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Elspar (Asparaginase) - Drug Interactions, Contraindications, Overdosage, etc



ELSPAR drug label information in our database does not contain a dedicated section on drug interactions. Please check subsections of WARNINGS AND PRECAUTIONS as well as other sources.


The acute intravenous LD50 of ELSPAR for mice was about 500,000 I.U./kg and for rabbits about 22,000 I.U./kg.


ELSPAR is contraindicated in patients with pancreatitis or a history of pancreatitis. Acute hemorrhagic pancreatitis, in some instances fatal, has been reported following asparaginase administration. Asparaginase is also contraindicated in patients who have had previous anaphylactic reactions to it.

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