ESTAZOLAM SUMMARY
Estazolam, a triazolobenzodiazepine derivative, is an oral hypnotic agent. Estazolam occurs as a fine, white, odorless powder that is soluble in alcohol and practically insoluble in water.
Estazolam is indicated for the short-term management of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings. Both outpatient studies and a sleep laboratory study have shown that estazolam administered at bedtime improved sleep induction and sleep maintenance (see CLINICAL PHARMACOLOGY).
Because insomnia is often transient and intermittent, the prolonged administration of estazolam is generally neither necessary nor recommended. Since insomnia may be a symptom of several other disorders, the possibility that the complaint may be related to a condition for which there is a more specific treatment should be considered.
There is evidence to support the ability of estazolam to enhance the duration and quality of sleep for intervals up to 12 weeks (see CLINICAL PHARMACOLOGY).
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NEWS HIGHLIGHTSMedia Articles Related to Estazolam
Stress, Bad Bedtime Habits Cause Insomnia Source: MedicineNet Sleep Aids And Stimulants Specialty [2009.07.27] Title: Stress, Bad Bedtime Habits Cause Insomnia Category: Health News Created: 7/25/2009 7:00:00 AM Last Editorial Review: 7/27/2009
Pills Plus Psychotherapy Can Beat Insomnia Source: MedicineNet Sleep Aids And Stimulants Specialty [2009.05.20] Title: Pills Plus Psychotherapy Can Beat Insomnia Category: Health News Created: 5/20/2009 2:00:00 AM Last Editorial Review: 5/20/2009
Insomnia Source: MedicineNet Biorhythms Specialty [2009.03.03] Title: Insomnia Category: Diseases and Conditions Created: 6/6/2005 Last Editorial Review: 3/3/2009
Insomnia Treatment: Sleep Aids and Stimulants Source: MedicineNet Narcolepsy Specialty [2009.01.14] Title: Insomnia Treatment: Sleep Aids and Stimulants Category: Diseases and Conditions Created: 9/24/1999 7:06:00 AM Last Editorial Review: 1/14/2009
Ten Tips to Avoid Insomnia and Get a Good Night's Sleep Source: MedicineNet temazepam Specialty [2008.06.05] Title: Ten Tips to Avoid Insomnia and Get a Good Night's Sleep Category: Doctor's Views Created: 6/14/2005 Last Editorial Review: 6/5/2008
Published Studies Related to Estazolam
Comparative bioavailability of two estazolam tablet formulations in Indonesian healthy volunteers. [2008] AIM: To compare the bioavailability of two estazolam (CAS 29975-16-4) tablet formulations (Estalin 2 mg tablets as test formulation and 2 mg tablets of the originator product as reference formulation)... CONCLUSION: These results indicate that two formulations of estazolam are bioequivalent and, thus, may be prescribed interchangeably.
Clinical Trials Related to Estazolam
Randomised, Double-Blind Study to Investigate the Safety and Efficacy of Brotizolam in Insomnia Outpatients. [Completed]
To investigate the efficacy and safety of Brotizolam in the treatment of patients with
insomnia in comparison with that of Estazolam
A Study to Evaluate Efficacy and Safety of Zolpidem Modified Release Formulation in Insomnia Patients [Recruiting]
The purpose of the study is to investigate the efficacy and safety of zolpidem modified
release (MR) tablet using estazolam (Eurodin) as a comparative drug in patients with primary
insomnia.
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