DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Evoclin (Clindamycin Phosphate Topical) - Summary

 
 



EVOCLIN SUMMARY


Evoclin® (clindamycin phosphate) Foam, 1%

Evoclin (clindamycin phosphate) Foam, 1%, a topical antibiotic in a foam vehicle, contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram in a vehicle consisting of cetyl alcohol, dehydrated alcohol (ethanol 58%), polysorbate 60, potassium hydroxide, propylene glycol, purified water, and stearyl alcohol, pressurized with a hydrocarbon (propane/butane) propellant.

Evoclin is indicated for topical application in the treatment of acne vulgaris. In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate. (See CONTRAINDICATIONS, WARNINGS, and ADVERSE REACTIONS.)


See all Evoclin indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Evoclin (Clindamycin Topical)

Laser Used to Remove Tattoos May Help Reduce Acne Scars
Source: MedicineNet Acne Specialty [2014.11.20]
Title: Laser Used to Remove Tattoos May Help Reduce Acne Scars
Category: Health News
Created: 11/20/2014 12:00:00 AM
Last Editorial Review: 11/20/2014 12:00:00 AM

Acne (Pimples)
Source: MedicineNet Boils Specialty [2014.10.17]
Title: Acne (Pimples)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 10/17/2014 12:00:00 AM

Acne Pictures Slideshow: A Visual Dictionary
Source: MedicineNet Acne Specialty [2014.10.16]
Title: Acne Pictures Slideshow: A Visual Dictionary
Category: Slideshows
Created: 10/16/2014 12:00:00 AM
Last Editorial Review: 10/16/2014 12:00:00 AM

Health Tip: Help Prevent Acne Scars
Source: MedicineNet Acne Specialty [2014.10.01]
Title: Health Tip: Help Prevent Acne Scars
Category: Health News
Created: 10/1/2014 12:00:00 AM
Last Editorial Review: 10/1/2014 12:00:00 AM

Acne (Pimples) Quiz: Test Your Medical IQ
Source: MedicineNet adapalene Specialty [2012.09.21]
Title: Acne (Pimples) Quiz: Test Your Medical IQ
Category: MedicineNet Quiz
Created: 2/28/2011 4:15:00 PM
Last Editorial Review: 9/21/2012 4:56:05 PM

more news >>

Published Studies Related to Evoclin (Clindamycin Topical)

A randomized, double-blind, placebo-controlled, pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks. [2012]
rosacea after 12 weeks of usage... CONCLUSIONS: A combination gel of clindamycin phosphate 1.2% and tretinoin 0.025%

Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. [2011.11]
BACKGROUND: Topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. Nadifloxacin, a new fluoroquinolone with anti-Propionibacterium acnes activity and additional anti-inflammatory activity, is approved for use in acne. This randomized controlled assessor blind trial compared the clinical effectiveness and safety of eight weeks therapy of nadifloxacin 1% versus clindamycin 1% as add-on therapy to benzoyl peroxide (2.5%) in mild to moderate grade acne... CONCLUSIONS: Topical nadifloxacin, a new fluoroquinolone is effective, tolerable, and safe for mild o moderate facial acne. Its clinical effectiveness is comparable to clindamycin when used as add-on therapy to benzoyl peroxide.

Efficacy of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. [2011.02]
BACKGROUND: Progressive macular hypomelanosis is a dermatosis without definite etiology. There is no consensus or first-line therapy in the treatment of progressive macular hypomelanosis, and the treatment options used are very little effective. OBJECTIVE: To evaluate the therapeutic efficacy of the topical combination of benzoyl peroxide 5% and clindamycin 1% associated with sun exposure for the treatment of progressive macular hypomelanosis... CONCLUSION: The topical combination of benzoyl peroxide 5% and clindamycin 1% is effective in the treatment of progressive macular hypomelanosis.

Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial. [2011]
It has been shown that topical linoleic acid rich-phosphatidylcholine seems to be effective in normalization of follicular hyperkeratinization, whereas nicotinamide has an interesting anti-inflammatory effect. However, little is known about their combined effect on acne.Four percentage N-PHCL cosmetic treatment resulted slightly superior to topical clindamycin with all the parameters studied for its better compliance and the global clinical improvement.

Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne vulgaris. [2011]
vulgaris... CONCLUSION: The profound reduction in lesion count and ASI by

more studies >>

Clinical Trials Related to Evoclin (Clindamycin Topical)

A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne [Recruiting]
There are many different factors that cause acne. So combination treatment using different medications that can address these different factors is commonly used to treat acne. Fixed-dose combination clindamycin phosphate 1. 2% and tretinoin 0. 025% gel and benzoyl peroxide 6% foaming cloths are both used to treat acne. This study will evaluate the use of the medications when used together.

Dalacin-T Gel Post Approval Study [Completed]

Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria [Not yet recruiting]
Few efficient drugs for malaria treatment are available so far. Due to increased exposure of these drugs and due to the high risk of development of drug resistant strains of Plasmodium falciparum, new drug combinations have to be actively investigated. The investigators will test the efficiency, safety and tolerance of combined fosmidomycin and clindamycin treatment in acute uncomplicated malaria in children aged 3-10 years.

Fosmidomycin With Clindamycin or With Clindamycin Plus Artesunate [Not yet recruiting]
The aim of this study is to evaluate the role of clindamycin and artesunate as possible combination partners for fosmidomycin to protect it from its susceptibility to recrudescent infections when used as monotherapy for acute Plasmodium falciparum malaria while retaining its excellent safety profile

Safety and Efficacy Study of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel to Treat Rosacea [Recruiting]
The purpose of this study is to determine whether Clindamycin Phosphate 1. 2% And Tretinoin 0. 025% Gel are effective and safe in the treatment of papulopustular rosacea.

more trials >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 1 ratings/reviews, Evoclin has an overall score of 5. The effectiveness score is 6 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst.
 

Evoclin review by 25 year old female patient

  Rating
Overall rating:  
Effectiveness:   Moderately Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   once a day (dosage frequency: once a day) for the period of one month
Other conditions:   blackheads, whiteheads,
Other drugs taken:   none
  
Reported Results
Benefits:   The acne cleared up but the evoclin was used in combination with proactiv. Proactiv was used before and then started getting acne again. Then I was given evoclin and used both and the acne cleared up and the whiteheads and blackheads disappeared. there was also a increase in the softness and suppleness of the facial skin.
Side effects:   As far as I know there are no side effects.
Comments:   I wash with proactiv in the morning and at night. I apply the evoclin at night only.

See all Evoclin reviews / ratings >>

Page last updated: 2014-11-20

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2014