Media Articles Related to Fareston (Toremifene)
Breast Cancer Timeline: Quiet 100 Years and Then Boom
Source: Medscape General Surgery Headlines [2015.01.29]
A timeline of developments in the treatment of breast cancer reveals great change in the past 20 to 30 years, according to two experts.
Medscape Medical News
Mayo Clinic: New breast cancer risk prediction model more accurate than current model
Source: Breast Cancer News From Medical News Today [2015.01.28]
A new breast cancer risk prediction model combining histologic features of biopsied breast tissue from women with benign breast disease and individual patient demographic information more accurately...
Lung cancer to overtake breast cancer as most fatal among European women
Source: Breast Cancer News From Medical News Today [2015.01.28]
Predictions for 2015 estimate that, for the first time, the death rates for lung cancer among women in Europe will exceed those for breast cancer.
Death rates from lung cancer will overtake those for breast cancer in 2015 among EU women
Source: Lung Cancer News From Medical News Today [2015.01.28]
Death rates from lung cancer will exceed those for breast cancer for the first time among European women in 2015, according to the latest predictions published in the leading cancer journal Annals of...
New breast exam nearly quadruples detection of invasive breast cancers in women with dense breast tissue
Source: Breast Cancer News From Medical News Today [2015.01.27]
A new breast imaging technique pioneered at Mayo Clinic nearly quadruples detection rates of invasive breast cancers in women with dense breast tissue, according to the results of a major study...
Published Studies Related to Fareston (Toremifene)
Prostate cancer diagnosis among men with isolated high-grade intraepithelial
neoplasia enrolled onto a 3-year prospective phase III clinical trial of oral
high-grade prostatic intraepithelial neoplasia (HGPIN) on biopsy... CONCLUSION: Although toremifene 20 mg did not lower the PCa detection rate, men
Toremifene to reduce fracture risk in men receiving androgen deprivation therapy
for prostate cancer. 
therapy during a 2-year period... CONCLUSIONS: Toremifene significantly decreased the incidence of new vertebral
Toremifene decreases vertebral fractures in men younger than 80 years receiving
androgen deprivation therapy for prostate cancer. 
men younger than 80 years... CONCLUSIONS: Toremifene significantly decreased new vertebral fractures in men
Toremifene to reduce fracture risk in men receiving androgen deprivation therapy for prostate cancer. [2010.10]
PURPOSE: Androgen deprivation therapy is associated with fracture risk in men with prostate cancer. We assessed the effects of toremifene, a selective estrogen receptor modulator, on fracture incidence in men receiving androgen deprivation therapy during a 2-year period... CONCLUSIONS: Toremifene significantly decreased the incidence of new vertebral fractures in men receiving androgen deprivation therapy for prostate cancer. It also significantly improved bone mineral density, bone turnover markers and serum lipid profiles. Copyright (c) 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
Effects of toremifene and tamoxifen on lipid profiles in post-menopausal patients with early breast cancer: interim results from a Japanese phase III trial. [2010.07]
OBJECTIVE: Toremifene and tamoxifen have been used for adjuvant therapy in post-menopausal patients with breast cancer in Japan. Dyslipidemias are common in post-menopausal women. However, limited data are available on the effects of these agents on lipid profiles in Japanese patients. The Japan Toremifene Cooperative Study Group has been conducting a Phase III randomized trial of post-menopausal patients with breast cancer. One of its secondary endpoints is to confirm the effects of these agents on serum lipid profiles... CONCLUSIONS: Distinct differences between two selective estrogen receptor modulators on lipids were observed. Toremifene improved lipid profiles, particularly as an enhancer of high-density lipoprotein cholesterol. To a large extent, tamoxifen improved low-density lipoprotein cholesterol levels. The impact of these improved lipid profiles on the risk of cardiovascular diseases needs further confirmation.
Clinical Trials Related to Fareston (Toremifene)
Treatment and Survival Continuation Study of Atamestane Plus Toremifene vs Letrozole in Advanced Breast Cancer [Terminated]
Protocol 777-CLP-32 is the treatment and survival continuation protocol of Biomed 777-CLP-29,
and will continue to compare combined hormonal therapy using the experimental aromatase
inhibitor (AI) atamestane combined with the FDA-approved anti-estrogen toremifene
(FarestonŽ), to the single agent FDA-approved aromatase inhibitor letrozole (FemaraŽ) for the
treatment of advanced breast cancer. The purpose of this study is to determine whether
maximal estrogen suppression achieved via the combination of atamestane, plus toremifene
(FarestonŽ), is more effective than letrozole (FemaraŽ) in delaying the growth of breast
The CAT Study: Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer [Terminated]
The purpose of this study is to determine whether maximal estrogen suppression achieved via
the combination of an experimental drug, atamestane, plus an FDA-approved drug, toremifene
(FarestonŽ), is more effective than another approved drug, letrozole (FemaraŽ), in delaying
the growth of breast cancer, and whether the side effects of the combined hormonal therapy
are different from the side effects of letrozole.
The Effect of Toremifene Treatment to the Magnetic Resonance Imaging (MRI) Findings in Premenstrual Mastalgia [Active, not recruiting]
The purpose of this study is to determine the effect of toremifene treatment to the MRI
findings of the breast in women suffering from premenstrual mastalgia.
Efficacy and Safety Study of Toremifene Citrate for the Reduction in the Risk of New Bone Fracture Occurrences in Men With Prostate Cancer [Not yet recruiting]
The purpose of this study is to determine whether Toremifene Citrate is effective in
reducing the risk of bone fractures in men with prostate cancer who are on Androgen
Antiestrogen vs Aromatase Inhibitor After Adjuvant Chemotherapy for Breast Cancer [Recruiting]
Reports of Suspected Fareston (Toremifene) Side Effects
Hepatic Function Abnormal (4),
White Blood Cell Count Decreased (4),
Interstitial Lung Disease (3),
Hepatitis Acute (2),
Condition Aggravated (2),
Respiratory Failure (2),
Neoplasm Progression (1),
Osteomyelitis (1), more >>