1% Econopred® Plus
ECONOPRED® and ECONOPRED® Plus (Prednisolone Acetate) are adrenocortical steroid products prepared as sterile ophthalmic suspensions.
Econopred (prednisolone OPHTHALMIC) is indicated for the following:
Steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitides, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation; corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies.
Published Studies Related to Econopred (Prednisolone Ophthalmic)
A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery. [2011.10]
PURPOSE: To compare the effects of 2 corticosteroids on corneal thickness and visual acuity after cataract surgery. DESIGN: Multicenter, randomized, contralateral-eye, double-masked trial... CONCLUSIONS: In this high-dose pulsed-therapy regimen, difluprednate reduced inflammation more effectively than prednisolone acetate, resulting in more rapid return of vision. Difluprednate was superior at protecting the cornea and reducing macular thickening after cataract surgery. Copyright (c) 2011 Elsevier Inc. All rights reserved.
Randomized trial of intravitreal clindamycin and dexamethasone versus pyrimethamine, sulfadiazine, and prednisolone in treatment of ocular toxoplasmosis. [2011.01]
PURPOSE: To compare the efficacy of intravitreal injection of clindamycin and dexamethasone with classic treatment for ocular toxoplasmosis... CONCLUSIONS: Intravitreal injection of clindamycin and dexamethasone may be an acceptable alternative to the classic treatment in ocular toxoplasmosis. It may offer the patient more convenience, a safer systemic side effect profile, greater availability, and fewer follow-up visits and hematologic evaluations. Copyright (c) 2011 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.
Methylprednisolone applied directly to the round window reduces dizziness after cochlear implantation: a randomized clinical trial. 
This prospective, double-blind controlled, randomized clinical trial of 43 adults showed that topical methylprednisolone applied to the round window during cochlear implantation was effective in protecting inner ear function. Postoperative vestibular disturbance was significantly lower in the steroid group (5%) than the control group (29%)...
Comparison of orbital floor triamcinolone acetonide and oral prednisolone for cataract surgery management in patients with non-infectious uveitis. [2010.05]
PURPOSE: To compare orbital floor triamcinolone acetonide and oral prednisolone in cataract surgery in patients with chronic non-infectious uveitis with regard to visual outcome, postoperative inflammation and macular edema... CONCLUSIONS: A single intraoperative orbital floor injection of triamcinolone acetonide is as effective on postoperative inflammation, macular edema, and visual outcome as a 4-week course of postoperative oral prednisolone in cataract surgery with IOL implantation in uveitis patients.
Effect of oral prednisolone on visual outcomes and complications after scleral buckling. [2010.03]
PURPOSE: To evaluate the effect of oral prednisolone on visual outcomes and complications of scleral buckling (SB) in phakic eyes with acute rhegmatogenous retinal detachment (RRD)... CONCLUSIONS: Postoperative oral prednisolone does not seem to improve the visual outcomes and complications of scleral buckling in simple phakic RRD.
Clinical Trials Related to Econopred (Prednisolone Ophthalmic)
A Comparison of Three Different Formulations of Prednisolone Acetate 1% [Completed]
Prednisolone Priming Study in Patients With Chronic Hepatitis B [Recruiting]
To investigate whether ALT rebound following corticosteroid priming enhances response to
The primary endpoint will be the 1-year HBe-Ag seroconversion rate with or without
A summary table will be presented as frequency tables for categorical variables as number,
and percentage, whereas descriptive tables for continuous variables as number, mean ± SD and
median (minimum, maximum). All statistical assessments will be two-sided and evaluated at
significance level of 0. 05. Continuous variables will be analyzed using t-test, or ANOVA,
and categorical variables will be analyzed using chi-square or Fisher's exact test. A
non-parametric method, Wilcoxon rank-sum or sign-rank tests will be conducted for
continuous, and categorical variables if data is far from normal distribution.
Biomarkers of Prednisolone Treatment (P05888) [Completed]
- To identify a biomarker or biomarker-set for the adverse metabolic effects of various
doses of prednisolone treatment.
- To describe the PK of prednisolone and PD of a series of biomarkers.
- To identify biomarkers that reflect side effects of prednisolone.
- To elucidate part of the mechanisms by which prednisolone induces metabolic changes.
Preoperative Methylprednisolone in Endovascular Aortic Repair [Completed]
The Efficacy of Three Months-prednisolone Therapy for Chronic Eosinophilic Pneumonia [Completed]
A comparison of 3 months-prednisolone administration with 6 months-prednisolone therapy in
the treatment of chronic eosinophilic pneumonia. Three months-prednisolone administration
may be as effective as 6 months-therapy.