The action of nondepolarizing relaxants is augmented by enflurane. Less than the usual amounts of these drugs should be used. If the usual amounts of nondepolarizing relaxants are given, the time for recovery from neuromuscular blockade will be longer in the presence of enflurane than when halothane or nitrous oxide with a balanced technique are used
OVERDOSAGE
In the event of overdosage, or what may appear to be overdosage, the following action should be taken: Stop drug administration, establish a clear airway and initiate assisted or controlled ventilation with pure oxygen.
CONTRAINDICATIONS
Seizure disorders (see WARNINGS) Known sensitivity to Enflurane or other halogenated anestheticsKnown or suspected genetic susceptibility to malignant hyperthermia