ECOTRIN SUMMARY
Ecotrin enteric coated aspirin (acetylsalicylic acid) tablets available in 81mg, 325mg and 500 mg tablets for oral administration.
Vascular Indications (Ischemic Stroke, TIA, Acute MI, Prevention of Recurrent MI, Unstable Angina Pectoris, and Chronic Stable Angina Pectoris): Aspirin is indicated to: (1) Reduce the combined risk of death and nonfatal stroke in patients who have had ischemic stroke or transient ischemia of the brain due to fibrin platelet emboli, (2) reduce the risk of vascular mortality in patients with a suspected acute MI, (3) reduce the combined risk of death and nonfatal MI in patients with a previous MI or unstable angina pectoris, and (4) reduce the combined risk of MI and sudden death in patients with chronic stable angina pectoris.
Revascularization Procedures (Coronary Artery Bypass Graft (CABG), Percutaneous Transluminal Coronary Angioplasty (PTCA), and Carotid Endarterectomy): Aspirin is indicated in patients who have undergone revascularization procedures (i.e., CABG, PTCA, or carotid endarterectomy) when there is a preexisting condition for which aspirin is already indicated.
Rheumatologic Disease Indications (Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, Spondyloarthropathies, Osteoarthritis, and the Arthritis and Pleurisy of Systemic Lupus Erythematosus (SLE)): Aspirin is indicated for the relief of the signs and symptoms of rheumatoid arthritis, juvenile rheumatoid arthritis, osteoarthritis, spondyloarthropathies, and arthritis and pleurisy associated with SLE.
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ECOTRIN NEWS HIGHLIGHTS
Media Articles Related to Ecotrin (Aspirin)
PPI Cost-Effective as Co-Therapy with Aspirin for Cardiovascular Prophylaxsis
Source: MedPage Today Gastroenterology [2008.08.11]
Anti-Clotting Drug as Good as Aspirin at Stopping Second Stroke
Source: MedicineNet cilostazol Specialty [2008.05.06]
Aspirin May Lower Breast Cancer Risk
Source: MedicineNet celecoxib Specialty [2008.03.11]
Aspirin may not provide optimum anti-coagulation for all patients
Source: The Doctors Lounge - Hematology
Aspirin as effective as warfarin and safer in stroke prevention
Source: The Doctors Lounge - Neurology
Published Studies Related to Ecotrin (Aspirin)
An assessment of the joint associations of aspirin and statin use with C-reactive protein concentration. [2008.07]
Aspirin, clopidogrel, and warfarin: is the combination appropriate and effective or inappropriate and too dangerous? [2008.06]
Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS): A randomized, double-blind, aspirin-controlled trial. [2008.06]
Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects. [2008.06]
Cilostazol as an alternative to aspirin after ischaemic stroke: a randomised, double-blind, pilot study. [2008.06]
Clinical Trials Related to Ecotrin (Aspirin)
Evaluate Relative Bioavailability of PA32540 (Asa/Omeprazole), Its Aspirin Component, and EcotrinŽ in Healthy Volunteers [Completed]
Modified-Release Dipyridamole/Aspirin (200mg/25mg bd) Versus Aspirin (75mg) in Aspirin-Resistant Patients [Completed]
Low Molecular Weight Heparin and Aspirin in the Treatment of Recurrent Pregnancy Loss: A RCT [Terminated]
Danish Aspirin Resistance Trial - Pilot Study [Completed]
Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial [Active, not recruiting]
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