ADVERSE REACTIONS
Gastrointestinal
Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS). Dyspepsia, nausea and vomiting have been reported rarely. Diarrhea has also occurred.
Hypersensitivity
Allergies (in the form of rash, urticaria, angioedema, and pruritus) have been observed. These reactions usually subsided upon discontinuation of the drug. Anaphylaxis has also been reported.
Other
Other reactions have included hepatic dysfunction including cholestasis and elevations in serum transaminase, genital pruritus, genital moniliasis, vaginitis, moderate transient neutropenia, fever. Agranulocytosis, thrombocytopenia, idiosyncratic hepatic failure, erythema multiforme, Stevens-Johnson syndrome, serum sickness, and arthralgia have been rarely reported.
In addition to the adverse reactions listed above which have been observed in patients treated with cefadroxil, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics:
Toxic epidermal necrolysis, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, aplastic anemia, hemolytic anemia, hemorrhage, prolonged prothrombin time, positive Coombs’ test, increased BUN, increased creatinine, elevated alkaline phosphatase, elevated aspartate aminotransferase (AST), elevated alanine aminotransferase (ALT), elevated bilirubin, elevated LDH, eosinophilia, pancytopenia, neutropenia.
Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment, when the dosage was not reduced (see DOSAGE AND ADMINISTRATION and OVERDOSAGE). If seizures associated with drug therapy occur, the drug should be discontinued. Anticonvulsant therapy can be given if clinically indicated.
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REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO DURICEF
Below is a sample of reports where side effects / adverse reactions may be related to Duricef. The information is not vetted and should not be cosidered as verified clinical evidence.
Possible Duricef side effects / adverse reactions in 31 year old female
Reported by a individual with unspecified qualification from Sweden on 2007-01-29
Patient: 31 year old female
Reactions: Flushing, Thrombosis, Toxic Epidermal Necrolysis, Eye Excision, Unevaluable Event, Eye Infection
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Duricef
Dosage: oral
Administration route: Oral
Indication: Nasopharyngeal Disorder
Start date: 2006-08-24
End date: 2006-08-26
Duricef
Dosage: oral
Administration route: Oral
Indication: Pharyngeal Oedema
Start date: 2006-08-24
End date: 2006-08-26
Duricef
Dosage: oral
Administration route: Oral
Indication: Pharyngolaryngeal Pain
Start date: 2006-08-24
End date: 2006-08-26
Ibuprofen
Dosage: oral
Administration route: Oral
Indication: Nasopharyngeal Disorder
Start date: 2006-08-24
End date: 2006-08-26
Ibuprofen
Dosage: oral
Administration route: Oral
Indication: Pharyngeal Oedema
Start date: 2006-08-24
End date: 2006-08-26
Ibuprofen
Dosage: oral
Administration route: Oral
Indication: Pharyngolaryngeal Pain
Start date: 2006-08-24
End date: 2006-08-26
Possible Duricef side effects / adverse reactions in 59 year old female
Reported by a individual with unspecified qualification from Estonia on 2007-02-22
Patient: 59 year old female
Reactions: Angioedema, Dyspnoea, Tongue Oedema, Pyrexia, Local Swelling, Face Oedema, Oedema Mouth, Urinary Retention, Feeling Abnormal
Suspect drug(s):
Duricef
Possible Duricef side effects / adverse reactions in 40 year old female
Reported by a physician from France on 2007-03-13
Patient: 40 year old female
Reactions: Pruritus Generalised, Type IV Hypersensitivity Reaction, Purpura, Epistaxis
Suspect drug(s):
Duricef
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