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Edecrin (Ethacrynic Acid) - Summary

 

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EDECRIN SUMMARY


EDECRIN®
TABLETS
(ETHACRYNIC ACID)
and
EDECRIN® SODIUM
INTRAVENOUS
(ETHACRYNATE SODIUM)

Ethacrynic acid is an unsaturated ketone derivative of an aryloxyacetic acid.

EDECRIN is indicated for treatment of edema when an agent with greater diuretic potential than those commonly employed is required.

  1. Treatment of the edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome.
  2. Short-term management of ascites due to malignancy, idiopathic edema, and lymphedema.
  3. Short-term management of hospitalized pediatric patients, other than infants, with congenital heart disease or the nephrotic syndrome.
  4. Intravenous SODIUM EDECRIN is indicated when a rapid onset of diuresis is desired, e.g., in acute pulmonary edema, or when gastrointestinal absorption is impaired or oral medication is not practicable.

EDECRIN NEWS HIGHLIGHTS

Published Studies Related to Edecrin (Ethacrynic Acid)

A comparison of the effects of inhaled furosemide and ethacrynic acid on sodium-metabisulfite-induced bronchoconstriction in subjects with asthma. [1995.02]

Pharmakokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer. [1994.09]

Alternating sequential dosing with furosemide and ethacrynic acid in drug tolerance in the newborn. [1989.07]

Effects of the new ethacrynic acid oxime derivative SA12590 on intraocular pressure in cats and monkeys. [2007.08]

Cell death after co-administration of cisplatin and ethacrynic acid. [2007.04]

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Page last updated: 2007-10-18

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