finacea Gel) and Vascular ND: Yag laser therapy versus Vascular ND: Yag laser therapy alone
via a split face study design in approximately ten to fifteen subjects with mild to moderate
rosacea.
We hypothesize that treatment of rosacea with combination azelaic acid (Finacea Gel) and
Vascular ND: Yag laser therapy will lead to a greater improvement in lesion count, redness
and telangiectasias compared to treatment with Vascular ND: Yag laser therapy alone.
Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH) [Completed]
Residual post-inflammatory hyperpigmentation (PIH)from acne is disturbing to individuals
with skin of color. Finacea has been anecdotally known to be beneficial in resolving PIH
related to acne vulgaris. However, it has not been clinically tested for this purpose. The
current study will investigate the efficacy and safety of Finacea in the treatment of acne
vulgaris and PIH.
Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin [Completed]
The purpose of this study is to assess the effect of Skinoren® 15% gel compared to no
therapy on the maintenance of clinical therapy success in subjects with mild to moderate
acne vulgaris previously treated for 3 months by a monotherapy of this substance and to
assess the effect of Skinoren® 15% gel, compared to Differin® 0. 1% gel on the efficacy and
safety during a 9-month long-term treatment period.
Azelaic Acid Versus Hydroquinone in Melasma [Recruiting]
Reports of Suspected Finacea (Azelaic Acid) Side Effects
Burning Sensation (10),
Erythema (9),
Pruritus (6),
Skin Burning Sensation (6),
Pain (5),
Acne (5),
NO Adverse Event (5),
Skin Exfoliation (4),
Skin Discolouration (4),
Pain of Skin (4), more >>
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PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 9 ratings/reviews, Finacea has an overall score of 7.78. The effectiveness score is 8 and the side effect score is 8.67. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Finacea review by 42 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Highly Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | mild acne |
| Dosage & duration: | | very small amount over affected area (dosage frequency: am and pm) for the period of 5 months |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | the inflammation and redness around chin area was almost entirely cured, the skin was softer and smoother. |
| Side effects: | | none in my case |
| Comments: | | after applying the cream over breakout or redness at night before bed there was visible improvement over night, after a week of using the cream the breakouts were gone, skin was healed after 2 weeks. |
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| | Finacea review by 50 year old female patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Considerably Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | Acne |
| Dosage & duration: | | thin layer (dosage frequency: twice daily) for the period of still using |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | The occurance of medium to large acne on cheeks was almost non existant. There still was the occasional small white head and they generally healed quickly and left little to no scarring. |
| Side effects: | | There were no visible side effects that I was aware of. My only complaint was that it took about 3 months before I noticed that the occurance of medium to large pimples had stopped. |
| Comments: | | pea size amount massaged into cheeks twice daily |
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| | Finacea review by 46 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Moderately Effective |
| Side effects: | | Severe Side Effects | | |
Treatment Info |
| Condition / reason: | | ROSACEA |
| Dosage & duration: | | TWICE DAILY (dosage frequency: 6 months) for the period of 6 MONTHS |
| Other conditions: | | NONE |
| Other drugs taken: | | NONE | | |
Reported Results |
| Benefits: | | DECREASED REDNESS |
| Side effects: | | HIGHLY IRRITATED AND DRY SKIN |
| Comments: | | NONE |
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Page last updated: 2013-02-10
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