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Fexofenadine (Fexofenadine Hydrochloride) - Summary

 

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FEXOFENADINE SUMMARY

FEXOFENADINE HYDROCHLORIDE TABLETS

Fexofenadine hydrochloride is a histamine H1-receptor antagonist with the chemical name (±)-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-α, α-dimethyl benzeneacetic acid hydrochloride.

Seasonal Allergic Rhinitis:

Fexofenadine hydrochloride is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children 6 years of age and older. Symptoms treated effectively were sneezing, rhinorrhea, itchy nose/palate/throat, itchy/watery/red eyes.

Chronic Idiopathic Urticaria:

Fexofenadine hydrochloride is indicated for treatment of uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 years of age and older. It significantly reduces pruritus and the number of wheals.

FEXOFENADINE NEWS HIGHLIGHTS

Published Studies Related to Fexofenadine

Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis. [2007.12]

Safety and tolerability of fexofenadine for the treatment of allergic rhinitis in children 2 to 5 years old. [2007.10]

The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria. [2007.02]

Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare. [2007.01]

Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine. [2006.11]

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Clinical Trials Related to Fexofenadine

Fexofenadine (AllegraŽ) in Healthy Adults Who Have Been Identified as Slow Metabolizers for Desloratadine [Completed]

Single Center, Randomized, Double-Blind,Crossover Study Comparing Effects Of Single-Dose Fexofenadine HCl 180 mg, Cetirizine 10 mg, and Placebo on Cognitive Performance in Naval Flight Personnel [Completed]

Fasting Study of Fexofenadine Tablets 180 mg and AllegraŽ Tablets 180 mg [Completed]

Food Study of Fexofenadine Tablets 180 mg and AllegraŽ Tablets 180 mg [Completed]

Single-Center, Double-Blind, Randomized , Parallel Study Comparing Onset of Action, Efficacy & Safety of a Single-Dose of Fexofenadine HCl 180 mg vs Montelukast Na 10 mg & Placebo in Treating Seasonal Allergic Rhinitis Subjects in an Allergen Exposure Unit [Completed]

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Page last updated: 2008-03-26

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