Media Articles Related to Edluar (Zolpidem)
Insomniacs May Be More Sensitive to Pain
Source: MedicineNet Chronic Pain Specialty [2015.05.13]
Title: Insomniacs May Be More Sensitive to Pain
Category: Health News
Created: 5/12/2015 12:00:00 AM
Last Editorial Review: 5/13/2015 12:00:00 AM
Study links insomnia to impaired work performance in night shift workers
Source: Sleep / Sleep Disorders / Insomnia News From Medical News Today [2015.04.30]
A new study of night shift workers suggests that overnight occupational and cognitive impairment is more strongly correlated to insomnia than it is to sleepiness.
Source: MedicineNet Creutzfeldt-Jakob Disease Specialty [2014.07.17]
Category: Diseases and Conditions
Created: 6/6/2005 12:00:00 AM
Last Editorial Review: 7/17/2014 12:00:00 AM
Shift work linked to sleep problems, poor metabolic health
Source: Diabetes News From Medical News Today [2015.05.18]
A new study finds people who work shifts are more likely to experience sleep problems such as insomnia, which may increase their risk of obesity and diabetes.
Impaired sleep linked to lower pain tolerance
Source: Sleep / Sleep Disorders / Insomnia News From Medical News Today [2015.05.04]
People with insomnia and other sleep problems have increased sensitivity to pain, reports a study published in PAIN®, the official publication of the International Association for the Study of...
Published Studies Related to Edluar (Zolpidem)
Efficacy and safety of a polyherbal sedative-hypnotic formulation NSF-3 in
primary insomnia in comparison to zolpidem: a randomized controlled trial. 
insomnia... CONCLUSIONS: NSF-3 is a safe and effective short-term alternative to zolpidem for
Novel sublingual low-dose zolpidem tablet reduces latency to sleep onset
following spontaneous middle-of-the-night awakening in insomnia in a randomized,
double-blind, placebo-controlled, outpatient study. 
to sleep after MOTN awakenings... CONCLUSIONS: 3.5 mg ZST used as needed significantly reduced latency to return to
Improved insomnia symptoms and sleep-related next-day functioning in patients with comorbid major depressive disorder and insomnia following concomitant zolpidem extended-release 12.5 mg and escitalopram treatment: a randomized controlled trial. [2011.07]
CONCLUSIONS: Zolpidem extended-release administered concomitantly with escitalopram for up to 24 weeks was well tolerated and improved insomnia and some sleep-related next-day symptoms and next-day functioning in patients with MDD but did not significantly augment the antidepressant response of escitalopram. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00296179. (c) Copyright 2011 Physicians Postgraduate Press, Inc.
The use of a non-benzodiazepine hypnotic sleep-aid (Zolpidem) in patients undergoing ACL reconstruction: a randomized controlled clinical trial. [2011.05]
PURPOSE: Previous studies have addressed post-operative pain management after ACL reconstruction by examining the use of intra-articular analgesia and/or modification of anesthesia techniques. To our knowledge, however, no previous studies have evaluated the effect of zolpidem on post-operative narcotic requirements, pain, and fatigue in patients undergoing outpatient arthroscopic ACL reconstruction. The purpose of this prospective, blinded, randomized, controlled clinical study was to evaluate the effect of zolpidem on post-operative narcotic requirements, pain, and fatigue in patients undergoing outpatient arthroscopic ACL reconstruction... CONCLUSION: Adding zolpidem to the post-operative medication regimen after arthroscopic ACL reconstruction helps to lower the amount of narcotic pain medication required for adequate analgesia. LEVEL OF EVIDENCE: Randomized controlled clinical trial, Level I.
Zolpidem and zopiclone impair similarly monotonous driving performance after a single nighttime intake in aged subjects. [2011.04]
RATIONALE: Although hypnotics are primarily used by older people, the residual effects the morning after a single nighttime intake of the two most commonly prescribed hypnotics, zolpidem (Zp) and zopiclone (Zc), on older middle-aged drivers have not been evaluated and compared... CONCLUSIONS: This is the first study revealing residual effects of Zp on driving performance in ageing drivers which are similar to that of Zc. Studying the effects of medication in different age ranges appears useful to complete the studies on behavioural-pharmacological effects of medication. To reduce the incidence of driving accidents due to prescription drugs, patients should be warned at the time of treatment initiation that they should avoid driving.
Clinical Trials Related to Edluar (Zolpidem)
A Study to Compare Efficacy and Safety of Zolpidem Modified Release Formulation Versus Zolpidem in Insomnia Patients [Recruiting]
The purpose of this study is to investigate the efficacy and safety of zolpidem MR (modified
release) compared to zolpidem IR (immediate release) in patients with primary insomnia.
Zolpidem CR and Hospitalized Patients With Dementia [Recruiting]
The purpose of this research study is to compare the effectiveness of Zolpidem CR to that of
placebo in improving sleep efficiency in people with dementia admitted to the hospital
because of their symptoms. You can participate in this study if you have dementia of the
Alzheimer's type or vascular dementia. This study involves placebo; a placebo is a tablet
that looks exactly like Zolpidem CR, the study drug, but contains no active study drug. We
will use placebos to see if the study results are due to the study drug or due to other
reasons. Zolpidem CR is also called Ambien CR and is widely available by prescription.
Zolpidem CR is approved by the U. S. Food and Drug Administration (FDA) for the short-term
treatment of insomnia (trouble falling or staying asleep).
Use of Zolpidem in Parkinson's Disease [Not yet recruiting]
Levodopa treatment is associated with long-term complications. Dopamine deficiency is
associated with abnormal activity in certain parts of the brain. Zolpidem may change this
abnormal activity and, by doing so, may work in a different way than levodopa to help
The working hypothesis for this aim is that ZLP is superior to placebo in acutely improving
motor symptoms of PD. The investigators will conduct a randomized,controlled, double-blind,
cross-over study in 40 patients with PD. Each patient will receive placebo, levodopa and 2
doses of ZLP in a randomized order on 4 different occasions, about one week apart.
A Study to Evaluate Efficacy and Safety of Zolpidem Modified Release Formulation in Insomnia Patients [Recruiting]
The purpose of the study is to investigate the efficacy and safety of zolpidem modified
release (MR) tablet using estazolam (Eurodin) as a comparative drug in patients with primary
Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet [Recruiting]
A study in healthy volunteers of the next morning driving performance after
middle-of-the-night dosing of 3. 5 mg zolpidem tartrate sublingual tablet, a sleep aid. The
next morning driving performance will be measured by taking a standardized driving test.