WARNING
It is recommended that DTIC-Dome (dacarbazine) be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.
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Hemopoietic depression is the most common toxicity with DTIC-Dome (See Warnings).
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Hepatic necrosis has been reported (See Warnings).
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Studies have demonstrated this agent to have a carcinogenic and teratogenic effect when used in animals.
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In treatment of each patient, the physician must weigh carefully the possibility of achieving therapeutic benefit against the risk of toxicity.
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