Duo-Medihaler (Isoproterenol Hydrochloride / Phenylephrine Bitartrate Inhalation) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The following adverse effects, listed by organ system in decreasing frequency have been associated with the use of DUO-MEDIHALER and are similar to those produced by other sympathomimetic agents:

	Isoproterenol	Phenylephrine
Cardio-	palpitation	bradycardia
vascular:	tachycardia	decreased cardiac
	coronary	output
	insufficiency	blanching of skin
	flushing of skin	peripheral and
	blood pressure	visceral vaso-
	changes	constriction
	cardiac arrhythmias	cardiac
	cardiac arrest	irregularities
	anginal pain	anginal pain
	Isoproterenol	Phenylephrine
Pulmonary:	paradoxical airway	respiratory
	resistance	distress
	rebound broncho-
	spasm
Central Nerv-	headache	tremor
ous System:	tremor	dizziness
	vertigo	central excitation
	central excitation	pilomotor
	insomnia	response
Gastro-	nausea
Intestinal: