Epiquin (Hydroquinone / Retinol) - Summary

EPIQUIN SUMMARY

EpiQuin™ Micro and EpiQuin™ Micro XD contain hydroquinone USP 4% and retinol (vitamin A) incorporated into patented porous microspheres (Microsponge® * System) composed of methyl methacrylate/glycol dimethacrylate crosspolymer. This polymeric system has been shown to provide gradual release of active ingredient into the skin.¹ Hydroquinone is 1,4-benzenediol. Hydroquinone is structurally related to monobenzone. Hydroquinone occurs as fine, white needles. The drug is freely soluble in water and in alcohol and has a pK_a of 9.96.

EpiQuin Micro and EpiQuin Micro XD are indicated for the gradual treatment of ultraviolet induced dyschromia and discoloration resulting from the use of oral contraceptives, pregnancy, hormone replacement therapy, or skin trauma.

EPIQUIN NEWS HIGHLIGHTS

Published Studies Related to Epiquin (Hydroquinone / Retinol)

A comparison of triple combination cream and hydroquinone 4% cream for the treatment of moderate to severe facial melasma. [2007.03]

Cost-effectiveness of a fixed combination of hydroquinone/tretinoin/fluocinolone cream compared with hydroquinone alone in the treatment of melasma. [2007.02]

Novel approach to the treatment of hyperpigmented photodamaged skin: 4% hydroquinone/0.3% retinol versus tretinoin 0.05% emollient cream. [2005.07]

Mequinol 2%/tretinoin 0.01% solution: an effective and safe alternative to hydroquinone 3% in the treatment of solar lentigines. [2004.11]

Efficacy of hydroquinone (2%) versus tretinoin (0.025%) as adjunct topical agents for chemical peeling in patients of melasma. [2004.03]

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