Erythromycin (Erythromycin Base) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The most frequent side effects of oral erythromycin preparations are gastrointestinal and are dose-related. They include nausea, vomiting, abdominal pain, diarrhea and anorexia. Symptoms of hepatitis, hepatic dysfunction and/or abnormal liver function test results may occur. (See WARNINGS.)

Onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment. (See WARNINGS.)

Erythromycin has been associated with QT prolongation and ventricular arrhythmias, including ventricular tachycardia and torsades de pointes.

Allergic reactions ranging from urticaria to anaphylaxis have occurred. Skin reactions ranging from mild eruptions to erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis have been reported rarely.

There have been rare reports of pancreatitis and convulsions.

There have been isolated reports of reversible hearing loss occurring chiefly in patients with renal insufficiency and in patients receiving high doses of erythromycin.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO ERYTHROMYCIN

Possible Erythromycin side effects / adverse reactions in 28 year old female

Reported by a physician from United Kingdom on 2007-01-15

Patient: 28 year old female

Reactions: Oligohydramnios, Intra-Uterine Death

Suspect drug(s):
Prednisolone Acetate
    Indication: Drug USE FOR Unknown Indication

Erythromycin
    Indication: Drug USE FOR Unknown Indication

Insulin
    Indication: Drug USE FOR Unknown Indication

Possible Erythromycin side effects / adverse reactions in 67 year old male

Reported by a individual with unspecified qualification from United States on 2007-01-17

Patient: 67 year old male weighing 72.2 kg (158.8 pounds)

Reactions: Hypersensitivity

Suspect drug(s):
Erythromycin

Possible Erythromycin side effects / adverse reactions in 23 year old female

Reported by a pharmacist from France on 2007-01-18

Patient: 23 year old female

Reactions: Phlebitis, Pain in Extremity, Pulmonary Embolism

Adverse event resulted in: hospitalization

Suspect drug(s):
Levothyroxine Sodium
    Administration route: Oral
    Indication: Hypothyroidism

Erythromycin
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication
    Start date: 2005-08-10
    End date: 2005-08-19