Eloxatin (Oxaliplatin) - Summary

ELOXATIN SUMMARY

ELOXATIN™
(oxaliplatin for injection)

ELOXATIN^™ (oxaliplatin for injection) is an antineoplastic agent. Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate ligand as a leaving group.

ELOXATIN, used in combination with infusional 5-FU/LV, is indicated for the treatment of advanced carcinoma of the colon or rectum.

ELOXATIN NEWS HIGHLIGHTS

Media Articles Related to Eloxatin (Oxaliplatin)

Vectibix(R) Now Available For The Treatment Of Advanced Colorectal Cancer In Belgium
Source: Colorectal Cancer News From Medical News Today [2008.10.03]

Colonoscopy Associated With Reduced Colorectal Cancer Incidence
Source: Colorectal Cancer News From Medical News Today [2008.10.03]

Gene Variation Associated With Decreased Risk Of Colorectal Cancer
Source: Colorectal Cancer News From Medical News Today [2008.10.02]

DNA Direct Announces Availability Of ColoSure(TM) Colorectal Cancer Screening Test
Source: Colorectal Cancer News From Medical News Today [2008.10.02]

New Option For Some Colorectal Cancer Patients
Source: Colorectal Cancer News From Medical News Today [2008.10.01]

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Published Studies Related to Eloxatin (Oxaliplatin)

EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. [2008.05.10]

Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. [2008.04.20]

Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. [2008.04.20]

A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity. [2008.04]

Randomized, multicenter, phase IIb study of preoperative chemoradiotherapy in T3 mid-distal rectal cancer: raltitrexed + oxaliplatin + radiotherapy versus cisplatin + 5-fluorouracil + radiotherapy. [2008.02.01]

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Clinical Trials Related to Eloxatin (Oxaliplatin)

XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer [Active, not recruiting]

Oxaliplatin and Capecitabine in Patients With Unresectable Cholangiocarcinoma [Active, not recruiting]

A Phase II Study of Eloxatin and Alimta in Combination With Bevacizumab in Advanced Non-Squamous NSCLC [Active, not recruiting]

Endometrial Cancer - LOHP Alone and With 5FU [Completed]

Study of Capecitabine With Irinotecan and Oxaliplatin (Eloxatin) in Advanced Colorectal Cancer [Active, not recruiting]

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