NEWS HIGHLIGHTSMedia Articles Related to Emla (Prilocaine / Lidocaine Topical)
Abdominal Surgery Without General Anesthesia Source: GastroIntestinal / Gastroenterology News From Medical News Today [2009.11.04] A recent review in Faculty of 1000 Medicine Reports, a publication in which clinicians highlight advances in medical practice, suggests regional pain relief could be used during abdominal surgery. In this review, Michael Schaefer recommends a new approach that can be performed without the need for general anaesthetics.
Anesthesia, Exertional Heat Deaths May Be Linked Source: MedicineNet Hyperthermia Specialty [2009.10.26] Title: Anesthesia, Exertional Heat Deaths May Be Linked Category: Health News Created: 10/23/2009 4:10:00 PM Last Editorial Review: 10/26/2009
Anesthesia in Youngest Kids May be Linked to Learning Disabilities Source: MedicineNet Hernia Specialty [2009.03.25] Title: Anesthesia in Youngest Kids May be Linked to Learning Disabilities Category: Health News Created: 3/25/2009 2:00:00 AM Last Editorial Review: 3/25/2009
Need For Emergency Airway Surgery For Hard-to-Intubate Patients Reduced Source: Respiratory / Asthma News From Medical News Today [2009.11.18] Be prepared, that old Boy Scout motto, is being applied with great success to operating room patients whose anatomy may make it difficult for physicians to help them breathe during surgery, Johns Hopkins researchers report in a new study. When patients undergo general anesthesia, they stop breathing on their own and anesthesiologists must quickly insert a tube into the airway as a first step in machine-assisted breathing.
New Technique For Injectable Facial Fillers Improves Comfort, Recovery Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today [2009.10.29] Less pain during injections for wrinkle-fighting facial fillers. Less swelling afterward. Less time in the office waiting for anesthesia to take effect. These and other benefits of a new injection technique that UT Southwestern Medical Center plastic surgeons are helping pioneer are outlined in the October issue of Plastic and Reconstructive Surgery.
Published Studies Related to Emla (Prilocaine / Lidocaine Topical)
Comparison between lidocaine-prilocaine cream (EMLA) and mepivacaine infiltration for pain relief during perineal repair after childbirth: a randomized trial. [2009.08] OBJECTIVE: The purpose of this study was to compare the effectiveness of topically applied lidocaine-prilocaine (EMLA) cream with local anesthetic infiltration in the reduction of pain during perineal suturing after childbirth... CONCLUSION: EMLA cream appears to be an effective and satisfactory alternative to local anesthetic infiltration for the relief of pain during perineal repair.
A clinical comparison of topical piroxicam and EMLA cream for pain relief and inflammation in laser hair removal. [2009.07] The aim of this study was to compare the efficacy of topical piroxicam and EMLA cream on pain control and subsequent inflammation in neodymium:yttrium-aluminum-garnet (Nd:YAG) 1,064 nm laser hair removal in female volunteers. Fifty female volunteers were enrolled in this prospective, randomized, double-blind, clinical study over a 6-month period...
Pregnancy at term does not alter the responses to a mechanical and an electrical stimulus after skin EMLA application. [2009.06] BACKGROUND: Pregnancy is associated with reduced local anesthetic requirements and increased pain thresholds, possibly due to hormonal changes and activation of endogenous opioids... CONCLUSIONS: Late pregnancy is not associated with increased sensitivity to local anesthetics (EMLA) applied to the skin, under our study conditions.
The influence of a eutectic mixture of lidocaine and prilocaine on minor surgical procedures: a randomized controlled double-blind trial. [2009.06] BACKGROUND: A eutectic mixture of lidocaine and prilocaine (EMLA) has been shown to be effective in reducing pain from needle sticks, including those associated with blood sampling and intravenous insertion. OBJECTIVE: To evaluate the effectiveness of EMLA cream applied before needle puncture for local anesthetic administration before minor surgical procedures in this double-blind, randomized, controlled, parallel-group study... CONCLUSION: EMLA effectively reduces the preprocedural needle-stick pain and procedural pain associated with minor surgical procedures.
