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Epiflur TM (Sodium Fluoride) - Description and Clinical Pharmacology

 
 



DESCRIPTION:

Each Epiflur™ (sodium fluoride) Tablet is sugar free, saccharine free and erythrosine (FD&C Red Dye #3) free. Each Epiflur™ Tablet 1 mg F* (full-strength) contains 1 mg fluoride ion (F*) from 2.2 mg sodium fluoride (NaF). Each Epiflur™ Tablet 0.5 mg (half-strength) contains 0.5 mg F* from 1.1 mg sodium fluoride (NaF). Each Epiflur™ Tablet 0.25 mg (quarter-strength) contains 0.25 mg F* from 0.55 mg sodium fluoride (NaF).

Each tablet for oral administration contains sodium fluoride equivalent to fluoride 0.25 mg, 0.5 mg or 1 mg and the following inactive ingredients: microcrystalline cellulose, maltodextrin, sorbitol, colloidal silicon dioxide, natural and artificial vanilla flavored powder and magnesium stearate. In addition, the 0.5 mg tablet contains purple lake blend and the 1 mg tablet contains pink lake blend.

CLINICAL PHARMACOLOGY:

Sodium fluoride acts systemically (before tooth eruption) and topically (post eruption) by increasing tooth resistance to acid dissolution, by promoting remineralization, and by inhibiting the cariogenic microbial process.

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