ELOXATIN™
(oxaliplatin for injection)
DESCRIPTION
ELOXATIN™ (oxaliplatin for injection) is an antineoplastic agent with the molecular formula C8H14N2O4Pt and the chemical name of cis -[(1 R,2 R)-1,2-cyclohexanediamine- N,N '] [oxalato(2-)- O,O '] platinum. Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane(DACH) and with an oxalate ligand as a leaving group.
The molecular weight is 397.3. Oxaliplatin is slightly soluble in water at 6 mg/mL, very slightly soluble in methanol, and practically insoluble in ethanol and acetone. ELOXATIN is supplied in vials containing 50 mg or 100 mg of oxaliplatin as a sterile, preservative-free lyophilized powder for reconstitution. Lactose monohydrate is present as an inactive ingredient at 450 mg and 900 mg in the 50 mg and 100 mg dosage strengths, respectively.
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