A comparison between EMLA cream application versus lidocaine infiltration for postoperative analgesia after inguinal herniotomy in children. [2009.03] BACKGROUND: EMLA cream (eutectic mixture of local anesthetics) has been shown to penetrate intact skin and provide analgesia of superficial layers. There are no studies on the effects of topical application of EMLA cream for postoperative pain relief after inguinal hernia repair. OBJECTIVE:: This randomized, double-blind, placebo-controlled study compared the efficacy of topical application of 5% EMLA cream before surgery, with wound infiltration with 1% lidocaine for postoperative analgesia in children... CONCLUSION: Topical application of EMLA (5%) provides postoperative analgesia comparable to infiltration with 1% lidocaine after inguinal hernia repair in children.
Clinical Trials Related to Emla (Prilocaine / Lidocaine Topical)
Study of Fentanyl-Propofol-EMLA of L.M.X4 Technique for Bone Marrow Aspiration [Active, not recruiting]
St. Jude Children's Research Hospital is studying the best ways to prevent pain during and
after procedures such as bone marrow aspiration and lumbar puncture with intrathecal (in the
spinal fluid) chemotherapy. Researchers will study the effectiveness of combining anesthetics
(medicines that help people sleep) and analgesics (medicines that relieve pain). Researchers
believe that a combination of fentanyl (analgesic) and propofol (anesthetic), along with
applying the skin-numbing-cream EMLA or L. M.X4™ on the area where the procedure is performed,
will provide better pain control.
Each patient enrolled on this study will have three different anesthetic combinations for
three different procedures, in order to determine which combination worked best for each
child.
Evaluation of Analgesia With EMLA and Glucose Oral Solution in Preterm Neonates During Arterial Puncture and PICC Installation [Recruiting]
Improvement of Sensibility in the Foot in Diabetic Patients Induced by EMLA-application to the Lower Leg [Recruiting]
Sensory input from the foot as well as all other body parts results in activation of sensory
cortex.
It is well known that the cortical body map is experienced-dependant and can rapidly change
in response to changes in activity and sensory input from the periphery [10-12]. Increased
activity and sensory input from the hand results in expansion of the cortical hand
representation [13-15], while decreased sensory input, for instance by anaesthesia,
amputation or nerve injury, results in shrinkage of the cortical hand representation
[16-21]. Due to the constant ongoing "cortical competition" between body parts the adjacent
cortical areas expand and take over the silent area, deprived of sensory input.
The investigators have recently described striking examples of such rapid cortical
re-organisations induced by selective cutaneous anaesthesia of the forearm: application of
EMLA cream to the volar aspect of the forearm results in improved sensory functions of the
hand [18] linked to expansion of the hand representational area in sensory cortex . In
analogy, EMLA application to the lower leg in healthy controls results in improved sensory
functions in the sole of the foot linked to expansion of the foot representational area in
sensory cortex.
To test the hypothesis that EMLA application to the lower leg of diabetic patients will
result in improved sensory functions in the sole of the foot as well as expansion of the
foot representation in sensory cortex. The investigators hypothesize that repeated
applications of EMLA will result in a long lasting sensibility improvement.
Randomised Trial of Eutectic Mixture of Local Anaesthetics Cream and Oral Sucrose Solution for Venepuncture [Not yet recruiting]
This randomized bicentric trial will investigate the efficacy of topical EMLA cream with
oral sucrose solution compared to oral sucrose solution alone before venepuncture in preterm
infants.
The Efficacy of EMLA Cream vs. Synera Patch for Pain Reduction During Venipuncture in Children [Recruiting]
The objective of this study is to compare the efficacy of the Synera patch applied for 20
minutes with the efficacy of EMLA Cream applied for 60 minutes in reducing pain associated
with venipunctures in children.
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