Media Articles Related to Evoxac (Cevimeline)
Source: MedicineNet Hoarseness Specialty [2011.09.30]
Title: Sjogren's Syndrome
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 9/30/2011 12:00:00 AM
Venus Williams Diagnosed With Sjogren's Syndrome
Source: MedicineNet Antinuclear Antibody Specialty [2011.08.31]
Title: Venus Williams Diagnosed With Sjogren's Syndrome
Category: Doctor's Views
Created: 8/31/2011 8:04:00 PM
Last Editorial Review: 8/31/2011 8:04:38 PM
Published Studies Related to Evoxac (Cevimeline)
Effectiveness of cevimeline to improve oral health in patients with postradiation
of life (QOL) in patients with xerostomia... CONCLUSIONS: Xerostomia is a significant sequela of treatment of head and neck
Comparison of the effects of pilocarpine and cevimeline on salivary flow. [2009.05]
OBJECTIVE: The aim of the present study was to compare the effect of low-dose pilocarpine and cevimeline as stimulants for salivary flow in healthy subjects... CONCLUSION: Both drugs showed efficacy in increasing the salivary flow in healthy volunteers, but cevimeline was more effective than pilocarpine.
Cevimeline (Evoxac (R)) overdose. [2011.03]
Cevimeline (Evoxac (R)) is an oral muscarinic agent that has been recently approved for the treatment of xerostomia in the setting of Sjogren's syndrome.
Dosage form design and in vitro/in vivo evaluation of cevimeline extended-release tablet formulations. [2010.01.04]
The objective of the present work is to develop an extended-release dosage form of cevimeline. Two types of extended-release tablets (simple matrix tablets and press-coated tablets) were prepared and their potential as extended-release dosage forms were assessed...
Sjogren's syndrome patients presenting with hypergammaglobulinemia are relatively unresponsive to cevimeline treatment. 
Sjogren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms, including dry eyes and dry mouth. Cevimeline is used for the treatment of dry mouth in patients with SS... It thus appears that cevimeline is effective in SS patients with milder disease activity.
Clinical Trials Related to Evoxac (Cevimeline)
Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia [Recruiting]
The purpose of this study is to determine the effectiveness of cevimeline (versus placebo)
on the oral health of patients who have dry mouth which was caused by radiation therapy that
was given for treatment of head and/or neck cancer.
Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer [Completed]
RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation
therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no
therapy in treating dry mouth caused by radiation therapy.
PURPOSE: Randomized phase III trial to determine the effectiveness of cevimeline in treating
patients who have dryness of the mouth caused by radiation therapy for head and neck cancer.
Reports of Suspected Evoxac (Cevimeline) Side Effects
Abdominal Pain Upper (2),
Localised Infection (2),
Weight Decreased (1),
Drug Interaction (1),
Chronic Obstructive Pulmonary Disease (1),
Palpitations (1), more >>