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Epipen (Epinephrine Injection) - Summary

 

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EPIPEN SUMMARY

EPIPEN®
Auto-Injector for Intramuscular Injection of Epinephrine

The EpiPen® and Epipen® Jr auto-injectors contain 2 mL epinephrine injection for emergency intramuscular use. Each EpiPen® auto-injector delivers a single dose of 0.3 mg epinephrine from epinephrine injection, USP, 1:1000 (0.3 mL) in a sterile solution.

Epinephrine is indicated in the emergency treatment of allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs and other allergens as well as idiopathic or exercise-induced anaphylaxis. The EpiPen® and EpiPen® Jr auto-injectors are intended for immediate self-administration by a person with a history of an anaphylactic reaction. Such reactions may occur within minutes after exposure and consist of flushing, apprehension, syncope, tachycardia, thready or unobtainable pulse associated with a fall in blood pressure, convulsions, vomiting, diarrhea and abdominal cramps, involuntary voiding, wheezing, dyspnea due to laryngeal spasm, pruritis, rashes, uticaria or angioedema. The EpiPen® and EpiPen® Jr are designed as emergency supportive therapy only and are not a replacement or substitute for immediate medical or hospital care.

EPIPEN NEWS HIGHLIGHTS

Media Articles Related to Epipen (Epinephrine Injection)

CMAJ Study Reveals Higher Anaphylaxis Rates After HPV Vaccination
Source: Allergy News From Medical News Today [2008.09.02]

Anaphylaxis
Source: MedicineNet Allergic Cascade Specialty [2007.05.30]

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Published Studies Related to Epipen (Epinephrine Injection)

Vasopressin and epinephrine vs. epinephrine alone in cardiopulmonary resuscitation. [2008.07.03]

Epinephrine/Lidocaine injection vs. saline during endoscopic sinus surgery. [2008.07]

Treatment of common warts with an intralesional mixture of 5-fluorouracil, lidocaine, and epinephrine: a prospective placebo-controlled, double-blind randomized trial. [2008.05]

Epinephrine/Lidocaine Injection Vs. Saline During Endoscopic Sinus Surgery. [2008.04.24]

Treatment of Common Warts with an Intralesional Mixture of 5-Fluorouracil, Lidocaine, and Epinephrine: A Prospective Placebo-Controlled, Double-Blind Randomized Trial. [2008.02.06]

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Clinical Trials Related to Epipen (Epinephrine Injection)

Vasopressin and Epinephrine Versus Epinephrine Alone in Cardiac Arrest [Completed]

Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest [Completed]

Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency [Completed]

Iodine I-131 Iodocholesterol, Its Use in Adrenal Screening [Completed]

Effects of Epinephrine and Intravenous (I.V.) Needle on Cardiopulmonary Resuscitation (CPR) Outcome [Completed]

more>>

Page last updated: 2008-09-02

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