Edecrin Related Published Studies
Well-designed clinical trials related to Edecrin (Ethacrynic Acid)
A comparison of the effects of inhaled furosemide and ethacrynic acid on sodium-metabisulfite-induced bronchoconstriction in subjects with asthma. [1995.02]
Pharmakokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer. [1994.09]
Alternating sequential dosing with furosemide and ethacrynic acid in drug tolerance in the newborn. [1989.07]
Well-designed clinical trials possibly related to Edecrin (Ethacrynic Acid)
Ototoxic drugs and sensorineural hearing loss following severe neonatal respiratory failure. [2006.02]
Other research related to Edecrin (Ethacrynic Acid)
Effects of the new ethacrynic acid oxime derivative SA12590 on intraocular pressure in cats and monkeys. [2007.08]
Cell death after co-administration of cisplatin and ethacrynic acid. [2007.04]
Effects of novel ethacrynic acid derivatives on human trabecular meshwork cell shape, actin cytoskeletal organization, and transcellular fluid flow. [2005.12]
Novel antiglaucoma prodrugs and codrugs of ethacrynic acid. [2005.08.01]
Clofibric and ethacrynic acids prevent experimental pyelonephritis by Escherichia coli in mice. [2004.11.01]
Controlled release of ethacrynic acid from poly(lactide-co-glycolide) films for glaucoma treatment. [2004.08]
Ethacrynic acid can be effective for refractory congestive heart failure and ascites. [2003.11]
Late dosing with ethacrynic acid can reduce gentamicin concentration in perilymph and protect cochlear hair cells. [2003.11]
Effect of ethacrynic acid on sodium pump alpha isoforms in SH-SY5Y cells. [2003.04]
Ethacrynic acid rapidly and selectively abolishes blood flow in vessels supplying the lateral wall of the cochlea. [2002.11]
Effects of ethacrynic acid on intraocular pressure of anesthetized rats. [1999.03]
Topical gentamicin and ethacrynic acid: effects on cochlear function. [1998.07]
Effects of chronic ethacrynic acid exposure on glutathione conjugation and MRP expression in human colon tumor cells. [1996.05.06]
Effect of daily topical ethacrynic acid on aqueous humor dynamics in monkeys. [1995.09]
Effects of topical ethacrynic acid ointment vs timolol on intraocular pressure in glaucomatous monkey eyes. [1994.03]
Effect of ethacrynic acid on aqueous outflow dynamics in monkeys. [1994.03]
Partial hearing loss in the macaque following the co-administration of kanamycin and ethacrynic acid. [1994.01]
Reversing of chlorambucil resistance by ethacrynic acid in a B-CLL patient. [1993.10]
[Experimental study on the therapeutic value of microwave on hearing loss due to ethacrynic acid ototoxicity] [1993]
[Measurement of the concentrations of PGF2 alpha and PG12 in the cochlear lateral wall of guinea pigs following intravenous injection of ethacrynic acid] [1993]
Effect of buthionine sulfoximine and ethacrynic acid on cytotoxic activity of mitomycin C analogues BMY 25282 and BMY 25067. [1992.12.01]
The effect of intracameral ethacrynic acid on the intraocular pressure of living monkeys. [1992.06.15]
The effect of intracamerally injected ethacrynic acid on intraocular pressure in patients with glaucoma. [1992.05.15]
Effects of topical ethacrynic acid adducts on intraocular pressure in rabbits and monkeys. [1992.05]
A study of ethacrynic acid as a potential modifier of melphalan and cisplatin sensitivity in human lung cancer parental and drug-resistant cell lines. [1992.05]
Cellular and subcellular localization of tritiated gentamicin in the guinea pig cochlea following combined treatment with ethacrynic acid. [1992.01]
Physiologic and rheologic effects of the antisickling agent ethacrynic acid and its N-butylated derivative on normal and sickle erythrocytes. [1992.01]
Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid. [1991.11.15]
The initial-rate kinetics of mouse glutathione S-transferase YfYf. Evidence for an allosteric site for ethacrynic acid. [1991.05.01]
Ethacrynic acid-induced convulsions and brain noradrenaline in mice. [1990.04.10]
Stimulation of renin release by PGE2 and PGI2 infusion in the dog: enhancing effect of ureteral occlusion or administration of ethacrynic acid. [1990.02]
Intracerebroventricular injection of ethacrynic acid induces status epilepticus. [1989.07.04]
Effects of ureteral occlusion and ethacrynic acid infusion on renal prostaglandin degradation in the dog. [1988.08]
Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. [1988.07.01]
Other possibly related research studies
Chinchilla models of selective cochlear hair cell loss. [2002.12]
[The role of thiol oxidants in inhibition of pancreatic exocrine secretory function and glutathione] [2002.05]
Intra-cochlear administration of dexamethasone attenuates aminoglycoside ototoxicity in the guinea pig. [2002.05]
Solutol and cremophor products as new additives in suppository formulation. [2002]
Cellular sensitivity determinants to docetaxel in human gastrointestinal cancers. [2002.02]
Induction of glutathione S-transferase activity and protein expression in brown bullhead (Ameiurus nebulosus) liver by ethoxyquin. [2001.07]
Glial cell line-derived neurotrophic factor. Potential for otoprotection. [1999.11.28]
Agents which block potassium-chloride cotransport prevent sound-triggered seizures in post-ischemic audiogenic seizure-prone rats. [2000.05.02]
Glutathione S-transferase in human endometrium: quantitation and interindividual variability in isoform content. [1999]
Coordinate changes in expression of protective genes in drug-resistant cells. [1998.04.24]
The effects of different antineoplastic agents and of pretreatment by modulators on three melanoma lines. [1998.02.01]
Importance of glutathione and associated enzymes in drug response. [1997]
