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Dyazide (Hydrochlorothiazide / Triamterene) - Side Effects and Adverse Reactions

 



ADVERSE REACTIONS

Adverse effects are listed in decreasing order of severity.

Hypersensitivity

Anaphylaxis, rash, urticaria, subacute cutaneous lupus erythematosus-like reactions, photosensitivity.

Cardiovascular

Arrhythmia, postural hypotension.

Metabolic

Diabetes mellitus, hyperkalemia, hypokalemia, hyponatremia, acidosis, hypercalcemia, hyperglycemia, glycosuria, hyperuricemia, hypochloremia.

Gastrointestinal

Jaundice and/or liver enzyme abnormalities, pancreatitis, nausea and vomiting, diarrhea, constipation, abdominal pain.

Renal

Acute renal failure (one case of irreversible renal failure has been reported), interstitial nephritis, renal stones composed primarily of triamterene, elevated BUN, and serum creatinine, abnormal urinary sediment.

Hematologic

Leukopenia, thrombocytopenia and purpura, megaloblastic anemia.

Musculoskeletal

Muscle cramps.

Central Nervous System

Weakness, fatigue, dizziness, headache, dry mouth.

Miscellaneous

Impotence, sialadenitis.

Thiazides alone have been shown to cause the following additional adverse reactions:

Central Nervous System

Paresthesias, vertigo.

Ophthalmic

Xanthopsia, transient blurred vision.

Respiratory

Allergic pneumonitis, pulmonary edema, respiratory distress.

Other

Necrotizing vasculitis, exacerbation of lupus.

Hematologic

Aplastic anemia, agranulocytosis, hemolytic anemia.

Neonate and infancy

Thrombocytopenia and pancreatitis−rarely, in newborns whose mothers have received thiazides during pregnancy.



REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO DYAZIDE

Below is a sample of reports where side effects / adverse reactions may be related to Dyazide. The information is not vetted and should not be cosidered as verified clinical evidence.

Possible Dyazide side effects / adverse reactions in 75 year old male

Reported by a consumer/non-health professional from United States on 2007-01-17

Patient: 75 year old male

Reactions: Urinary Incontinence

Suspect drug(s):
Dyazide

Other drugs received by patient: Lipitor; Toprol-XL



Possible Dyazide side effects / adverse reactions in 87 year old female

Reported by a consumer/non-health professional from United States on 2007-04-25

Patient: 87 year old female

Reactions: Nephrolithiasis, Kidney Infection

Suspect drug(s):
Daraprim
    Indication: Drug USE FOR Unknown Indication

Dyazide
    End date: 1988-01-01



Possible Dyazide side effects / adverse reactions in 86 year old female

Reported by a pharmacist from United States on 2007-05-29

Patient: 86 year old female

Reactions: Confusional State, Mental Status Changes

Adverse event resulted in: hospitalization

Suspect drug(s):
Dyazide

Other drugs received by patient: Synthroid; Boniva; Cartia XT; Lorazepam; CA; Pred



See index of all Dyazide side effect reports >>

Drug label data at the top of this Page last updated: 2007-08-14

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