CONTRAINDICATIONS
Antikaliuretic Therapy and Potassium Supplementation
DYAZIDE should not be given to patients receiving other potassium-sparing agents such as spironolactone, amiloride, or other formulations containing triamterene. Concomitant potassium-containing salt substitutes should also not be used.
Potassium supplementation should not be used with DYAZIDE except in severe cases of hypokalemia. Such concomitant therapy can be associated with rapid increases in serum potassium levels. If potassium supplementation is used, careful monitoring of the serum potassium level is necessary.
Impaired Renal Function
DYAZIDE is contraindicated in patients with anuria, acute and chronic renal insufficiency or significant renal impairment.
Hypersensitivity
Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication.
Hyperkalemia
DYAZIDE should not be used in patients with preexisting elevated serum potassium.
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