Bioelectrical cochlear noise and its contralateral suppression: relation to background activity of the eighth nerve and effects of sedation and anesthesia. [1997.09]
Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme. [1997.05.20]
Preclinical and clinical development of dexketoprofen. [1996]
Onset of ototoxicity in the cat is related to onset of auditory function. [1995.12]
Depletion of cytosolic GSH decreases the ATP levels and viability of synaptosomes from aged mice but not from young mice. [1995.09.29]
Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells. [1995.05.26]
Modulation of glutathione and related enzymes in reversal of resistance to anticancer drugs. [1995.04]
Cochlear pathology following chronic electrical stimulation of the auditory nerve: II. Deafened kittens. [1994.12]
Pharmacological advances in the treatment of glaucoma. [1994.09]
Continuous infusion of loop diuretics in the critically ill: a review of the literature. [1994.08]
Ototoxicity of loop diuretics. [1993.10]
A newly synthesized bifunctional inhibitor, W-77, enhances adriamycin activity against human ovarian carcinoma cells. [1993.05.01]
Multifactorial molecular mechanisms are involved in resistance of preirradiated human cervix carcinoma cells to cis-dichlorodiammineplatinum (II) and vincristine. [1993]
[The indications and need for diuretics in pregnancy] [1992.10]
Sensitization of drug resistant human ovarian cancer cells to cyanomorpholino doxorubicin (MRA-CN) by modulation of glutathione metabolism. [1992]
[Deafness, induced by sodium ethacrynate in guinea pigs, alleviated by microwave treatment] [1992]
Effects on cochlear morphology of repeated insults to the stria vascularis. [1991.07]
Protective effect of electrical stimulation in the deafened guinea pig cochlea. [1991.03]
Comparative acute ototoxicity of loop diuretic compounds. [1991]
[Synergism between noise and ototoxic drugs: new experimental data] [1990.10]
Screening procedure for assessment of ototoxicity in the common marmoset. [1990.08]
Cisplatin: nephrotoxic action in vertebrates and its prevention. [1989]
Characterization of antibody and selection of alternative drug therapy in hydrochlorothiazide-induced immune hemolytic anemia. [1988.01]
Effect of agents which alter the Na transport on the sodium appetite in rats. [1987.12]
Mechanism of osmotic diuresis studied by infusion of NaHCO3 and mannitol in dogs. [1987.11]
Diuretic synergy in the treatment of acute experimental cerebral edema. [1971.02]
Augmentation of cisplatin sensitivity in cisplatin-resistant human bladder cancer cells by modulating glutathione concentrations and glutathione-related enzyme activities. [2005.05]
The influence of anti-irritants on captopril hydrophilic gel. [2004.02]
Risk of hospitalization for upper gastrointestinal tract bleeding. [2004.01]
Antioxidant gene therapy can protect hearing and hair cells from ototoxicity. [2004.02]
Induction of cytosolic glutathione S-transferases from Atlantic eel (Anguilla Anguilla) after intraperitoneal treatment with polychlorinated biphenyls. [2002.10.07]
Effects of cigarette smoke with different tar contents on hepatic and pulmonary xenobiotic metabolizing enzymes in rats. [2002.01]
Dietary fat and garlic oil independently regulate hepatic cytochrome p(450) 2B1 and the placental form of glutathione S-transferase expression in rats. [2001.05]
The three mechanisms of intracellular chloride accumulation in vascular smooth muscle of human umbilical and placental arteries. [2000.11]
Insights into ototoxicity. Analogies to nephrotoxicity. [1999.11.28]
Effects of some probable antioxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats. [1999.12.06]
An approach to optimizing the active site in a glutathione transferase by evolution in vitro. [1999.11.15]
Prolonged use of pancuronium bromide and sensorineural hearing loss in childhood survivors of congenital diaphragmatic hernia. [1999.08]
cis-urocanic acid induces mast cell degranulation and release of preformed TNF-alpha: A possible mechanism linking UVB and cis-urocanic acid to immunosuppression of contact hypersensitivity. [1999.01]
Glutathione S-transferases in wild-type and doxorubicin-resistant MCF-7 human breast cancer cell lines. [1999.02]
University of Miami Division of Clinical Pharmacology Therapeutic Rounds: managing hypertension in patients with kidney disease-implications for preservation of renal function. [1998.09]
Effect of ticrynafen on aqueous humor dynamics in monkeys. [1998.11]
Pseudoporphyria cutanea tarda induced by furosemide in a patient undergoing peritoneal dialysis. [1998]
Cloning, expression and characterization of an insect class I glutathione S-transferase from Anopheles dirus species B. [1998.05]
Isolation and characterization of glutathione S-transferase isozymes from sorghum. [1998.07]
Antioxidant and detoxifying enzymes in the liver and kidney of pheasants after intoxication by herbicides MCPA and ANITEN I. [1998]
Role of glutathione S-transferases in the resistance of human colon cancer cell lines to doxorubicin. [1998.03.01]
Age dependent differential effects of cigarette smoke on hepatic and pulmonary xenobiotic metabolizing enzymes in rats. [1997]
Mechanism-based phage display selection of active-site mutants of human glutathione transferase A1-1 catalyzing SNAr reactions. [1997.09.16]
Combined effects of ethanol and cigarette smoke on hepatic and pulmonary xenobiotic metabolizing enzymes in rats. [1996.12.20]
Lentinan enhances sensitivity of mouse colon 26 tumor to cis-diamminedichloroplatinum (II) and decreases glutathione transferase expression. [1996.11]
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